Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators
Nguyen, Hung N., Noss, Erika H., Mizoguchi, Fumitaka, Huppertz, Christine, Wei, Kevin S., Watts, Gerald F.M., Brenner, Michael B.
Published in Immunity (Cambridge, Mass.) (21.02.2017)
Published in Immunity (Cambridge, Mass.) (21.02.2017)
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Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production
Boilard, Eric, Nigrovic, Peter A, Larabee, Katherine, Watts, Gerald F.M, Coblyn, Jonathan S, Weinblatt, Michael E, Massarotti, Elena M, Remold-O'Donnell, Eileen, Farndale, Richard W, Ware, Jerry, Lee, David M
Published in Science (American Association for the Advancement of Science) (29.01.2010)
Published in Science (American Association for the Advancement of Science) (29.01.2010)
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Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
King, Irah L, Fortier, Anne, Tighe, Michael, Dibble, John, Watts, Gerald F M, Veerapen, Natacha, Haberman, Ann M, Besra, Gurdyal S, Mohrs, Markus, Brenner, Michael B, Leadbetter, Elizabeth A
Published in Nature immunology (01.01.2012)
Published in Nature immunology (01.01.2012)
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Cadherin-11 in Synovial Lining Formation and Pathology in Arthritis
Lee, David M, Kiener, Hans P, Agarwal, Sandeep K, Noss, Erika H, Watts, Gerald F.M, Chisaka, Osamu, Takeichi, Masatoshi, Brenner, Michael B
Published in Science (American Association for the Advancement of Science) (16.02.2007)
Published in Science (American Association for the Advancement of Science) (16.02.2007)
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Innate Recognition of Cell Wall β-Glucans Drives Invariant Natural Killer T Cell Responses against Fungi
Cohen, Nadia R., Tatituri, Raju V.V., Rivera, Amariliz, Watts, Gerald F.M., Kim, Edy Y., Chiba, Asako, Fuchs, Beth B., Mylonakis, Eleftherios, Besra, Gurdyal S., Levitz, Stuart M., Brigl, Manfred, Brenner, Michael B.
Published in Cell host & microbe (17.11.2011)
Published in Cell host & microbe (17.11.2011)
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Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d
Muindi, Karen, Cernadas, Manuela, Watts, Gerald F.M, Royle, Louise, Neville, David C.A, Dwek, Raymond A, Besra, Gurdyal S, Rudd, Pauline M, Butters, Terry D, Brenner, Michael B
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.02.2010)
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Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes
Valencia, Xavier, Higgins, Jonathan M G, Kiener, Hans P, Lee, David M, Podrebarac, Theresa A, Dascher, Christopher C, Watts, Gerald F M, Mizoguchi, Emiko, Simmons, Barry, Patel, Dhavalkumar D, Bhan, Atul K, Brenner, Michael B
Published in The Journal of experimental medicine (20.12.2004)
Published in The Journal of experimental medicine (20.12.2004)
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Notch signalling drives synovial fibroblast identity and arthritis pathology
Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L, Gao, Anqi, Watts, Gerald F M, Major, Triin, Croft, Adam P, Watts, Jordan, Blazar, Philip E, Lange, Jeffrey K, Thornhill, Thomas S, Filer, Andrew, Raza, Karim, Donlin, Laura T, Siebel, Christian W, Buckley, Christopher D, Raychaudhuri, Soumya, Brenner, Michael B
Published in Nature (London) (01.06.2020)
Published in Nature (London) (01.06.2020)
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IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies
Friedrich, Matthias, Pohin, Mathilde, Jackson, Matthew A, Korsunsky, Ilya, Bullers, Samuel J, Rue-Albrecht, Kevin, Christoforidou, Zoe, Sathananthan, Dharshan, Thomas, Tom, Ravindran, Rahul, Tandon, Ruchi, Peres, Raphael Sanches, Sharpe, Hannah, Wei, Kevin, Watts, Gerald F M, Mann, Elizabeth H, Geremia, Alessandra, Attar, Moustafa, McCuaig, Sarah, Thomas, Lloyd, Collantes, Elena, Uhlig, Holm H, Sansom, Stephen N, Easton, Alistair, Raychaudhuri, Soumya, Travis, Simon P, Powrie, Fiona M
Published in Nature medicine (01.11.2021)
Published in Nature medicine (01.11.2021)
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Granzyme K + CD8 T cells form a core population in inflamed human tissue
Jonsson, A Helena, Zhang, Fan, Dunlap, Garrett, Gomez-Rivas, Emma, Watts, Gerald F M, Faust, Heather J, Rupani, Karishma Vijay, Mears, Joseph R, Meednu, Nida, Wang, Runci, Keras, Gregory, Coblyn, Jonathan S, Massarotti, Elena M, Todd, Derrick J, Anolik, Jennifer H, McDavid, Andrew, Wei, Kevin, Rao, Deepak A, Raychaudhuri, Soumya, Brenner, Michael B
Published in Science translational medicine (15.06.2022)
Published in Science translational medicine (15.06.2022)
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CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts
Slowikowski, Kamil, Nguyen, Hung N., Noss, Erika H., Simmons, Daimon P., Mizoguchi, Fumitaka, Watts, Gerald F. M., Gurish, Michael F., Brenner, Michael B., Raychaudhuri, Soumya
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2020)
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Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions
Gutierrez-Arcelus, Maria, Teslovich, Nikola, Mola, Alex R, Polidoro, Rafael B, Nathan, Aparna, Kim, Hyun, Hannes, Susan, Slowikowski, Kamil, Watts, Gerald F M, Korsunsky, Ilya, Brenner, Michael B, Raychaudhuri, Soumya, Brennan, Patrick J
Published in Nature communications (08.02.2019)
Published in Nature communications (08.02.2019)
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Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
Brigl, Manfred, Tatituri, Raju V V, Watts, Gerald F M, Bhowruth, Veemal, Leadbetter, Elizabeth A, Barton, Nathaniel, Cohen, Nadia R, Hsu, Fong-Fu, Besra, Gurdyal S, Brenner, Michael B
Published in The Journal of experimental medicine (06.06.2011)
Published in The Journal of experimental medicine (06.06.2011)
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Structural determination of lipid antigens captured at the CD1d–T-cell receptor interface
Brennan, Patrick J., Cheng, Tan-Yun, Pellicci, Daniel G., Watts, Gerald F.M., Veerapen, Natacha, Young, David C., Rossjohn, Jamie, Besra, Gurdyal S., Godfrey, Dale I., Brenner, Michael B., Moody, D. Branch
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.2017)
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Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
Korsunsky, Ilya, Wei, Kevin, Pohin, Mathilde, Kim, Edy Y, Barone, Francesca, Major, Triin, Taylor, Emily, Ravindran, Rahul, Kemble, Samuel, Watts, Gerald F M, Jonsson, A Helena, Jeong, Yunju, Athar, Humra, Windell, Dylan, Kang, Joyce B, Friedrich, Matthias, Turner, Jason, Nayar, Saba, Fisher, Benjamin A, Raza, Karim, Marshall, Jennifer L, Croft, Adam P, Tamura, Tomoyoshi, Sholl, Lynette M, Vivero, Marina, Rosas, Ivan O, Bowman, Simon J, Coles, Mark, Frei, Andreas P, Lassen, Kara, Filer, Andrew, Powrie, Fiona, Buckley, Christopher D, Brenner, Michael B, Raychaudhuri, Soumya
Published in Med (New York, N.Y. : Online) (08.07.2022)
Published in Med (New York, N.Y. : Online) (08.07.2022)
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Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation
Madarampalli, Bhanupriya, Watts, Gerald F.M., Panipinto, Paul M., Nguygen, Hung N., Brenner, Michael B., Noss, Erika H.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2019)
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Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction
Brennan, Patrick J., Tatituri, Raju V. V., Heiss, Christian, Watts, Gerald F. M., Hsu, Fong-Fu, Veerapen, Natacha, Cox, Liam R., Azadi, Parastoo, Besra, Gurdyal S., Brenner, Michael B.
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
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Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs
Tatituri, Raju V. V., Watts, Gerald F. M., Bhowruth, Veemal, Barton, Nathaniel, Rothchild, Alissa, Hsu, Fong-Fu, Almeida, Catarina F., Cox, Liam R., Eggeling, Lothar, Cardell, Susanna, Rossjohn, Jamie, Godfrey, Dale I., Behar, Samuel M., Besra, Gurdyal S., Brenner, Michael B., Brigl, Manfred
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
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