Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies
Zhang, Lin, Yadav, Sandeep, John Wang, Y., Mozziconacci, Olivier, Schӧneich, Christian
Published in Pharmaceutical research (01.02.2018)
Published in Pharmaceutical research (01.02.2018)
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Oxidative Degradation of Polysorbate Surfactants Studied by Liquid Chromatography–Mass Spectrometry
Borisov, Oleg V., Ji, Junyan A., John Wang, Y.
Published in Journal of pharmaceutical sciences (01.03.2015)
Published in Journal of pharmaceutical sciences (01.03.2015)
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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point
Darman, Rachel B., Seiler, Michael, Agrawal, Anant A., Lim, Kian H., Peng, Shouyong, Aird, Daniel, Bailey, Suzanna L., Bhavsar, Erica B., Chan, Betty, Colla, Simona, Corson, Laura, Feala, Jacob, Fekkes, Peter, Ichikawa, Kana, Keaney, Gregg F., Lee, Linda, Kumar, Pavan, Kunii, Kaiko, MacKenzie, Crystal, Matijevic, Mark, Mizui, Yoshiharu, Myint, Khin, Park, Eun Sun, Puyang, Xiaoling, Selvaraj, Anand, Thomas, Michael P., Tsai, Jennifer, Wang, John Y., Warmuth, Markus, Yang, Hui, Zhu, Ping, Garcia-Manero, Guillermo, Furman, Richard R., Yu, Lihua, Smith, Peter G., Buonamici, Silvia
Published in Cell reports (Cambridge) (03.11.2015)
Published in Cell reports (Cambridge) (03.11.2015)
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Light-Induced Histidine Adducts to an IgG1 Molecule Via Oxidized Histidine Residue and the Potential Impact of Polysorbate-20 Concentration
Lei, Ming, Quan, Cynthia, Wang, John. Y., Kao, Yung-Hsiang, Schöneich, Christian
Published in Pharmaceutical research (01.03.2021)
Published in Pharmaceutical research (01.03.2021)
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Effect of Individual Fc Methionine Oxidation on FcRn Binding: Met252 Oxidation Impairs FcRn Binding More Profoundly than Met428 Oxidation
Gao, Xuan, Ji, Junyan A., Veeravalli, Karthik, John Wang, Y., Zhang, Taylor, Mcgreevy, William, Zheng, Kai, Kelley, Robert F., Laird, Michael W., Liu, Jun, Cromwell, Mary
Published in Journal of pharmaceutical sciences (01.02.2015)
Published in Journal of pharmaceutical sciences (01.02.2015)
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Effect of ambient light on IgG1 monoclonal antibodies during drug product processing and development
Sreedhara, Alavattam, Yin, Jian, Joyce, Michael, Lau, Kimberly, Wecksler, Aaron T., Deperalta, Galahad, Yi, Li, John Wang, Y., Kabakoff, Bruce, Kishore, Ravuri S.K.
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2016)
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2016)
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Methionine, tryptophan, and histidine oxidation in a model protein, PTH: Mechanisms and stabilization
Ji, Junyan A., Zhang, Boyan, Cheng, Wilson, Wang, Y. John
Published in Journal of pharmaceutical sciences (01.12.2009)
Published in Journal of pharmaceutical sciences (01.12.2009)
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An Efficient and Rapid Method to Monitor the Oxidative Degradation of Protein Pharmaceuticals: Probing Tyrosine Oxidation with Fluorogenic Derivatization
Bommana, Rupesh, Mozziconacci, Olivier, John Wang, Y., Schöneich, Christian
Published in Pharmaceutical research (01.07.2017)
Published in Pharmaceutical research (01.07.2017)
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Photo-oxidation of IgG1 and Model Peptides: Detection and Analysis of Triply Oxidized His and Trp Side Chain Cleavage Products
Bane, Jessica, Mozziconacci, Olivier, Yi, Li, Wang, Y. John, Sreedhara, Alavattam, Schöneich, Christian
Published in Pharmaceutical research (01.01.2017)
Published in Pharmaceutical research (01.01.2017)
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The Use of a 2,2'-Azobis (2-Amidinopropane) Dihydrochloride Stress Model as an Indicator of Oxidation Susceptibility for Monoclonal Antibodies
Dion, Michelle Z., Wang, Y. John, Bregante, Daniel, Chan, Wayman, Andersen, Nisana, Hilderbrand, Amy, Leiske, Danielle, Salisbury, Cleo M.
Published in Journal of pharmaceutical sciences (01.02.2018)
Published in Journal of pharmaceutical sciences (01.02.2018)
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Effect of Ionic Strength and pH on the Physical and Chemical Stability of a Monoclonal Antibody Antigen-Binding Fragment
Wang, Tingting, Kumru, Ozan S., Yi, Li, John Wang, Y., Zhang, Jennifer, Kim, Jae Hyun, Joshi, Sangeeta B., Russell Middaugh, C., Volkin, David B.
Published in Journal of pharmaceutical sciences (01.08.2013)
Published in Journal of pharmaceutical sciences (01.08.2013)
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Polar Solvents Decrease the Viscosity of High Concentration IgG1 Solutions Through Hydrophobic Solvation and Interaction: Formulation and Biocompatibility Considerations
Kamerzell, Tim J., Pace, Amanda L., Li, Megan, Danilenko, Dimitry M., Mcdowell, Michelle, Gokarn, Yatin R., John Wang, Y.
Published in Journal of pharmaceutical sciences (01.04.2013)
Published in Journal of pharmaceutical sciences (01.04.2013)
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Aspartate Isomerization in the Complementarity-Determining Regions of Two Closely Related Monoclonal Antibodies
Wakankar, Aditya A, Borchardt, Ronald T, Eigenbrot, Charles, Shia, Steven, Wang, Y. John, Shire, Steve J, Liu, Jun L
Published in Biochemistry (Easton) (13.02.2007)
Published in Biochemistry (Easton) (13.02.2007)
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