Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
Sulahian, Rita, Kwon, Jason J., Walsh, Katherine H., Pailler, Emma, Bosse, Timothy L., Thaker, Maneesha, Almanza, Diego, Dempster, Joshua M., Pan, Joshua, Piccioni, Federica, Dumont, Nancy, Gonzalez, Alfredo, Rennhack, Jonathan, Nabet, Behnam, Bachman, John A., Goodale, Amy, Lee, Yenarae, Bagul, Mukta, Liao, Rosy, Navarro, Adrija, Yuan, Tina L., Ng, Raymond W.S., Raghavan, Srivatsan, Gray, Nathanael S., Tsherniak, Aviad, Vazquez, Francisca, Root, David E., Firestone, Ari J., Settleman, Jeff, Hahn, William C., Aguirre, Andrew J.
Published in Cell reports (Cambridge) (01.10.2019)
Published in Cell reports (Cambridge) (01.10.2019)
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MDM2 and MDM4 Are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors
Howard, Thomas P, Arnoff, Taylor E, Song, Melinda R, Giacomelli, Andrew O, Wang, Xiaofeng, Hong, Andrew L, Dharia, Neekesh V, Wang, Su, Vazquez, Francisca, Pham, Minh-Tam, Morgan, Ann M, Wachter, Franziska, Bird, Gregory H, Kugener, Guillaume, Oberlick, Elaine M, Rees, Matthew G, Tiv, Hong L, Hwang, Justin H, Walsh, Katherine H, Cook, April, Krill-Burger, John M, Tsherniak, Aviad, Gokhale, Prafulla C, Park, Peter J, Stegmaier, Kimberly, Walensky, Loren D, Hahn, William C, Roberts, Charles W M
Published in Cancer research (Chicago, Ill.) (01.05.2019)
Published in Cancer research (Chicago, Ill.) (01.05.2019)
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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
Waters, Andrew M., Khatib, Tala O., Papke, Bjoern, Goodwin, Craig M., Hobbs, G. Aaron, Diehl, J. Nathaniel, Yang, Runying, Edwards, A. Cole, Walsh, Katherine H., Sulahian, Rita, McFarland, James M., Kapner, Kevin S., Gilbert, Thomas S.K., Stalnecker, Clint A., Javaid, Sehrish, Barkovskaya, Anna, Grover, Kajal R., Hibshman, Priya S., Blake, Devon R., Schaefer, Antje, Nowak, Katherine M., Klomp, Jennifer E., Hayes, Tikvah K., Kassner, Michelle, Tang, Nanyun, Tanaseichuk, Olga, Chen, Kaisheng, Zhou, Yingyao, Kalkat, Manpreet, Herring, Laura E., Graves, Lee M., Penn, Linda Z., Yin, Hongwei H., Aguirre, Andrew J., Hahn, William C., Cox, Adrienne D., Der, Channing J.
Published in Cell reports (Cambridge) (29.06.2021)
Published in Cell reports (Cambridge) (29.06.2021)
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Abstract 4550: Increased IL-27 is associated with poor prognosis in renal cell carcinoma and supports use of SRF388, a first-in-class IL-27p28 blocking antibody, to counteract IL-27-mediated immunosuppression in this setting
Rausch, Matthew, Hua, Jing, Moodley, Devapregasan, White, Kerry F., Walsh, Katherine H., Miller, Christine E., Tan, Gege, Lee, Benjamin H., Cousineau, Isabelle, Lattouf, Jean-Baptiste, Stagg, John, Palombella, Vito J., Holland, Pamela M., Hill, Jonathan A.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 558: MERTK-specific antibodies that have therapeutic antitumor activity in mice disrupt the integrity of the retinal pigmented epithelium in cynomolgus monkeys
White, Kerry F., Rausch, Matthew, Hua, Jing, Walsh, Katherine H., Miller, Christine E., Wells, Christopher C., Moodley, Devapregasan, Lee, Benjamin H., Chappel, Scott C., Holland, Pamela M., Hill, Jonathan A.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2867: MDM2 and MDM4 are therapeutic vulnerabilities in malignant rhabdoid tumors
Howard, Thomas P., Arnoff, Taylor E., Song, Melinda R., Giacomelli, Andrew O., Wang, Xiaofeng, Hong, Andrew L., Dharia, Neekesh V., Wang, Su, Vazquez, Francisca, Pham, Minh-Tam, Morgan, Ann M., Wachter, Franziska, Bird, Gregory H., Kugener, Guillaume, Oberlick, Elaine M., Rees, Matthew G., Tiv, Hong, Hwang, Justin H., Walsh, Katherine H., Cook, April, Krill-Burger, John M., Tsherniak, Aviad, Gokhale, Prafulla C., Park, Peter J., Stegmaier, Kimberly, Walensky, Loren D., Hahn, William C., Roberts, Charles W.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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