Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects
Wang, Chelsia Qiuxia, Krishnan, Vaidehi, Tay, Lavina Sierra, Chin, Desmond Wai Loon, Koh, Cai Ping, Chooi, Jing Yuan, Nah, Giselle Sek Suan, Du, Linsen, Jacob, Bindya, Yamashita, Namiko, Lai, Soak Kuan, Tan, Tuan Zea, Mori, Seiichi, Tanuichi, Ichiro, Tergaonkar, Vinay, Ito, Yoshiaki, Osato, Motomi
Published in Cell reports (Cambridge) (07.08.2014)
Published in Cell reports (Cambridge) (07.08.2014)
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Journal Article
Gamma/delta T cells as cellular vehicles for anti-tumor immunity
Wang, Chelsia Qiuxia, Lim, Pei Yu, Tan, Andy Hee-Meng
Published in Frontiers in immunology (11.01.2024)
Published in Frontiers in immunology (11.01.2024)
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Journal Article
Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia
Matsumura, Takayoshi, Nakamura-Ishizu, Ayako, Muddineni, Siva Sai Naga Anurag, Tan, Darren Qiancheng, Wang, Chelsia Qiuxia, Tokunaga, Kenji, Tirado-Magallanes, Roberto, Sian, Stephanie, Benoukraf, Touati, Okuda, Tsukasa, Asou, Norio, Matsuoka, Masao, Osato, Motomi, Suda, Toshio
Published in Blood (22.10.2020)
Published in Blood (22.10.2020)
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Journal Article
Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
Khattar, Ekta, Maung, Kyaw Ze Ya, Chew, Chen Li, Ghosh, Arkasubhra, Mok, Michelle Meng Huang, Lee, Pei, Zhang, Jun, Chor, Wei Hong Jeff, Cildir, Gökhan, Wang, Chelsia Qiuxia, Mohd-Ismail, Nur Khairiah, Chin, Desmond Wai Loon, Lee, Soo Chin, Yang, Henry, Shin, Yong-Jae, Nam, Do-Hyun, Chen, Liming, Kumar, Alan Prem, Deng, Lih Wen, Ikawa, Masahito, Gunaratne, Jayantha, Osato, Motomi, Tergaonkar, Vinay
Published in Nature communications (13.12.2019)
Published in Nature communications (13.12.2019)
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Journal Article
Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance
Numata, Akihiko, Kwok, Hui Si, Zhou, Qi-Ling, Li, Jia, Tirado-Magallanes, Roberto, Angarica, Vladimir Espinosa, Hannah, Rebecca, Park, Jihye, Wang, Chelsia Qiuxia, Krishnan, Vaidehi, Rajagopalan, Deepa, Zhang, Yanzhou, Zhou, Siqin, Welner, Robert S., Osato, Motomi, Jha, Sudhakar, Bohlander, Stefan K., Göttgens, Berthold, Yang, Henry, Benoukraf, Touati, Lough, John W., Bararia, Deepak, Tenen, Daniel G.
Published in Blood (08.10.2020)
Published in Blood (08.10.2020)
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Journal Article
Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells
Koh, Cai Ping, Bahirvani, Avinash Govind, Wang, Chelsia Qiuxia, Yokomizo, Tomomasa, Ng, Cherry Ee Lin, Du, Linsen, Tergaonkar, Vinay, Voon, Dominic Chih-Cheng, Kitamura, Hiroaki, Hosoi, Hiroki, Sonoki, Takashi, Michelle, Mok Meng Huang, Tan, Lii Jye, Niibori-Nambu, Akiko, Zhang, Yi, Perkins, Archibald S., Hossain, Zakir, Tenen, Daniel G., Ito, Yoshiaki, Venkatesh, Byrappa, Osato, Motomi
Published in Gene (30.01.2023)
Published in Gene (30.01.2023)
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Journal Article
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
Jacob, Bindya, Osato, Motomi, Yamashita, Namiko, Wang, Chelsia Qiuxia, Taniuchi, Ichiro, Littman, Dan R., Asou, Norio, Ito, Yoshiaki
Published in Blood (25.02.2010)
Published in Blood (25.02.2010)
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Journal Article
Runx3 deficiency results in myeloproliferative disorder in aged mice
Wang, Chelsia Qiuxia, Motoda, Lena, Satake, Masanobu, Ito, Yoshiaki, Taniuchi, Ichiro, Tergaonkar, Vinay, Osato, Motomi
Published in Blood (25.07.2013)
Published in Blood (25.07.2013)
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Journal Article
An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses
Wang, Chelsia Qiuxia, Choy, Fong Chan, Sanny, Arleen, Murakami, Takashi, Tan, Andy Hee-Meng, Lam, Kong-Peng
Published in Cells (Basel, Switzerland) (13.01.2023)
Published in Cells (Basel, Switzerland) (13.01.2023)
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Journal Article
Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress
Jayapal, Senthil Raja, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J, Lim, Shuhui, Tergaonkar, Vinay, Osato, Motomi, Kaldis, Philipp
Published in Haematologica (Roma) (01.04.2015)
Published in Haematologica (Roma) (01.04.2015)
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Journal Article
Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia
Niibori-Nambu, Akiko, Wang, Chelsia Qiuxia, Chin, Desmond Wai Loon, Chooi, Jing Yuan, Hosoi, Hiroki, Sonoki, Takashi, Tham, Cheng-Yong, Nah, Giselle Sek Suan, Cirovic, Branko, Tan, Darren Qiancheng, Takizawa, Hitoshi, Sashida, Goro, Goh, Yufen, Tng, Jiaqi, Fam, Wee Nih, Fullwood, Melissa Jane, Suda, Toshio, Yang, Henry, Tergaonkar, Vinay, Taniuchi, Ichiro, Li, Shang, Chng, Wee Joo, Osato, Motomi
Published in Gene (30.11.2024)
Published in Gene (30.11.2024)
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Journal Article
Runx Family Genes in Tissue Stem Cell Dynamics
Wang, Chelsia Qiuxia, Mok, Michelle Meng Huang, Yokomizo, Tomomasa, Tergaonkar, Vinay, Osato, Motomi
Published in Advances in experimental medicine and biology (2017)
Published in Advances in experimental medicine and biology (2017)
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Book Chapter
Journal Article
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia
Ong, Kelly Ooi Kee, Mok, Michelle Meng Huang, Niibori-Nambu, Akiko, Du, Linsen, Yanagida, Masatoshi, Wang, Chelsia Qiuxia, Bahirvani, Avinash Govind, Chin, Desmond Wai Loon, Koh, Cai Ping, Ng, King Pan, Yamashita, Namiko, Jacob, Bindya, Yokomizo, Tomomasa, Takizawa, Hitoshi, Matsumura, Takayoshi, Suda, Toshio, Lau, Jie-ying Amelia, Tan, Tuan Zea, Mori, Seiichi, Yang, Henry, Iwasaki, Masayuki, Minami, Takashi, Asou, Norio, Sun, Qiao-Yang, Ding, Ling-Wen, Koeffler, H. Phillip, Tenen, Daniel G., Shimizu, Ritsuko, Yamamoto, Masayuki, Ito, Yoshiaki, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh, Chng, Wee Joo, Osato, Motomi
Published in Experimental hematology (01.09.2024)
Published in Experimental hematology (01.09.2024)
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Journal Article
RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner
Abdallah, Mohamed Gaber, Niibori-Nambu, Akiko, Morii, Mariko, Yokomizo, Takako, Yokomizo, Tomomasa, Ideue, Takako, Kubota, Sho, Teoh, Vania Swee Imm, Mok, Michelle Meng Huang, Wang, Chelsia Qiuxia, Omar, Abdellah Ali, Tokunaga, Kenji, Iwanaga, Eisaku, Matsuoka, Masao, Asou, Norio, Nakagata, Naomi, Araki, Kimi, AboElenin, Mabrouk, Madboly, Sayed Hamada, Sashida, Goro, Osato, Motomi
Published in Leukemia (01.10.2021)
Published in Leukemia (01.10.2021)
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Journal Article
Aberrant activation of the GIMAP enhancer by oncogenic transcription factors in T-cell acute lymphoblastic leukemia
Liau, W S, Tan, S H, Ngoc, P C T, Wang, C Q, Tergaonkar, V, Feng, H, Gong, Z, Osato, M, Look, A T, Sanda, T
Published in Leukemia (01.08.2017)
Published in Leukemia (01.08.2017)
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Journal Article
Cyclin A2 regulates erythrocyte morphology and numbers
Jayapal, Senthil Raja, Ang, Heather Yin-Kuan, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J, Xuan, Gan Xiao, Yu, Weimiao, Tergaonkar, Vinay, Osato, Motomi, Lim, Bing, Kaldis, Philipp
Published in Cell cycle (Georgetown, Tex.) (16.11.2016)
Published in Cell cycle (Georgetown, Tex.) (16.11.2016)
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Journal Article
Runx family genes, niche, and stem cell quiescence
Wang, Chelsia Qiuxia, Jacob, Bindya, Nah, Giselle Sek Suan, Osato, Motomi
Published in Blood cells, molecules, & diseases (15.04.2010)
Published in Blood cells, molecules, & diseases (15.04.2010)
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Journal Article
RUNX1 point mutations potentially identify a subset of early immature T-cell acute lymphoblastic leukaemia that may originate from differentiated T-cells
Mok, Michelle Meng Huang, Du, Linsen, Wang, Chelsia Qiuxia, Tergaonkar, Vinay, Liu, Te Chih, Yin Kham, Shirley Kow, Sanda, Takaomi, Yeoh, Allen Eng-Juh, Osato, Motomi
Published in Gene (15.07.2014)
Published in Gene (15.07.2014)
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Journal Article
Hematopoietic stem cell enhancer: a powerful tool in stem cell biology
Koh, Cai Ping, Ng, Cherry Ee Lin, Nah, Giselle Sek Suan, Wang, Chelsia Qiuxia, Tergaonkar, Vinay, Matsumura, Takayoshi, Yokomizo, Tomomasa, Suda, Toshio, Osato, Motomi
Published in Histology and histopathology (01.06.2015)
Published in Histology and histopathology (01.06.2015)
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Journal Article