State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors
Sheng, Chunquan, Dong, Guoqiang, Miao, Zhenyuan, Zhang, Wannian, Wang, Wei
Published in Chemical Society reviews (21.11.2015)
Published in Chemical Society reviews (21.11.2015)
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Inhibitor of Apoptosis Protein (IAP) Antagonists in Anticancer Agent Discovery: Current Status and Perspectives
Cong, Hui, Xu, Lijuan, Wu, Yougen, Qu, Zhuo, Bian, Tengfei, Zhang, Wannian, Xing, Chengguo, Zhuang, Chunlin
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Rapid Identification of Keap1–Nrf2 Small-Molecule Inhibitors through Structure-Based Virtual Screening and Hit-Based Substructure Search
Zhuang, Chunlin, Narayanapillai, Sreekanth, Zhang, Wannian, Sham, Yuk Yin, Xing, Chengguo
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Journal Article
New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations
Dong, Guoqiang, Wang, Shengzheng, Miao, Zhenyuan, Yao, Jianzhong, Zhang, Yongqiang, Guo, Zizhao, Zhang, Wannian, Sheng, Chunquan
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Journal Article
Mechanism and Improved Dissolution of Glycyrrhetinic Acid Solid Dispersion by Alkalizers
Dong, Luning, Mai, Yaping, Liu, Qiang, Zhang, Wannian, Yang, Jianhong
Published in Pharmaceutics (20.01.2020)
Published in Pharmaceutics (20.01.2020)
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Journal Article
Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy
Zhu, Jing, Xin, Meng, Xu, Congcong, He, Yuan, Zhang, Wannian, Wang, Zhibin, Zhuang, Chunlin
Published in Acta pharmaceutica Sinica. B (01.10.2021)
Published in Acta pharmaceutica Sinica. B (01.10.2021)
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Journal Article
Structure-based optimizations of a necroptosis inhibitor (SZM594) as novel protective agents of acute lung injury
Xu, Lijuan, Tu, Ye, Li, Jiao, Zhang, Wannian, Wang, Zhibin, Zhuang, Chunlin, Xue, Lei
Published in Chinese chemical letters (01.05.2022)
Published in Chinese chemical letters (01.05.2022)
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Pharmacokinetic, Tissue Distribution, Metabolite, and Toxicity Evaluation of the Matrine Derivative, (6aS, 10S, 11aR, 11bR, 11cS)-10-Methylaminododecahydro-3a, 7a-Diaza-benzo (de) Anthracene-8-thione
Li, Liuyan, Lu, Fangfang, Ding, Shuqin, Wang, Xiaoying, Wang, Weibiao, Zhang, Wannian, Xu, Weiheng, Zhuang, Chunlin, Miao, Zhenyuan, Ma, Xueqin
Published in Molecules (Basel, Switzerland) (06.01.2024)
Published in Molecules (Basel, Switzerland) (06.01.2024)
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Radiosensitization of human pancreatic cancer by piperlongumine analogues
Ma, Hao, Wu, Yuelin, Zhang, Wannian, Zhang, Huojun, Miao, Zhenyuan, Zhuang, Chunlin
Published in Chinese chemical letters (01.03.2021)
Published in Chinese chemical letters (01.03.2021)
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Journal Article
Dual NAMPT/HDAC Inhibitors as a New Strategy for Multitargeting Antitumor Drug Discovery
Chen, Wei, Dong, Guoqiang, Wu, Ying, Zhang, Wannian, Miao, Chaoyu, Sheng, Chunquan
Published in ACS medicinal chemistry letters (11.01.2018)
Published in ACS medicinal chemistry letters (11.01.2018)
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Journal Article
Preparation and characterization of wet-milled cyclovirobuxine D nanosuspensions
Han, Tianyan, Yong, Jinjiao, Liu, Qiang, Gu, Xiangshuai, Zhang, Wannian, Yang, Jianhong
Published in Journal of thermal analysis and calorimetry (01.02.2020)
Published in Journal of thermal analysis and calorimetry (01.02.2020)
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Journal Article
Chlorin p6‑Based Water-Soluble Amino Acid Derivatives as Potent Photosensitizers for Photodynamic Therapy
Meng, Zhi, Yu, Bin, Han, Guiyan, Liu, Minghui, Shan, Bin, Dong, Guoqiang, Miao, Zhenyuan, Jia, Ningyang, Tan, Zou, Li, Buhong, Zhang, Wannian, Zhu, Haiying, Sheng, Chunquan, Yao, Jianzhong
Published in Journal of medicinal chemistry (26.05.2016)
Published in Journal of medicinal chemistry (26.05.2016)
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JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis
Li, Zhenyang, Zhou, Ye, Jia, Kaiwei, Yang, Yingyun, Zhang, Liyuan, Wang, Suyuan, Dong, Yue, Wang, Mu, Li, Yunhui, Lu, Shan, Zhang, Wannian, Zhang, Luxin, Fan, Yiwen, Zhang, Dingji, Li, Nan, Yu, Yizhi, Cao, Xuetao, Hou, Jin
Published in Journal of hematology and oncology (04.11.2022)
Published in Journal of hematology and oncology (04.11.2022)
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Journal Article
New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors
Sheng, Chunquan, Miao, Zhenyuan, Zhang, Wannian
Published in Current medicinal chemistry (01.10.2011)
Published in Current medicinal chemistry (01.10.2011)
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Journal Article
A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease
Sun, Yi, Xu, Lijuan, Zheng, Dongpeng, Wang, Jue, Liu, Guodong, Mo, Zixin, Liu, Chao, Zhang, Wannian, Yu, Jianqiang, Xing, Chengguo, He, Ling, Zhuang, Chunlin
Published in Redox biology (01.08.2023)
Published in Redox biology (01.08.2023)
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Journal Article
Design, synthesis and antifungal activity of novel triazole derivatives containing substituted 1,2,3-triazole-piperdine side chains
Jiang, Zhigan, Gu, Julin, Wang, Chen, Wang, Shengzheng, Liu, Na, Jiang, Yan, Dong, Guoqiang, Wang, Yan, Liu, Yang, Yao, Jianzhong, Miao, Zhenyuan, Zhang, Wannian, Sheng, Chunquan
Published in European journal of medicinal chemistry (23.07.2014)
Published in European journal of medicinal chemistry (23.07.2014)
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Journal Article
Discovery of simplified sampangine derivatives as novel fungal biofilm inhibitors
Liu, Na, Zhong, Hua, Tu, Jie, Jiang, Zhigan, Jiang, Yanjuan, Jiang, Yan, Jiang, Yuanying, Li, Jian, Zhang, Wannian, Wang, Yan, Sheng, Chunquan
Published in European journal of medicinal chemistry (01.01.2018)
Published in European journal of medicinal chemistry (01.01.2018)
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