Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution
Dietzen, Michelle, Zhai, Haoran, Lucas, Olivia, Pich, Oriol, Barrington, Christopher, Lu, Wei-Ting, Ward, Sophia, Guo, Yanping, Hynds, Robert E, Zaccaria, Simone, Swanton, Charles, McGranahan, Nicholas, Kanu, Nnennaya
Published in Nature communications (18.07.2024)
Published in Nature communications (18.07.2024)
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A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement
BOWNE, Sara J, HUMPHRIES, Marian M, FULTON, Robert S, SODERGREN, Erica J, ALLMAN, Denis, MILLINGTON-WARD, Sophia, PALFI, Arpad, MCKEE, Alex, BLANTON, Susan H, SLIFER, Susan, KONIDARI, Loanna, FARRAR, G. Jane, SULLIVAN, Lori S, DAIGER, Stephen P, HUMPHRIES, Peter, KENNA, Paul F, TAM, Lawrence Cs, KIANG, Anna S, CAMPBELL, Matthew, WEINSTOCK, George M, KOBOLDT, Daniel C, LI DING
Published in European journal of human genetics : EJHG (01.10.2011)
Published in European journal of human genetics : EJHG (01.10.2011)
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AAV‐mediated gene therapy improving mitochondrial function provides benefit in age‐related macular degeneration models
Millington‐Ward, Sophia, Chadderton, Naomi, Finnegan, Laura K., Post, Iris J.M., Carrigan, Matthew, Gardiner, Tom, Peixoto, Elisa, Maloney, Daniel, Humphries, Marian M., Stitt, Alan, Léveillard, Thierry, Humphries, Pete, Kenna, Paul F., Palfi, Arpad, Farrar, G. Jane
Published in Clinical and translational medicine (01.08.2022)
Published in Clinical and translational medicine (01.08.2022)
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SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration
Finnegan, Laura K, Chadderton, Naomi, Kenna, Paul F, Palfi, Arpad, Carty, Michael, Bowie, Andrew G, Millington-Ward, Sophia, Farrar, G Jane
Published in International journal of molecular sciences (30.01.2022)
Published in International journal of molecular sciences (30.01.2022)
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AAV-NDI1 Therapy Provides Significant Benefit to Murine and Cellular Models of Glaucoma
Millington-Ward, Sophia, Palfi, Arpad, Shortall, Ciara, Finnegan, Laura K, Bargroff, Ethan, Post, Iris J M, Maguire, John, Irnaten, Mustapha, Colm O′Brien, Kenna, Paul F, Chadderton, Naomi, Farrar, G Jane
Published in International journal of molecular sciences (15.08.2024)
Published in International journal of molecular sciences (15.08.2024)
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Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa
Millington-Ward, Sophia, Chadderton, Naomi, O'Reilly, Mary, Palfi, Arpad, Goldmann, Tobias, Kilty, Claire, Humphries, Marian, Wolfrum, Uwe, Bennett, Jean, Humphries, Peter, Kenna, Paul F, Farrar, G Jane
Published in Molecular therapy (01.04.2011)
Published in Molecular therapy (01.04.2011)
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RPE-Directed Gene Therapy Improves Mitochondrial Function in Murine Dry AMD Models
Millington-Ward, Sophia, Chadderton, Naomi, Finnegan, Laura K, Post, Iris J M, Carrigan, Matthew, Nixon, Rachel, Humphries, Marian M, Humphries, Pete, Kenna, Paul F, Palfi, Arpad, Farrar, G Jane
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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AAV-PHP.eB transduces both the inner and outer retina with high efficacy in mice
Palfi, Arpad, Chadderton, Naomi, Millington-Ward, Sophia, Post, Iris, Humphries, Pete, Kenna, Paul F., Farrar, G. Jane
Published in Molecular therapy. Methods & clinical development (09.06.2022)
Published in Molecular therapy. Methods & clinical development (09.06.2022)
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Optimized OPA1 Isoforms 1 and 7 Provide Therapeutic Benefit in Models of Mitochondrial Dysfunction
Maloney, Daniel M, Chadderton, Naomi, Millington-Ward, Sophia, Palfi, Arpad, Shortall, Ciara, O'Byrne, James J, Cassidy, Lorraine, Keegan, David, Humphries, Peter, Kenna, Paul, Farrar, Gwyneth Jane
Published in Frontiers in neuroscience (26.11.2020)
Published in Frontiers in neuroscience (26.11.2020)
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AAV-Delivered Tulp1 Supplementation Therapy Targeting Photoreceptors Provides Minimal Benefit in Tulp1−/− Retinas
Palfi, Arpad, Yesmambetov, Adlet, Millington-Ward, Sophia, Shortall, Ciara, Humphries, Pete, Kenna, Paul F., Chadderton, Naomi, Farrar, G. Jane
Published in Frontiers in neuroscience (27.08.2020)
Published in Frontiers in neuroscience (27.08.2020)
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Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction
Chadderton, Naomi, Palfi, Arpad, Maloney, Daniel M, Carrigan, Matthew, Finnegan, Laura K, Hanlon, Killian S, Shortall, Ciara, O'Reilly, Mary, Humphries, Peter, Cassidy, Lorraine, Kenna, Paul F, Millington-Ward, Sophia, Farrar, G Jane
Published in Pharmaceutics (18.01.2023)
Published in Pharmaceutics (18.01.2023)
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RNAi-based suppression and replacement of rds-peripherin in retinal organotypic culture
Palfi, Arpad, Ader, Marius, Kiang, Anna-Sophia, Millington-Ward, Sophia, Clark, Gerry, O'Reilly, Mary, McMahon, Helena P., Kenna, Paul F., Humphries, Peter, Farrar, G. Jane
Published in Human mutation (01.03.2006)
Published in Human mutation (01.03.2006)
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Development of strategies for conditional RNA interference
Allen, Danny, Kenna, Paul F., Palfi, Arpad, McMahon, Helena P., Millington-Ward, Sophia, O'Reilly, Mary, Humphries, Pete, Farrar, G. Jane
Published in The journal of gene medicine (01.04.2007)
Published in The journal of gene medicine (01.04.2007)
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