Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap
Dunphy, Rhys W, Wahid, Ayla A, Back, Catherine R, Martin, Rebecca L, Watts, Andrew G, Dodson, Charlotte A, Crennell, Susan J, van den Elsen, Jean M H
Published in Frontiers in immunology (25.05.2022)
Published in Frontiers in immunology (25.05.2022)
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The Structure of Clostridium perfringens NanI Sialidase and Its Catalytic Intermediates
Newstead, Simon L., Potter, Jane A., Wilson, Jennifer C., Xu, Guogang, Chien, Chin-Hsiang, Watts, Andrew G., Withers, Stephen G., Taylor, Garry L.
Published in The Journal of biological chemistry (04.04.2008)
Published in The Journal of biological chemistry (04.04.2008)
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Insights Into the Structure-Function Relationships of Dimeric C3d Fragments
Wahid, Ayla A, Dunphy, Rhys W, Macpherson, Alex, Gibson, Beth G, Kulik, Liudmila, Whale, Kevin, Back, Catherine, Hallam, Thomas M, Alkhawaja, Bayan, Martin, Rebecca L, Meschede, Ingrid, Laabei, Maisem, Lawson, Alastair D G, Holers, V Michael, Watts, Andrew G, Crennell, Susan J, Harris, Claire L, Marchbank, Kevin J, van den Elsen, Jean M H
Published in Frontiers in immunology (09.08.2021)
Published in Frontiers in immunology (09.08.2021)
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Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant
Yang, Yi, Back, Catherine R, Gräwert, Melissa A, Wahid, Ayla A, Denton, Harriet, Kildani, Rebecca, Paulin, Joshua, Wörner, Kristin, Kaiser, Wolgang, Svergun, Dmitri I, Sartbaeva, Asel, Watts, Andrew G, Marchbank, Kevin J, van den Elsen, Jean M H
Published in Frontiers in immunology (11.01.2019)
Published in Frontiers in immunology (11.01.2019)
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Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis
Withers, Stephen G, Lairson, Luke L, Watts, Andrew G, Wakarchuk, Warren W
Published in Nature chemical biology (01.12.2006)
Published in Nature chemical biology (01.12.2006)
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Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile
WATTS, Andrew G., DAMAGER, Iben, AMAYA, Maria L., BUSCHIAZZO, Alejandro, ALZARI, Pedro, FRASCH, Alberto C., WITHERS, Stephen G.
Published in Journal of the American Chemical Society (25.06.2003)
Published in Journal of the American Chemical Society (25.06.2003)
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Conservation of Structure and Mechanism in Primary and Secondary Transporters Exemplified by SiaP, a Sialic Acid Binding Virulence Factor from Haemophilus influenzae
Müller, Axel, Severi, Emmanuele, Mulligan, Christopher, Watts, Andrew G., Kelly, David J., Wilson, Keith S., Wilkinson, Anthony J., Thomas, Gavin H.
Published in The Journal of biological chemistry (04.08.2006)
Published in The Journal of biological chemistry (04.08.2006)
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High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment
Sánchez-Magraner, Lissete, Miles, James, Baker, Claire L, Applebee, Christopher J, Lee, Dae-Jin, Elsheikh, Somaia, Lashin, Shaimaa, Withers, Katriona, Watts, Andrew G, Parry, Richard, Edmead, Christine, Lopez, Jose Ignacio, Mehta, Raj, Italiano, Antoine, Ward, Stephen G, Parker, Peter J, Larijani, Banafshé
Published in Cancer research (Chicago, Ill.) (01.10.2020)
Published in Cancer research (Chicago, Ill.) (01.10.2020)
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Dissecting the stability of Atezolizumab with renewable amino acid-based ionic liquids: Colloidal stability and anticancer activity under thermal stress
Alkhawaja, Bayan, Al-Akayleh, Faisal, Al-Rubaye, Zaid, AlDabet, Ghayda', Bustami, Muna, Smairat, Maisa'a, Agha, Ahmed S.A.A., Nasereddin, Jehad, Qinna, Nidal, Michael, Andreas, Watts, Andrew G.
Published in International journal of biological macromolecules (01.06.2024)
Published in International journal of biological macromolecules (01.06.2024)
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Mechanism-Based Covalent Neuraminidase Inhibitors with Broad-Spectrum Influenza Antiviral Activity
Kim, Jin-Hyo, Resende, Ricardo, Wennekes, Tom, Chen, Hong-Ming, Bance, Nicole, Buchini, Sabrina, Watts, Andrew G., Pilling, Pat, Streltsov, Victor A., Petric, Martin, Liggins, Richard, Barrett, Susan, McKimm-Breschkin, Jennifer L., Niikura, Masahiro, Withers, Stephen G.
Published in Science (American Association for the Advancement of Science) (05.04.2013)
Published in Science (American Association for the Advancement of Science) (05.04.2013)
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Tripartite ATP-independent Periplasmic (TRAP) Transporters Use an Arginine-mediated Selectivity Filter for High Affinity Substrate Binding
Fischer, Marcus, Hopkins, Adam P., Severi, Emmanuele, Hawkhead, Judith, Bawdon, Daniel, Watts, Andrew G., Hubbard, Roderick E., Thomas, Gavin H.
Published in The Journal of biological chemistry (06.11.2015)
Published in The Journal of biological chemistry (06.11.2015)
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Structural and Functional Analysis of Anti-Influenza Activity of 4‑, 7‑, 8- and 9‑Deoxygenated 2,3-Difluoro‑N‑acetylneuraminic Acid Derivatives
McKimm-Breschkin, Jennifer L, Barrett, Susan, Pilling, Patricia A, Hader, Stefan, Watts, Andrew G, Streltsov, Victor A
Published in Journal of medicinal chemistry (08.03.2018)
Published in Journal of medicinal chemistry (08.03.2018)
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The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase
Chen, Zexin, Marcé, Patricia, Resende, Ricardo, Alzari, Pedro M., Frasch, A. Carlos, van den Elsen, Jean M.H., Crennell, Susan J., Watts, Andrew G.
Published in European journal of medicinal chemistry (05.10.2018)
Published in European journal of medicinal chemistry (05.10.2018)
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Evaluation of the physicochemical and functional stability of diluted REMSIMA® upon extended storage—A study compliant with NHS (UK) guidance
Young, Benjamin L., Khan, Monika Ali, Chapman, Terry J., Parry, Richard, Connolly, Maria A., Watts, Andrew G.
Published in International journal of pharmaceutics (30.12.2015)
Published in International journal of pharmaceutics (30.12.2015)
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Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Amaya, Marı́a Fernanda, Watts, Andrew G, Damager, Iben, Wehenkel, Annemarie, Nguyen, Tong, Buschiazzo, Alejandro, Paris, Gastón, Frasch, A.Carlos, Withers, Stephen G, Alzari, Pedro M
Published in Structure (London) (01.05.2004)
Published in Structure (London) (01.05.2004)
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