Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity
Li, Xin-Yang, Zhang, Ting-Jian, Kamara, Mohamed Olounfeh, Lu, Guo-Qing, Xu, Hai-Li, Wang, De-Pu, Meng, Fan-Hao
Published in Cell death & disease (11.07.2019)
Published in Cell death & disease (11.07.2019)
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Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC
Li, Xin-yang, Wang, De-pu, Lu, Guo-qing, Liu, Kai-li, Zhang, Ting-jian, Li, Shuai, Mohamed O, Kamara, Xue, Wen-han, Qian, Xin-hua, Meng, Fan-hao
Published in Journal of advanced research (01.11.2020)
Published in Journal of advanced research (01.11.2020)
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Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold
Wang, De-pu, Liu, Kai-li, Li, Xin-yang, Lu, Guo-qing, Xue, Wen-han, Qian, Xin-hua, Mohamed O, Kamara, Meng, Fan-hao
Published in European journal of medicinal chemistry (05.02.2021)
Published in European journal of medicinal chemistry (05.02.2021)
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Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation
Liu, Kai-li, Li, Xin-yang, Wang, De-pu, Xue, Wen-han, Qian, Xin-hua, Li, Yu-heng, Lin, Qi-qi, Li, Shuai, Meng, Fan-hao
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Novel 4,5-dihydrospiro[benzo[c]azepine-1,1′-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation
Li, Shuai, Li, Xin-yang, Zhang, Ting-jian, Zhu, Ju, Liu, Kai-li, Wang, De-pu, Meng, Fan-hao
Published in Bioorganic chemistry (01.06.2021)
Published in Bioorganic chemistry (01.06.2021)
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Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis
Li, Xin-yang, Wang, De-pu, Li, Shuai, Xue, Wen-han, Qian, Xin-hua, Liu, Kai-li, Li, Yu-heng, Lin, Qi-qi, Dong, Gang, Meng, Fan-hao, Jian, Ling-yan
Published in Bioorganic chemistry (01.02.2022)
Published in Bioorganic chemistry (01.02.2022)
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Design, synthesis and biological evaluation of novel (E)-N-phenyl-4-(pyridine-acylhydrazone) benzamide derivatives as potential antitumor agents for the treatment of multiple myeloma (MM)
Li, Xin-yang, Li, Shuai, Lu, Guo-qing, Wang, De-pu, Liu, Kai-li, Qian, Xin-hua, Xue, Wen-han, Meng, Fan-hao
Published in Bioorganic chemistry (01.10.2020)
Published in Bioorganic chemistry (01.10.2020)
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Magnetic field changes associated with three successive M-class solar flares on 2002 July 26
Wang, Pu, Ding, Ming-De, Ji, Hai-Sheng, Wang, Hai-Min
Published in Research in astronomy and astrophysics (01.06.2011)
Published in Research in astronomy and astrophysics (01.06.2011)
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