Somatic CpG hypermutation is associated with mismatch repair deficiency in cancer
Flynn, Aidan, Waszak, Sebastian M, Weischenfeldt, Joachim
Published in Molecular systems biology (02.09.2024)
Published in Molecular systems biology (02.09.2024)
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Journal Article
Population Variation and Genetic Control of Modular Chromatin Architecture in Humans
Waszak, Sebastian M., Delaneau, Olivier, Gschwind, Andreas R., Kilpinen, Helena, Raghav, Sunil K., Witwicki, Robert M., Orioli, Andrea, Wiederkehr, Michael, Panousis, Nikolaos I., Yurovsky, Alisa, Romano-Palumbo, Luciana, Planchon, Alexandra, Bielser, Deborah, Padioleau, Ismael, Udin, Gilles, Thurnheer, Sarah, Hacker, David, Hernandez, Nouria, Reymond, Alexandre, Deplancke, Bart, Dermitzakis, Emmanouil T.
Published in Cell (27.08.2015)
Published in Cell (27.08.2015)
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Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
Weischenfeldt, Joachim, Dubash, Taronish, Drainas, Alexandros P, Mardin, Balca R, Chen, Yuanyuan, Stütz, Adrian M, Waszak, Sebastian M, Bosco, Graziella, Halvorsen, Ann Rita, Raeder, Benjamin, Efthymiopoulos, Theocharis, Erkek, Serap, Siegl, Christine, Brenner, Hermann, Brustugun, Odd Terje, Dieter, Sebastian M, Northcott, Paul A, Petersen, Iver, Pfister, Stefan M, Schneider, Martin, Solberg, Steinar K, Thunissen, Erik, Weichert, Wilko, Zichner, Thomas, Thomas, Roman, Peifer, Martin, Helland, Aslaug, Ball, Claudia R, Jechlinger, Martin, Sotillo, Rocio, Glimm, Hanno, Korbel, Jan O
Published in Nature genetics (01.01.2017)
Published in Nature genetics (01.01.2017)
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A dual program for translation regulation in cellular proliferation and differentiation
Gingold, Hila, Tehler, Disa, Christoffersen, Nanna R, Nielsen, Morten M, Asmar, Fazila, Kooistra, Susanne M, Christophersen, Nicolaj S, Christensen, Lise Lotte, Borre, Michael, Sørensen, Karina D, Andersen, Lars D, Andersen, Claus L, Hulleman, Esther, Wurdinger, Tom, Ralfkiær, Elisabeth, Helin, Kristian, Grønbæk, Kirsten, Ørntoft, Torben, Waszak, Sebastian M, Dahan, Orna, Pedersen, Jakob Skou, Lund, Anders H, Pilpel, Yitzhak
Published in Cell (11.09.2014)
Published in Cell (11.09.2014)
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Journal Article
Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription
Kilpinen, Helena, Waszak, Sebastian M., Gschwind, Andreas R., Raghav, Sunil K., Witwicki, Robert M., Orioli, Andrea, Migliavacca, Eugenia, Wiederkehr, Michaël, Gutierrez-Arcelus, Maria, Panousis, Nikolaos I., Yurovsky, Alisa, Lappalainen, Tuuli, Romano-Palumbo, Luciana, Planchon, Alexandra, Bielser, Deborah, Bryois, Julien, Padioleau, Ismael, Udin, Gilles, Thurnheer, Sarah, Hacker, David, Core, Leighton J., Lis, John T., Hernandez, Nouria, Reymond, Alexandre, Deplancke, Bart, Dermitzakis, Emmanouil T.
Published in Science (American Association for the Advancement of Science) (08.11.2013)
Published in Science (American Association for the Advancement of Science) (08.11.2013)
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Journal Article
Variation in Transcription Factor Binding among Humans
Kasowski, Maya, Grubert, Fabian, Heffelfinger, Christopher, Hariharan, Manoj, Asabere, Akwasi, Waszak, Sebastian M., Habegger, Lukas, Rozowsky, Joel, Shi, Minyi, Urban, Alexander E., Hong, Mi-Young, Karczewski, Konrad J., Huber, Wolfgang, Weissman, Sherman M., Gerstein, Mark B., Korbel, Jan O., Snyder, Michael
Published in Science (American Association for the Advancement of Science) (09.04.2010)
Published in Science (American Association for the Advancement of Science) (09.04.2010)
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Journal Article
Integrative Genomics Identifies the Corepressor SMRT as a Gatekeeper of Adipogenesis through the Transcription Factors C/EBPβ and KAISO
Raghav, Sunil K., Waszak, Sebastian M., Krier, Irina, Gubelmann, Carine, Isakova, Alina, Mikkelsen, Tarjei S., Deplancke, Bart
Published in Molecular cell (11.05.2012)
Published in Molecular cell (11.05.2012)
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Journal Article
A cell‐based model system links chromothripsis with hyperploidy
Mardin, Balca R, Drainas, Alexandros P, Waszak, Sebastian M, Weischenfeldt, Joachim, Isokane, Mayumi, Stütz, Adrian M, Raeder, Benjamin, Efthymiopoulos, Theocharis, Buccitelli, Christopher, Segura‐Wang, Maia, Northcott, Paul, Pfister, Stefan M, Lichter, Peter, Ellenberg, Jan, Korbel, Jan O
Published in Molecular systems biology (01.09.2015)
Published in Molecular systems biology (01.09.2015)
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Journal Article
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation
Llimos, Gerard, Gardeux, Vincent, Koch, Ute, Kribelbauer, Judith F., Hafner, Antonina, Alpern, Daniel, Pezoldt, Joern, Litovchenko, Maria, Russeil, Julie, Dainese, Riccardo, Moia, Riccardo, Mahmoud, Abdurraouf Mokhtar, Rossi, Davide, Gaidano, Gianluca, Plass, Christoph, Lutsik, Pavlo, Gerhauser, Clarissa, Waszak, Sebastian M., Boettiger, Alistair, Radtke, Freddy, Deplancke, Bart
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Personal receptor repertoires: olfaction as a model
Olender, Tsviya, Waszak, Sebastian M, Viavant, Maya, Khen, Miriam, Ben-Asher, Edna, Reyes, Alejandro, Nativ, Noam, Wysocki, Charles J, Ge, Dongliang, Lancet, Doron
Published in BMC genomics (21.08.2012)
Published in BMC genomics (21.08.2012)
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Journal Article
Genomic variation and its impact on gene expression in Drosophila melanogaster
Massouras, Andreas, Waszak, Sebastian M, Albarca-Aguilera, Monica, Hens, Korneel, Holcombe, Wiebke, Ayroles, Julien F, Dermitzakis, Emmanouil T, Stone, Eric A, Jensen, Jeffrey D, Mackay, Trudy F C, Deplancke, Bart
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Journal Article
Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
Drainas, Alexandros P., Lambuta, Ruxandra A., Ivanova, Irina, Serçin, Özdemirhan, Sarropoulos, Ioannis, Smith, Mike L., Efthymiopoulos, Theocharis, Raeder, Benjamin, Stütz, Adrian M., Waszak, Sebastian M., Mardin, Balca R., Korbel, Jan O.
Published in Cell reports (Cambridge) (07.04.2020)
Published in Cell reports (Cambridge) (07.04.2020)
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Journal Article
Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network
Gubelmann, Carine, Schwalie, Petra C, Raghav, Sunil K, Röder, Eva, Delessa, Tenagne, Kiehlmann, Elke, Waszak, Sebastian M, Corsinotti, Andrea, Udin, Gilles, Holcombe, Wiebke, Rudofsky, Gottfried, Trono, Didier, Wolfrum, Christian, Deplancke, Bart
Published in eLife (27.08.2014)
Published in eLife (27.08.2014)
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PDX models recapitulate the genetic and epigenetic landscape of pediatric T‐cell leukemia
Richter‐Pechańska, Paulina, Kunz, Joachim B, Bornhauser, Beat, von Knebel Doeberitz, Caroline, Rausch, Tobias, Erarslan‐Uysal, Büşra, Assenov, Yassen, Frismantas, Viktoras, Marovca, Blerim, Waszak, Sebastian M, Zimmermann, Martin, Seemann, Julia, Happich, Margit, Stanulla, Martin, Schrappe, Martin, Cario, Gunnar, Escherich, Gabriele, Bakharevich, Kseniya, Kirschner‐Schwabe, Renate, Eckert, Cornelia, Muckenthaler, Martina U, Korbel, Jan O, Bourquin, Jean‐Pierre, Kulozik, Andreas E
Published in EMBO molecular medicine (01.12.2018)
Published in EMBO molecular medicine (01.12.2018)
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Journal Article
Pan-cancer atlas of somatic core and linker histone mutations
Bonner, Erin R., Dawood, Adam, Gordish-Dressman, Heather, Eze, Augustine, Bhattacharya, Surajit, Yadavilli, Sridevi, Mueller, Sabine, Waszak, Sebastian M., Nazarian, Javad
Published in Npj genomic medicine (28.08.2023)
Published in Npj genomic medicine (28.08.2023)
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Journal Article
Chromatin accessibility landscape of pediatric T‐lymphoblastic leukemia and human T‐cell precursors
Erarslan‐Uysal, Büşra, Kunz, Joachim B, Rausch, Tobias, Richter‐Pechańska, Paulina, van Belzen, Ianthe AEM, Frismantas, Viktoras, Bornhauser, Beat, Ordoñez‐Rueada, Diana, Paulsen, Malte, Benes, Vladimir, Stanulla, Martin, Schrappe, Martin, Cario, Gunnar, Escherich, Gabriele, Bakharevich, Kseniya, Kirschner‐Schwabe, Renate, Eckert, Cornelia, Loukanov, Tsvetomir, Gorenflo, Matthias, Waszak, Sebastian M, Bourquin, Jean‐Pierre, Muckenthaler, Martina U, Korbel, Jan O, Kulozik, Andreas E
Published in EMBO molecular medicine (07.09.2020)
Published in EMBO molecular medicine (07.09.2020)
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Journal Article
A yeast one‐hybrid and microfluidics‐based pipeline to map mammalian gene regulatory networks
Gubelmann, Carine, Waszak, Sebastian M, Isakova, Alina, Holcombe, Wiebke, Hens, Korneel, Iagovitina, Antonina, Feuz, Jean‐Daniel, Raghav, Sunil K, Simicevic, Jovan, Deplancke, Bart
Published in Molecular systems biology (06.08.2013)
Published in Molecular systems biology (06.08.2013)
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Journal Article
Systematic inference of copy-number genotypes from personal genome sequencing data reveals extensive olfactory receptor gene content diversity
Waszak, Sebastian M, Hasin, Yehudit, Zichner, Thomas, Olender, Tsviya, Keydar, Ifat, Khen, Miriam, Stütz, Adrian M, Schlattl, Andreas, Lancet, Doron, Korbel, Jan O
Published in PLoS computational biology (01.11.2010)
Published in PLoS computational biology (01.11.2010)
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Journal Article
Versatile workflow for cell type-resolved transcriptional and epigenetic profiles from cryopreserved human lung
Llamazares-Prada, Maria, Espinet, Elisa, Mijošek, Vedrana, Schwartz, Uwe, Lutsik, Pavlo, Tamas, Raluca, Richter, Mandy, Behrendt, Annika, Pohl, Stephanie T, Benz, Naja P, Muley, Thomas, Warth, Arne, Heußel, Claus Peter, Winter, Hauke, Landry, Jonathan J M, Herth, Felix Jf, Mertens, Tinne Cj, Karmouty-Quintana, Harry, Koch, Ina, Benes, Vladimir, Korbel, Jan O, Waszak, Sebastian M, Trumpp, Andreas, Wyatt, David M, Stahl, Heiko F, Plass, Christoph, Jurkowska, Renata Z
Published in JCI insight (22.03.2021)
Published in JCI insight (22.03.2021)
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