Model‐informed drug development of voxelotor in sickle cell disease: Exposure‐response analysis to support dosing and confirm mechanism of action
Green, Michelle L., Savic, Radojka M., Tonda, Margaret, Jorga, Karin, Washington, Carla B.
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
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Journal Article
Model‐informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma
Savic, Radojka M., Green, Michelle L., Jorga, Karin, Zager, Michael, Washington, Carla B.
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2022)
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Journal Article
The Disposition of Saquinavir in Normal and P-glycoprotein Deficient Mice, Rats, and in Cultured Cells
WASHINGTON, C. B, WILTSHIRE, H. R, BLASCHKE, T. F, MAN, M, MOY, T, HARRIS, S. R, WORTH, E, WEIGL, P, LIANG, Z, HALL, D, MARRIOTT, L
Published in Drug metabolism and disposition (01.09.2000)
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Published in Drug metabolism and disposition (01.09.2000)
Journal Article
Effect of simultaneous versus staggered dosing on pharmacokinetic interactions of protease inhibitors
Washington, Carla B, Flexner, Charles, Sheiner, Lewis B, Rosenkranz, Susan L, Segal, Yoninah, Aberg, Judith A, Blaschke, Terrence F
Published in Clinical pharmacology and therapeutics (01.05.2003)
Published in Clinical pharmacology and therapeutics (01.05.2003)
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Journal Article
The Pharmacokinetics (PK) of GBT440 Following Single Doses in Pediatric Patients with Sickle Cell Disease (SCD)
Washington, Carla B, Green, Michelle, Inati, Adlette C., Brown, Clark, Hoppe, Carolyn C, Wang, Winfred, Balaratnam, Ganesh, Dixon, Sandra, Fong, Erica, Hutchaleelaha, Athiwat, Tonda, Margaret E, Lehrer, Josh
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Initial Results from a Cohort in a Phase 2a Study (GBT440-007) Evaluating Adolescents with Sickle Cell Disease Treated with Multiple Doses of GBT440, a HbS Polymerization Inhibitor
Hoppe, Carolyn C, Inati, Adlette C., Brown, Clark, Wang, Winfred, Gordeuk, Victor R., Liem, Robert, Woods, Gerald, Piccone, Connie M., Fong, Erica, Balaratnam, Ganesh, Dixon, Sandy, Tonda, Margaret E, Washington, Carla B, Yaron, Yifah, Lehrer, Josh
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Mechanisms of Nucleobase Transport in Rabbit Choroid Plexus
Washington, Carla B., Giacomini, Kathleen M.
Published in The Journal of biological chemistry (01.09.1995)
Published in The Journal of biological chemistry (01.09.1995)
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Journal Article