Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome
Rom, Oren, Liu, Yuhao, Liu, Zhipeng, Zhao, Ying, Wu, Jianfeng, Ghrayeb, Alia, Villacorta, Luis, Fan, Yanbo, Chang, Lin, Wang, Lu, Liu, Cai, Yang, Dongshan, Song, Jun, Rech, Jason C, Guo, Yanhong, Wang, Huilun, Zhao, Guizhen, Liang, Wenying, Koike, Yui, Lu, Haocheng, Koike, Tomonari, Hayek, Tony, Pennathur, Subramaniam, Xi, Chuanwu, Wen, Bo, Sun, Duxin, Garcia-Barrio, Minerva T, Aviram, Michael, Gottlieb, Eyal, Mor, Inbal, Liu, Wanqing, Zhang, Jifeng, Chen, Y Eugene
Published in Science translational medicine (02.12.2020)
Published in Science translational medicine (02.12.2020)
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Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB
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Published in Circulation (New York, N.Y.) (04.08.2020)
Published in Circulation (New York, N.Y.) (04.08.2020)
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Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders
Wang, Huilun H, Lin, Liangguang L, Li, Zexin J, Wei, Xiaoqiong, Askander, Omar, Cappuccio, Gerarda, Hashem, Mais O, Hubert, Laurence, Munnich, Arnold, Alqahtani, Mashael, Pang, Qi, Burmeister, Margit, Lu, You, Poirier, Karine, Besmond, Claude, Sun, Shengyi, Brunetti-Pierri, Nicola, Alkuraya, Fowzan S, Qi, Ling
Published in The Journal of clinical investigation (16.01.2024)
Published in The Journal of clinical investigation (16.01.2024)
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BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis
Zhao, Guizhen, Zhao, Yang, Lu, Haocheng, Chang, Ziyi, Liu, Hongyu, Wang, Huilun, Liang, Wenying, Liu, Yuhao, Zhu, Tianqing, Rom, Oren, Guo, Yanhong, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T, Lin, Jiandie D, Chen, Y Eugene, Zhang, Jifeng
Published in The Journal of clinical investigation (01.11.2022)
Published in The Journal of clinical investigation (01.11.2022)
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Biallelic Cys141Tyr variant of SEL1L is associated with neurodevelopmental disorders, agammaglobulinemia, and premature death
Weis, Denisa, Lin, Liangguang L, Wang, Huilun H, Li, Zexin Jason, Kusikova, Katarina, Ciznar, Peter, Wolf, Hermann M, Leiss-Piller, Alexander, Wang, Zhihong, Wei, Xiaoqiong, Weis, Serge, Skalicka, Katarina, Hrckova, Gabriela, Danisovic, Lubos, Soltysova, Andrea, Yang, Tingxuan T, Feichtinger, René Günther, Mayr, Johannes A, Qi, Ling
Published in The Journal of clinical investigation (16.01.2024)
Published in The Journal of clinical investigation (16.01.2024)
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Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis
Liu, Yuhao, Zhao, Ying, Shukha, Yousef, Lu, Haocheng, Wang, Lu, Liu, Zhipeng, Liu, Cai, Zhao, Yang, Wang, Huilun, Zhao, Guizhen, Liang, Wenying, Fan, Yanbo, Chang, Lin, Yurdagul, Arif, Pattillo, Christopher B., Orr, A. Wayne, Aviram, Michael, Wen, Bo, Garcia-Barrio, Minerva T., Zhang, Jifeng, Liu, Wanqing, Sun, Duxin, Hayek, Tony, Chen, Y. Eugene, Rom, Oren
Published in Cell reports (Cambridge) (27.07.2021)
Published in Cell reports (Cambridge) (27.07.2021)
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Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
Zhao, Yang, Liu, Yuhao, Zhao, Guizhen, Lu, Haocheng, Liu, Yaozhong, Xue, Chao, Chang, Ziyi, Liu, Hongyu, Deng, Yongjie, Liang, Wenying, Wang, Huilun, Rom, Oren, Garcia-Barrio, Minerva T., Zhu, Tianqing, Guo, Yanhong, Chang, Lin, Lin, Jiandie, Chen, Y. Eugene, Zhang, Jifeng
Published in Cell reports (Cambridge) (31.10.2023)
Published in Cell reports (Cambridge) (31.10.2023)
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Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy
Zhao, Yang, Chang, Ziyi, Zhao, Guizhen, Lu, Haocheng, Xiong, Wenhao, Liang, Wenying, Wang, Huilun, Villacorta, Luis, Garcia-Barrio, Minerva T., Zhu, Tianqing, Guo, Yanhong, Fan, Yanbo, Chang, Lin, Schopfer, Francisco J., Freeman, Bruce A., Zhang, Jifeng, Chen, Y. Eugene
Published in Cardiovascular drugs and therapy (01.10.2021)
Published in Cardiovascular drugs and therapy (01.10.2021)
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Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation
Luo, Yonghong, Guo, Yanhong, Wang, Huilun, Yu, Minzhi, Hong, Kristen, Li, Dan, Li, Ruiting, Wen, Bo, Hu, Die, Chang, Lin, Zhang, Jifeng, Yang, Bo, Sun, Duxin, Schwendeman, Anna S., Eugene Chen, Y.
Published in EBioMedicine (01.12.2021)
Published in EBioMedicine (01.12.2021)
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KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction
Zhao, Guizhen, Chang, Ziyi, Zhao, Yang, Guo, Yanhong, Lu, Haocheng, Liang, Wenying, Rom, Oren, Wang, Huilun, Sun, Jinjian, Zhu, Tianqing, Fan, Yanbo, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T, Chen, Y Eugene, Zhang, Jifeng
Published in JCI insight (08.03.2021)
Published in JCI insight (08.03.2021)
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SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex
Lin, Liangguang Leo, Wang, Huilun Helen, Pederson, Brent, Wei, Xiaoqiong, Torres, Mauricio, Lu, You, Li, Zexin Jason, Liu, Xiaodan, Mao, Hancheng, Wang, Hui, Zhou, Linyao Elina, Zhao, Zhen, Sun, Shengyi, Qi, Ling
Published in Nature communications (16.02.2024)
Published in Nature communications (16.02.2024)
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Publisher Correction: SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex
Lin, Liangguang Leo, Wang, Huilun Helen, Pederson, Brent, Wei, Xiaoqiong, Torres, Mauricio, Lu, You, Li, Zexin Jason, Liu, Xiaodan, Mao, Hancheng, Wang, Hui, Zhou, Linyao Elina, Zhao, Zhen, Sun, Shengyi, Qi, Ling
Published in Nature communications (15.04.2024)
Published in Nature communications (15.04.2024)
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The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes
Wu, Shuangcheng Alivia, Shen, Chenchen, Wei, Xiaoqiong, Zhang, Xiawei, Wang, Siwen, Chen, Xinxin, Torres, Mauricio, Lu, You, Lin, Liangguang Leo, Wang, Huilun Helen, Hunter, Allen H., Fang, Deyu, Sun, Shengyi, Ivanova, Magdalena I., Lin, Yi, Qi, Ling
Published in Nature communications (30.05.2023)
Published in Nature communications (30.05.2023)
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New Insight Into Metformin-Induced Cholesterol-Lowering Effect Crosstalk Between Glucose and Cholesterol Homeostasis via ChREBP (Carbohydrate-Responsive Element-Binding Protein)-Mediated PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Regulation
Hu, Die, Guo, Yanhong, Wu, Renrong, Shao, Tiannan, Long, Junke, Yu, Bilian, Wang, Huilun, Luo, Yonghong, Lu, Haocheng, Zhang, Jifeng, Chen, Y Eugene, Peng, Daoquan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2021)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2021)
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Abstract 584: Myeloid Kruppel-like Factor 14 Mediates Sexual Dimorphism Of Abdominal Aortic Aneurysm Via Estrogen Receptor β
Wang, Huilun, Zhao, Guizhen, Chang, Lin, Zhang, Jifeng, Guo, Yanhong, Chen, Y. Eugene
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2023)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2023)
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Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport
Yuan, Wenmin, Yu, Bilian, Yu, Minzhi, Kuai, Rui, Morin, Emily E., Wang, Huilun, Hu, Die, Zhang, Jifeng, Moon, James J., Chen, Y. Eugene, Guo, Yanhong, Schwendeman, Anna
Published in Journal of controlled release (10.01.2021)
Published in Journal of controlled release (10.01.2021)
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KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression
Liang, Wenying, Lu, Haocheng, Sun, Jinjian, Zhao, Guizhen, Wang, Huilun, Guo, Yanhong, Eitzman, Daniel, Chen, Y Eugene, Fan, Yanbo, Zhang, Jifeng
Published in Thrombosis and haemostasis (01.05.2022)
Published in Thrombosis and haemostasis (01.05.2022)
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BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation
Chang, Ziyi, Zhao, Guizhen, Zhao, Yang, Lu, Haocheng, Xiong, Wenhao, Liang, Wenying, Sun, Jinjian, Wang, Huilun, Zhu, Tianqing, Rom, Oren, Guo, Yanhong, Fan, Yanbo, Chang, Lin, Yang, Bo, Garcia-Barrio, Minerva T, Lin, Jiandie D, Chen, Y Eugene, Zhang, Jifeng
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2020)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2020)
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Krüppel-like factor 14 deletion in myeloid cells accelerates atherosclerotic lesion development
Wang, Huilun, Guo, Yanhong, Lu, Haocheng, Luo, Yonghong, Hu, Wenting, Liang, Wenying, Garcia-Barrio, Minerva T, Chang, Lin, Schwendeman, Anna, Zhang, Jifeng, Chen, Y Eugene
Published in Cardiovascular research (29.01.2022)
Published in Cardiovascular research (29.01.2022)
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Krüppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-κB signaling pathway
Hu, Wenting, Lu, Haocheng, Zhang, Jifeng, Fan, Yanbo, Chang, Ziyi, Liang, Wenying, Wang, Huilun, Zhu, Tianqing, Garcia-Barrio, Minerva T., Peng, Daoquan, Chen, Y. Eugene, Guo, Yanhong
Published in Atherosclerosis (01.11.2018)
Published in Atherosclerosis (01.11.2018)
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