Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models
Gavine, Paul R., Ren, Yongxin, Han, Lu, Lv, Jing, Fan, Shiming, Zhang, Wei, Xu, Wen, Liu, Yuan Jie, Zhang, Tianwei, Fu, Haihua, Yu, Yongjuan, Wang, Huiying, Xu, Shirlian, Zhou, Feng, Su, Xinying, Yin, XiaoLu, Xie, Liang, Wang, Linfang, Qing, Weiguo, Jiao, Longxian, Su, Weiguo, Wang, Q. May
Published in Molecular oncology (01.01.2015)
Published in Molecular oncology (01.01.2015)
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The IKK NF-κB system: a treasure trove for drug development
Karin, Michael, Yamamoto, Yumi, Wang, Q. May
Published in Nature reviews. Drug discovery (01.01.2004)
Published in Nature reviews. Drug discovery (01.01.2004)
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Journal Article
Oligomerization and Cooperative RNA Synthesis Activity of Hepatitis C Virus RNA-Dependent RNA Polymerase
Wang, Q May, Hockman, Michelle A, Staschke, Kirk, Johnson, Robert B, Case, Katharine A, Lu, Jirong, Parsons, Steve, Zhang, Faming, Rathnachalam, Radhakrishnan, Kirkegaard, Karla, Colacino, Joseph M
Published in Journal of Virology (01.04.2002)
Published in Journal of Virology (01.04.2002)
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Identification of a C-Terminal Regulatory Motif in Hepatitis C Virus RNA-Dependent RNA Polymerase: Structural and Biochemical Analysis
Lévêque, Vincent J.-P., Johnson, Robert B., Parsons, Stephen, Ren, Jianxin, Xie, Congping, Zhang, Faming, Wang, Q. May
Published in Journal of Virology (01.08.2003)
Published in Journal of Virology (01.08.2003)
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Journal Article
Identification and Characterization of a Monofunctional Glycosyltransferase from Staphylococcus aureus
Wang, Q M, Peery, R B, Johnson, R B, Alborn, W E, Yeh, W K, Skatrud, P L
Published in Journal of Bacteriology (01.08.2001)
Published in Journal of Bacteriology (01.08.2001)
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Journal Article
Comparative characterization of two DEAD-box RNA helicases in superfamily II: human translation-initiation factor 4A and hepatitis C virus non-structural protein 3 (NS3) helicase
Du, Mark X, Johnson, Robert B, Sun, Xin-Lai, Staschke, Kirk A, Colacino, Joseph, Wang, Q May
Published in Biochemical journal (01.04.2002)
Published in Biochemical journal (01.04.2002)
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Journal Article
Expression and purification of untagged full-length HCV NS5B RNA-dependent RNA polymerase
May Wang, Q, Johnson, Robert B, Chen, Dayue, Lévêque, Vincent J.-P, Ren, Jianxin, Hockman, Michelle A, Abe, Kenji, Hachisu, Tessho, Kondo, Yutaka, Isaka, Yoshitaka, Sato, Akihiko, Fujiwara, Tamio
Published in Protein expression and purification (01.06.2004)
Published in Protein expression and purification (01.06.2004)
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Journal Article
Dual Inhibition of Human Rhinovirus 2A and 3C Proteases by Homophthalimides
MAY WANG, Q, JOHNSON, R. B, JUNGHEIM, L. N, COHEN, J. D, VILLARREAL, E. C
Published in Antimicrobial Agents and Chemotherapy (01.04.1998)
Published in Antimicrobial Agents and Chemotherapy (01.04.1998)
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Journal Article
Template Requirements for RNA Synthesis by a Recombinant Hepatitis C Virus RNA-Dependent RNA Polymerase
Kao, C C, Yang, X, Kline, A, Wang, Q M, Barket, D, Heinz, B A
Published in Journal of Virology (01.12.2000)
Published in Journal of Virology (01.12.2000)
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Journal Article
P4 and P1′ optimization of bicycloproline P2 bearing tetrapeptidyl α-ketoamides as HCV protease inhibitors
Yip, Yvonne, Victor, Frantz, Lamar, Jason, Johnson, Robert, Wang, Q. May, Glass, John I., Yumibe, Nathan, Wakulchik, Mark, Munroe, John, Chen, Shu-Hui
Published in Bioorganic & medicinal chemistry letters (04.10.2004)
Published in Bioorganic & medicinal chemistry letters (04.10.2004)
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Journal Article
Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor
Yip, Yvonne, Victor, Frantz, Lamar, Jason, Johnson, Robert, Wang, Q.May, Barket, Donna, Glass, John, Jin, Ling, Liu, Lifei, Venable, Daryl, Wakulchik, Mark, Xie, Congping, Heinz, Beverly, Villarreal, Elcira, Colacino, Joe, Yumibe, Nathan, Tebbe, Mark, Munroe, John, Chen, Shu-Hui
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
P4 cap modified tetrapeptidyl α-ketoamides as potent HCV NS3 protease inhibitors
Sun, David X, Liu, Lifei, Heinz, Beverly, Kolykhalov, Alexander, Lamar, Jason, Johnson, Robert B, Wang, Q.May, Yip, Yvonne, Chen, Shu-Hui
Published in Bioorganic & medicinal chemistry letters (16.08.2004)
Published in Bioorganic & medicinal chemistry letters (16.08.2004)
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Journal Article
P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl α-ketoamide based HCV protease inhibitors
Victor, Frantz, Lamar, Jason, Snyder, Nancy, Yip, Yvonne, Guo, Deqi, Yumibe, Nathan, Johnson, Robert B., Wang, Q.May, Glass, John I., Chen, Shu-Hui
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
Synthesis and evaluation of tripeptidyl α-ketoamides as human rhinovirus 3C protease inhibitors
CHEN, Shu-Hui, LAMAR, Jason, VICTOR, Frantz, SNYDER, Nancy, JOHNSON, Robert, HEINZ, Beverly A, WAKULCHIK, Mark, WANG, Q. May
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
Novel P4 truncated tripeptidyl α-ketoamides as HCV protease inhibitors
Lamar, Jason, Victor, Frantz, Snyder, Nancy, Johnson, Robert B., Wang, Q.May, Glass, John I., Chen, Shu-Hui
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
A Kinetic Approach for the Study of Protein Phosphatase-Catalyzed Regulation of Protein Kinase Activity
Wang, Zhi-Xin, Zhou, Bo, Wang, Q. May, Zhang, Zhong-Yin
Published in Biochemistry (Easton) (18.06.2002)
Published in Biochemistry (Easton) (18.06.2002)
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Journal Article
S-Nitrosothiols as novel, reversible inhibitors of human rhinovirus 3C protease
Xian, Ming, Wang, Q.May, Chen, Xinchao, Wang, Kun, Wang, Peng G.
Published in Bioorganic & medicinal chemistry letters (18.09.2000)
Published in Bioorganic & medicinal chemistry letters (18.09.2000)
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