Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
McEwan, William A, Tam, Jerry C H, Watkinson, Ruth E, Bidgood, Susanna R, Mallery, Donna L, James, Leo C
Published in Nature immunology (01.04.2013)
Published in Nature immunology (01.04.2013)
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Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21
Fletcher, Adam J., Mallery, Donna L., Watkinson, Ruth E., Dickson, Claire F., James, Leo C.
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (11.08.2015)
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TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus
Watkinson, Ruth E, McEwan, William A, Tam, Jerry C H, Vaysburd, Marina, James, Leo C
Published in PLoS pathogens (01.10.2015)
Published in PLoS pathogens (01.10.2015)
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Effects of BNT162b2 mRNA vaccine on COVID-19 infection and hospitalisation amongst older people: matched case control study for England
Mason, Thomas F. D, Whitston, Matt, Hodgson, Jack, Watkinson, Ruth E, Lau, Yiu-Shing, Abdulrazeg, Omnia, Sutton, Matt
Published in BMC medicine (18.10.2021)
Published in BMC medicine (18.10.2021)
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Dissecting ELANE neutropenia pathogenicity by human HSC gene editing
Rao, Shuquan, Yao, Yao, Soares de Brito, Josias, Yao, Qiuming, Shen, Anne H., Watkinson, Ruth E., Kennedy, Alyssa L., Coyne, Steven, Ren, Chunyan, Zeng, Jing, Serbin, Anna Victoria, Studer, Sabine, Ballotti, Kaitlyn, Harris, Chad E., Luk, Kevin, Stevens, Christian S., Armant, Myriam, Pinello, Luca, Wolfe, Scot A., Chiarle, Roberto, Shimamura, Akiko, Lee, Benhur, Newburger, Peter E., Bauer, Daniel E.
Published in Cell stem cell (06.05.2021)
Published in Cell stem cell (06.05.2021)
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Intracellular antibody receptor TRIM21 prevents fatal viral infection
Vaysburd, Marina, Watkinson, Ruth E., Cooper, Helen, Reed, Martin, O'Connell, Kevin, Smith, Jackie, Cruickshanks, James, James, Leo C.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
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Antibody-antigen kinetics constrain intracellular humoral immunity
Bottermann, Maria, Lode, Heidrun Elisabeth, Watkinson, Ruth E., Foss, Stian, Sandlie, Inger, Andersen, Jan Terje, James, Leo C.
Published in Scientific reports (24.11.2016)
Published in Scientific reports (24.11.2016)
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TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
Foss, Stian, Watkinson, Ruth E, Grevys, Algirdas, McAdam, Martin B, Bern, Malin, Høydahl, Lene Stokken, Dalhus, Bjørn, Michaelsen, Terje E, Sandlie, Inger, James, Leo C, Andersen, Jan Terje
Published in The Journal of immunology (1950) (15.04.2016)
Published in The Journal of immunology (1950) (15.04.2016)
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Intracellular Antibody Immunity
Watkinson, Ruth E., McEwan, William A., James, Leo C.
Published in Journal of clinical immunology (01.07.2014)
Published in Journal of clinical immunology (01.07.2014)
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Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity
Bottermann, Maria, Lode, Heidrun Elisabeth, Watkinson, Ruth E, Foss, Stian, Sandlie, Inger, Andersen, Jan Terje, James, Leo C
Published in Scientific reports (06.04.2017)
Published in Scientific reports (06.04.2017)
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Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase
Cox, Robert M., Sourimant, Julien, Toots, Mart, Yoon, Jeong-Joong, Ikegame, Satoshi, Govindarajan, Mugunthan, Watkinson, Ruth E., Thibault, Patricia, Makhsous, Negar, Lin, Michelle J., Marengo, Jose R., Sticher, Zachary, Kolykhalov, Alexander A., Natchus, Michael G., Greninger, Alexander L., Lee, Benhur, Plemper, Richard K.
Published in Nature microbiology (01.10.2020)
Published in Nature microbiology (01.10.2020)
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Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm
Hung, Chuan-Tien, Haas, Griffin D, Watkinson, Ruth E, Chiu, Hsin-Ping, Kowdle, Shreyas, Stevens, Christian S, Park, Arnold, Wohlschlegel, James A, Thibault, Patricia A, Lee, Benhur
Published in bioRxiv (07.09.2024)
Published in bioRxiv (07.09.2024)
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