Mechanism of eIF6 release from the nascent 60S ribosomal subunit
Weis, Félix, Giudice, Emmanuel, Churcher, Mark, Jin, Li, Hilcenko, Christine, Wong, Chi C, Traynor, David, Kay, Robert R, Warren, Alan J
Published in Nature structural & molecular biology (01.11.2015)
Published in Nature structural & molecular biology (01.11.2015)
Get full text
Journal Article
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B
Zyryanova, Alisa F, Weis, Félix, Faille, Alexandre, Alard, Akeel Abo, Crespillo-Casado, Ana, Sekine, Yusuke, Harding, Heather P, Allen, Felicity, Parts, Leopold, Fromont, Christophe, Fischer, Peter M, Warren, Alan J, Ron, David
Published in Science (American Association for the Advancement of Science) (30.03.2018)
Published in Science (American Association for the Advancement of Science) (30.03.2018)
Get full text
Journal Article
Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects
Lakshminarayan, Ramya, Phillips, Ben P., Binnian, Imogen L., Gomez-Navarro, Natalia, Escudero-Urquijo, Norberto, Warren, Alan J., Miller, Elizabeth A.
Published in Current biology (09.03.2020)
Published in Current biology (09.03.2020)
Get full text
Journal Article
Defective ribosome assembly in Shwachman-Diamond syndrome
Wong, Chi C., Traynor, David, Basse, Nicolas, Kay, Robert R., Warren, Alan J.
Published in Blood (20.10.2011)
Published in Blood (20.10.2011)
Get full text
Journal Article
eIF6 rebinding dynamically couples ribosome maturation and translation
Jaako, Pekka, Faille, Alexandre, Tan, Shengjiang, Wong, Chi C, Escudero-Urquijo, Norberto, Castro-Hartmann, Pablo, Wright, Penny, Hilcenko, Christine, Adams, David J, Warren, Alan J
Published in Nature communications (23.03.2022)
Published in Nature communications (23.03.2022)
Get full text
Journal Article
A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit
Rebelo-Guiomar, Pedro, Pellegrino, Simone, Dent, Kyle C, Sas-Chen, Aldema, Miller-Fleming, Leonor, Garone, Caterina, Van Haute, Lindsey, Rogan, Jack F, Dinan, Adam, Firth, Andrew E, Andrews, Byron, Whitworth, Alexander J, Schwartz, Schraga, Warren, Alan J, Minczuk, Michal
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
Get full text
Journal Article
Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold
Gordon, Jacob, Chapus, Fleur L, Viverette, Elizabeth G, Williams, Jason G, Deterding, Leesa J, Krahn, Juno M, Borgnia, Mario J, Rodriguez, Joseph, Warren, Alan J, Stanley, Robin E
Published in Nature communications (09.11.2022)
Published in Nature communications (09.11.2022)
Get full text
Journal Article
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome
Finch, Andrew J, Hilcenko, Christine, Basse, Nicolas, Drynan, Lesley F, Goyenechea, Beatriz, Menne, Tobias F, González Fernández, Africa, Simpson, Paul, D'Santos, Clive S, Arends, Mark J, Donadieu, Jean, Bellanné-Chantelot, Christine, Costanzo, Michael, Boone, Charles, McKenzie, Andrew N, Freund, Stefan M V, Warren, Alan J
Published in Genes & development (01.05.2011)
Published in Genes & development (01.05.2011)
Get full text
Journal Article
Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor
de Jonge, Janeska J., Graw, Andreas, Kargas, Vasileios, Batters, Christopher, Montanarella, Antonino F., O’Loughlin, Tom, Johnson, Chloe, Arden, Susan D., Warren, Alan J., Geeves, Michael A., Kendrick-Jones, John, Zaccai, Nathan R., Kröss, Markus, Veigel, Claudia, Buss, Folma
Published in Nature communications (07.08.2024)
Published in Nature communications (07.08.2024)
Get full text
Journal Article
Convergent somatic evolution commences in utero in a germline ribosomopathy
Machado, Heather E, Øbro, Nina F, Williams, Nicholas, Tan, Shengjiang, Boukerrou, Ahmed Z, Davies, Megan, Belmonte, Miriam, Mitchell, Emily, Baxter, E Joanna, Mende, Nicole, Clay, Anna, Ancliff, Philip, Köglmeier, Jutta, Killick, Sally B, Kulasekararaj, Austin, Meyer, Stefan, Laurenti, Elisa, Campbell, Peter J, Kent, David G, Nangalia, Jyoti, Warren, Alan J
Published in Nature communications (22.08.2023)
Published in Nature communications (22.08.2023)
Get full text
Journal Article
The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast
Tonkin, Louise M, Brost, Renée L, Menne, Tobias F, Warren, Alan J, Ancliff, Philip J, Costanzo, Michael, Sánchez-Puig, Nuria, Goyenechea, Beatriz, Boone, Charles, Wong, Chi C
Published in Nature genetics (01.04.2007)
Published in Nature genetics (01.04.2007)
Get full text
Journal Article
Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies
McKerrell, Thomas, Moreno, Thaidy, Ponstingl, Hannes, Bolli, Niccolo, Dias, João M.L., Tischler, German, Colonna, Vincenza, Manasse, Bridget, Bench, Anthony, Bloxham, David, Herman, Bram, Fletcher, Danielle, Park, Naomi, Quail, Michael A., Manes, Nicla, Hodkinson, Clare, Baxter, Joanna, Sierra, Jorge, Foukaneli, Theodora, Warren, Alan J., Chi, Jianxiang, Costeas, Paul, Rad, Roland, Huntly, Brian, Grove, Carolyn, Ning, Zemin, Tyler-Smith, Chris, Varela, Ignacio, Scott, Mike, Nomdedeu, Josep, Mustonen, Ville, Vassiliou, George S.
Published in Blood (07.07.2016)
Published in Blood (07.07.2016)
Get full text
Journal Article
The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish
Bielczyk-Maczyńska, Ewa, Lam Hung, Laure, Ferreira, Lauren, Fleischmann, Tobias, Weis, Félix, Fernández-Pevida, Antonio, Harvey, Steven A, Wali, Neha, Warren, Alan J, Barroso, Inês, Stemple, Derek L, Cvejic, Ana
Published in PLoS genetics (01.12.2015)
Published in PLoS genetics (01.12.2015)
Get full text
Journal Article
The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet‐INNOCHRON COST Action
Fioredda, Francesca, Skokowa, Julia, Tamary, Hannah, Spanoudakis, Michail, Farruggia, Piero, Almeida, Antonio, Guardo, Daniela, Höglund, Petter, Newburger, Peter E., Palmblad, Jan, Touw, Ivo P., Zeidler, Cornelia, Warren, Alan J., Dale, David C., Welte, Karl, Dufour, Carlo, Papadaki, Helen A.
Published in HemaSphere (01.04.2023)
Published in HemaSphere (01.04.2023)
Get full text
Journal Article
Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias
Cantilena, Sandra, Gasparoli, Luca, Pal, Deepali, Heidenreich, Olaf, Klusmann, Jan‐Henning, Martens, Joost H. A., Faille, Alexandre, Warren, Alan J., Karsa, Mawar, Pandher, Ruby, Somers, Klaartje, Williams, Owen, de Boer, Jasper
Published in Clinical and translational medicine (01.06.2022)
Published in Clinical and translational medicine (01.06.2022)
Get full text
Journal Article