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FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity
Wang, Xiaoxin X., Wang, Dong, Luo, Yuhuan, Myakala, Komuraiah, Dobrinskikh, Evgenia, Rosenberg, Avi Z., Levi, Jonathan, Kopp, Jeffrey B., Field, Amanda, Hill, Ashley, Lucia, Scott, Qiu, Liru, Jiang, Tao, Peng, Yingqiong, Orlicky, David, Garcia, Gabriel, Herman-Edelstein, Michal, D’Agati, Vivette, Henriksen, Kammi, Adorini, Luciano, Pruzanski, Mark, Xie, Cen, Krausz, Kristopher W., Gonzalez, Frank J., Ranjit, Suman, Dvornikov, Alexander, Gratton, Enrico, Levi, Moshe
Published in Journal of the American Society of Nephrology (01.01.2018)
Published in Journal of the American Society of Nephrology (01.01.2018)
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G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
Wang, Xiaoxin X., Edelstein, Michal Herman, Gafter, Uzi, Qiu, Liru, Luo, Yuhuan, Dobrinskikh, Evgenia, Lucia, Scott, Adorini, Luciano, D’Agati, Vivette D., Levi, Jonathan, Rosenberg, Avi, Kopp, Jeffrey B., Gius, David R., Saleem, Moin A., Levi, Moshe
Published in Journal of the American Society of Nephrology (01.05.2016)
Published in Journal of the American Society of Nephrology (01.05.2016)
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Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease
McMahan, Rachel H., Wang, Xiaoxin X., Cheng, Lin Ling, Krisko, Tibor, Smith, Maxwell, El Kasmi, Karim, Pruzanski, Mark, Adorini, Luciano, Golden-Mason, Lucy, Levi, Moshe, Rosen, Hugo R.
Published in The Journal of biological chemistry (26.04.2013)
Published in The Journal of biological chemistry (26.04.2013)
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Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
Rizzo, Giovanni, Passeri, Daniela, De Franco, Francesca, Ciaccioli, Gianmario, Donadio, Loredana, Rizzo, Giorgia, Orlandi, Stefano, Sadeghpour, Bahman, Wang, Xiaoxin X., Jiang, Tao, Levi, Moshe, Pruzanski, Mark, Adorini, Luciano
Published in Molecular pharmacology (01.10.2010)
Published in Molecular pharmacology (01.10.2010)
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An in Situ Atlas of Mitochondrial DNA in Mammalian Tissues Reveals High Content in Stem and Proliferative Compartments
Chen, Jiayu, Zheng, Qizhi, Peiffer, Lauren B., Hicks, Jessica L., Haffner, Michael C., Rosenberg, Avi Z., Levi, Moshe, Wang, Xiaoxin X., Ozbek, Busra, Baena-Del Valle, Javier, Yegnasubramanian, Srinivasan, De Marzo, Angelo M.
Published in The American journal of pathology (01.07.2020)
Published in The American journal of pathology (01.07.2020)
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Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model
Wang, Xiaoxin X., Jiang, Tao, Shen, Yan, Caldas, Yupanqui, Miyazaki-Anzai, Shinobu, Santamaria, Hannah, Urbanek, Cydney, Solis, Nathaniel, Scherzer, Pnina, Lewis, Linda, Gonzalez, Frank J., Adorini, Luciano, Pruzanski, Mark, Kopp, Jeffrey B., Verlander, Jill W., Levi, Moshe
Published in Diabetes (New York, N.Y.) (01.11.2010)
Published in Diabetes (New York, N.Y.) (01.11.2010)
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The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria
Wang, Xiaoxin X., Jiang, Tao, Shen, Yan, Adorini, Luciano, Pruzanski, Mark, Gonzalez, Frank J., Scherzer, Pnina, Lewis, Linda, Miyazaki-Anzai, Shinobu, Levi, Moshe
Published in American Journal of Physiology - Renal Physiology (01.12.2009)
Published in American Journal of Physiology - Renal Physiology (01.12.2009)
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Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice
Jonscher, Karen R, Stewart, Michael S, Alfonso-Garcia, Alba, DeFelice, Brian C, Wang, Xiaoxin X, Luo, Yuhuan, Levi, Moshe, Heerwagen, Margaret J R, Janssen, Rachel C, de la Houssaye, Becky A, Wiitala, Ellen, Florey, Garrett, Jonscher, Raleigh L, Potma, Eric O, Fiehn, Oliver, Friedman, Jacob E
Published in The FASEB journal (01.04.2017)
Published in The FASEB journal (01.04.2017)
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Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy
Jiang, Tao, Wang, Xiaoxin X., Scherzer, Pnina, Wilson, Paul, Tallman, James, Takahashi, Hideaki, Li, Jinping, Iwahashi, Mieko, Sutherland, Eileen, Arend, Lois, Levi, Moshe
Published in Diabetes (New York, N.Y.) (01.10.2007)
Published in Diabetes (New York, N.Y.) (01.10.2007)
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Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate
Giral, Hector, Caldas, Yupanqui, Sutherland, Eileen, Wilson, Paul, Breusegem, Sophia, Barry, Nicholas, Blaine, Judith, Jiang, Tao, Wang, Xiaoxin X., Levi, Moshe
Published in American Journal of Physiology - Renal Physiology (01.11.2009)
Published in American Journal of Physiology - Renal Physiology (01.11.2009)
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PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
Yoshida, Teruhiko, Latt, Khun Zaw, Rosenberg, Avi Z, Santo, Briana A, Myakala, Komuraiah, Ishimoto, Yu, Zhao, Yongmei, Shrivastav, Shashi, Jones, Bryce A, Yang, Xiaoping, Wang, Xiaoxin X, Tutino, Vincent M, Sarder, Pinaki, Levi, Moshe, Okamoto, Koji, Winkler, Cheryl A, Kopp, Jeffrey B
Published in eLife (29.08.2024)
Published in eLife (29.08.2024)
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Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism
Wang, Xiaoxin X., Jiang, Tao, Shen, Yan, Santamaria, Hannah, Solis, Nathaniel, Arbeeny, Cynthia, Levi, Moshe
Published in American journal of physiology. Renal physiology (01.03.2011)
Published in American journal of physiology. Renal physiology (01.03.2011)
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The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor
Hammer, Sandra S., Beli, Eleni, Kady, Nermin, Wang, Qi, Wood, Kiana, Lydic, Todd A., Malek, Goldis, Saban, Daniel R., Wang, Xiaoxin X., Hazra, Sugata, Levi, Moshe, Busik, Julia V., Grant, Maria B.
Published in EBioMedicine (01.08.2017)
Published in EBioMedicine (01.08.2017)
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Characterizing the Retinal Phenotype in the High-Fat Diet and Western Diet Mouse Models of Prediabetes
Asare-Bediako, Bright, Noothi, Sunil, Li Calzi, Sergio, Athmanathan, Baskaran, Vieira, Cristiano, Adu-Agyeiwaah, Yvonne, Dupont, Mariana, Jones, Bryce, Wang, Xiaoxin, Chakraborty, Dibyendu, Levi, Moshe, Nagareddy, Prabhakara, Grant, Maria
Published in Cells (Basel, Switzerland) (18.02.2020)
Published in Cells (Basel, Switzerland) (18.02.2020)
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Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment
Myakala, Komuraiah, Jones, Bryce A., Wang, Xiaoxin X., Levi, Moshe
Published in American journal of physiology. Renal physiology (01.06.2021)
Published in American journal of physiology. Renal physiology (01.06.2021)
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SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy: SGLT2 PROTEIN INHIBITION DECREASES RENAL LIPID ACCUMULATION, INFLAMMATION, AND THE DEVELOPMENT OF NEPHROPATHY IN DIABETIC MICE
Wang, Xiaoxin X, Levi, Jonathan, Luo, Yuhuan, Myakala, Komuraiah, Herman-Edelstein, Michal, Qiu, Liru, Wang, Dong, Peng, Yingqiong, Grenz, Almut, Lucia, Scott, Dobrinskikh, Evgenia, D'Agati, Vivette D, Koepsell, Hermann, Kopp, Jeffrey B, Rosenberg, Avi Z, Levi, Moshe
Published in The Journal of biological chemistry (31.03.2017)
Published in The Journal of biological chemistry (31.03.2017)
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PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone
Laurino, Lisandro, Wang, Xiaoxin X, de la Houssaye, Becky A, Sosa, Lucas, Dupraz, Sebastian, Cáceres, Alfredo, Pfenninger, Karl H, Quiroga, Santiago
Published in Journal of cell science (15.08.2005)
Published in Journal of cell science (15.08.2005)
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Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice
Beli, Eleni, Yan, Yuanqing, Moldovan, Leni, Vieira, Cristiano P., Gao, Ruli, Duan, Yaqian, Prasad, Ram, Bhatwadekar, Ashay, White, Fletcher A., Townsend, Steven D., Chan, Luisa, Ryan, Caitlin N., Morton, Daniel, Moldovan, Emil G., Chu, Fang-I, Oudit, Gavin Y., Derendorf, Hartmut, Adorini, Luciano, Wang, Xiaoxin X., Evans-Molina, Carmella, Mirmira, Raghavendra G., Boulton, Michael E., Yoder, Mervin C., Li, Qiuhong, Levi, Moshe, Busik, Julia V., Grant, Maria B.
Published in Diabetes (New York, N.Y.) (01.09.2018)
Published in Diabetes (New York, N.Y.) (01.09.2018)
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A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice
Wang, Xiaoxin X., Luo, Yuhuan, Wang, Dong, Adorini, Luciano, Pruzanski, Mark, Dobrinskikh, Evgenia, Levi, Moshe
Published in The Journal of biological chemistry (21.07.2017)
Published in The Journal of biological chemistry (21.07.2017)
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Role of Nuclear Receptors, Lipid Metabolism, and Mitochondrial Function in the Pathogenesis of Diabetic Kidney Disease
Hughes, Eleni, Wang, Xiaoxin X., Sabol, Lily, Barton, Keely, Hegde, Sujit, Myakala, Komuraiah, Krawczyk, Ewa, Rosenberg, Avi Z., Levi, Moshe
Published in American journal of physiology. Renal physiology (19.08.2025)
Published in American journal of physiology. Renal physiology (19.08.2025)
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