5-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)
Witherington, Jason, Bordas, Vincent, Garland, Stephen L, Hickey, Deirdre M.B, Ife, Robert J, Liddle, John, Saunders, Martin, Smith, David G, Ward, Robert W
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
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6-Aryl-pyrazolo[3,4- b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)
Witherington, Jason, Bordas, Vincent, Gaiba, Alessandra, Garton, Neil S., Naylor, Antoinette, Rawlings, Anthony D., Slingsby, Brian P., Smith, David G., Takle, Andrew K., Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
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Journal Article
3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
Smith, David G., Buffet, Marianne, Fenwick, Ashley E., Haigh, David, Ife, Robert J., Saunders, Martin, Slingsby, Brian P., Stacey, Rachel, Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
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Journal Article
6-Heteroaryl-pyrazolo[3,4- b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
Witherington, Jason, Bordas, Vincent, Gaiba, Alessandra, Naylor, Antoinette, Rawlings, Anthony D., Slingsby, Brian P., Smith, David G., Takle, Andrew K., Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
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Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition
Skidmore, John, Atcha, Zeenat, Boucherat, Emmanuelle, Castelletti, Laura, Chen, Deborah W., Coppo, Frank T., Cutler, Leanne, Dunsdon, Rachel M., Heath, Bronagh M., Hutchings, Rio, Hurst, David N., Javed, Sahar, Martin, Samuel, Maskell, Emma S.L., Norton, David, Pemberton, Darrel J., Redshaw, Sally, Rutter, Richard, Sehmi, Sanjeet S., Scoccitti, Tiziana, Temple, Hannah E., Theobald, Pam, Ward, Robert W., Wilson, David M.
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
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Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor
Witherington, Jason, Abberley, Lee, Bellenie, Benjamin R., Boatman, Rio, Collis, Katharine, Dean, David K., Gaiba, Alessandra, Paul King, N., Shuker, Nicola, Steadman, Jon G.A., Takle, Andrew K., Sanger, Gareth, Butler, Sharon, McKay, Fiona, Muir, Alison, Winborn, Kim, Ward, Robert W., Heightman, Tom D.
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article
Pyridone derivatives as potent and selective VLA-4 integrin antagonists
Witherington, Jason, Bordas, Vincent, Gaiba, Alessandra, Green, Phil M., Naylor, Antoinette, Parr, Nigel, Smith, David G., Takle, Andrew K., Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Journal Article
Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists
Witherington, Jason, Blaney, Emma L., Bordas, Vincent, Elliott, Richard L., Gaiba, Alessandra, Garton, Neil, Green, Philip M., Naylor, Antoinette, Smith, David G., Spalding, David J., Takle, Andrew K., Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
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Steric acceleration of an uncatalysed ene reaction at room temperature
Choony, N, Sammes, PG, Smith, G, Ward, RW
Published in Chemical communications (Cambridge, England) (21.10.2001)
Published in Chemical communications (Cambridge, England) (21.10.2001)
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Journal Article
5-Aryl-pyrazolo[3,4- b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3)
Witherington, Jason, Bordas, Vincent, Haigh, David, Hickey, Deirdre M.B, Ife, Robert J, Rawlings, Anthony D, Slingsby, Brian P, Smith, David G, Ward, Robert W
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
Published in Bioorganic & medicinal chemistry letters (05.05.2003)
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Synthesis of novel N-phosphonoalkyl dipeptide inhibitors of human collagenase
Bird, John, De Mello, Rachel C, Harper, Gregory P, Hunter, David J, Karran, Eric H, Markwell, Roger E, Miles-Williams, Anette J, Rahman, Shahzad S, Ward, Robert W
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
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A powerful aqueous solvent effect in an intramolecular Diels–Alder cyclisation
Kuhnert, Nikolai, Sammes, Peter G, Smith, Graham, Ward, Robert W
Published in Journal of chemical research (01.09.2004)
Published in Journal of chemical research (01.09.2004)
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Journal Article
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
Coghlan, Matthew P, Culbert, Ainsley A, Cross, Darren AE, Corcoran, Stacey L, Yates, John W, Pearce, Nigel J, Rausch, Oliver L, Murphy, Gregory J, Carter, Paul S, Roxbee Cox, Lynne, Mills, David, Brown, Murray J, Haigh, David, Ward, Robert W, Smith, David G, Murray, Kenneth J, Reith, Alastair D, Holder, Julie C
Published in Chemistry & biology (01.10.2000)
Published in Chemistry & biology (01.10.2000)
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On the steric acceleration of ene reactions
Choony, N, Kuhnert, N, Sammes, PG, Smith, G, Ward, RW
Published in Perkin 1 : an international journal of organic and bio-organic chemistry (23.08.2002)
Published in Perkin 1 : an international journal of organic and bio-organic chemistry (23.08.2002)
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A National Survey of Burnout and Depression Among Fellows Training in Pulmonary and Critical Care Medicine
Sharp, Michelle, Burkart, Kristin M., Adelman, Mark H., Ashton, Rendell W., Daugherty Biddison, Lee, Bosslet, Gabriel T., Doyle, Stephen T., Eckmann, Thomas, Khurram S. Khan, Malik M., Lenz, Peter H., McCallister, Jennifer W., O’Toole, Jacqueline, Rand, Cynthia S., Riekert, Kristin A., Soffler, Morgan I., Winter, Gretchen R., Zaeh, Sandra, Eakin, Michelle N., Arabelovic, Senada, Baer, Alan, Greene, Jerome L., Baker, Matthew C., Bloch, Donald, Cohen, Philip, Danielides, Stamatina J., Danila, Maria, Dellaripa, Paul F., Lawrence Ford, Theresa, Fox, Robert I., Grader-Beck, Thomas, Johr, Chadwick R., Kassan, Stuart, Katsumoto, Tamiko, Kontzias, Apostolos, Koons, Kirsten, Kyttaris, Vasileios C., Lewis, Janet, Lieberman, Scott M., McCoy, Sara S., Niewold, Timothy, Noaiseh, Ghaith, Osborn, Thomas G., Culpepper Pace, Schartess, Peredo-Wende, Ruben, Pillemer, Stanley, Neal Roberts, W., Rosenstein, Elliot, Sachdev, Amit, Sandorfi, Nora, Segal, Barbara, Siva, Chokkalingam, Small, Daniel, Spiera, Robert F., Topilow, James, Treadwell, Edward L., Vivino, Frederick B., Volkmann, Elizabeth, Wallace, Daniel J., Zashin, Scott, Gupta Argula, Rahul, Barney, Joseph, Burger, Charles D., Downey, Gregory P., Gagermeier, James, Helmers, Richard A., Hewlett, Justin C., Keith, Rebecca C., Koslow, Matthew, Kotloff, Robert, Krishna, Rachana, Luckhardt, Tracy R., Robinson, Keith, Ryu, Jay H., Shifren, Adrian, Staton, Gerald, Swigris, Jeff, Vassallo, Robert, Veraldi, Kristen L., Ward, Robert W., Bromet, Evelyn J., Dale, Jeanne, Furlong, Judith A., Neall, Kerry L., Petruzzi, Lynn M., Schafer, Sarah, Kukla, Heidi
Published in Chest (01.02.2021)
Published in Chest (01.02.2021)
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