An optimized bioluminescent substrate for non-invasive imaging in the brain
Su, Yichi, Walker, Joel R., Hall, Mary P., Klein, Mark A., Wu, Xiang, Encell, Lance P., Casey, Kerriann M., Liu, Lan Xiang, Hong, Guosong, Lin, Michael Z., Kirkland, Thomas A.
Published in Nature chemical biology (01.06.2023)
Published in Nature chemical biology (01.06.2023)
Get full text
Journal Article
Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice
Gaspar, Natasa, Walker, Joel R., Zambito, Giorgia, Marella-Panth, Kranthi, Lowik, Clemens, Kirkland, Thomas A., Mezzanotte, Laura
Published in Journal of photochemistry and photobiology. B, Biology (01.03.2021)
Published in Journal of photochemistry and photobiology. B, Biology (01.03.2021)
Get full text
Journal Article
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
Grohmann, Christoph, Magtoto, Charlene M., Walker, Joel R., Chua, Ngee Kiat, Gabrielyan, Anna, Hall, Mary, Cobbold, Simon A., Mieruszynski, Stephen, Brzozowski, Martin, Simpson, Daniel S., Dong, Hao, Dorizzi, Bridget, Jacobsen, Annette V., Morrish, Emma, Silke, Natasha, Murphy, James M., Heath, Joan K., Testa, Andrea, Maniaci, Chiara, Ciulli, Alessio, Lessene, Guillaume, Silke, John, Feltham, Rebecca
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
Get full text
Journal Article
Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression
Carossino, Mariano, Kenney, Devin, O'Connell, Aoife K, Montanaro, Paige, Tseng, Anna E, Gertje, Hans P, Grosz, Kyle A, Ericsson, Maria, Huber, Bertrand R, Kurnick, Susanna A, Subramaniam, Saravanan, Kirkland, Thomas A, Walker, Joel R, Francis, Kevin P, Klose, Alexander D, Paragas, Neal, Bosmann, Markus, Saeed, Mohsan, Balasuriya, Udeni B R, Douam, Florian, Crossland, Nicholas A
Published in Viruses (05.03.2022)
Published in Viruses (05.03.2022)
Get full text
Journal Article
Optogenetic Control of Non‐Apoptotic Cell Death
He, Lian, Huang, Zixian, Huang, Kai, Chen, Rui, Nguyen, Nhung T., Wang, Rui, Cai, Xiaoli, Huang, Zhiquan, Siwko, Stefan, Walker, Joel R., Han, Gang, Zhou, Yubin, Jing, Ji
Published in Advanced science (01.07.2021)
Published in Advanced science (01.07.2021)
Get full text
Journal Article
NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform
Gaspar, Natasa, Zambito, Giorgia, Dautzenberg, Iris J C, Cramer, Steve J, Hoeben, Rob C, Lowik, Clemens, Walker, Joel R, Kirkland, Thomas A, Smith, Thomas P, van Weerden, Wytske M, de Vrij, Jeroen, Mezzanotte, Laura
Published in International journal of molecular sciences (15.08.2020)
Published in International journal of molecular sciences (15.08.2020)
Get full text
Journal Article
Optimized in vivo multispectral bioluminescent imaging of tumor biology using engineered BRET reporters
Labra, Bryan, Parag-Sharma, Kshitij, Powers, John J., Srivastava, Sonal, Walker, Joel R., Kirkland, Thomas A., Brennan, Caroline K., Prescher, Jennifer A., Amelio, Antonio L.
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
Get full text
Journal Article
In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein
Perez, Gloria I., Broadbent, David, Zarea, Ahmed A., Dolgikh, Benedikt, Bernard, Matthew P., Withrow, Alicia, McGill, Amelia, Toomajian, Victoria, Thampy, Lukose K., Harkema, Jack, Walker, Joel R., Kirkland, Thomas A., Bachmann, Michael H., Schmidt, Jens, Kanada, Masamitsu
Published in Genetics & genomics next (01.03.2022)
Published in Genetics & genomics next (01.03.2022)
Get full text
Journal Article
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Su, Yichi, Walker, Joel R., Park, Yunhee, Smith, Thomas P., Liu, Lan Xiang, Hall, Mary P., Labanieh, Louai, Hurst, Robin, Wang, David C., Encell, Lance P., Kim, Namdoo, Zhang, Feijie, Kay, Mark A., Casey, Kerriann M., Majzner, Robbie G., Cochran, Jennifer R., Mackall, Crystal L., Kirkland, Thomas A., Lin, Michael Z.
Published in Nature methods (01.08.2020)
Published in Nature methods (01.08.2020)
Get full text
Journal Article
Identification of NanoLuciferase Substrates Transported by Human ABCB1 and ABCG2 and their Zebrafish Homologs at the Blood-Brain Barrier
Quinlan, John A, Sabbineni, Sashank, Robey, Robert W, Lipsey, Crystal C, Inglut, Collin T, Thomas, Joanna R, Walker, Joel R, Zhou, Wenhui, Huang, Huang-Chiao, Gottesman, Michael M
Published in Molecular pharmacology (25.09.2024)
Published in Molecular pharmacology (25.09.2024)
Get full text
Journal Article
Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders
Gurney, Mark E, Nugent, Richard A, Mo, Xuesheng, Sindac, Janice A, Hagen, Timothy J, Fox, David, O’Donnell, James M, Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Groppi, Vincent E, Bailie, Marc, White, Ronald E, Romero, Donna L, Vellekoop, A. Samuel, Walker, Joel R, Surman, Matthew D, Zhu, Lei, Campbell, Robert F
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
Get full text
Journal Article
Coelenterazine analogues emit red-shifted bioluminescence with NanoLuc
Shakhmin, Anton, Hall, Mary P, Machleidt, Thomas, Walker, Joel R, Wood, Keith V, Kirkland, Thomas A
Published in Organic & biomolecular chemistry (18.10.2017)
Published in Organic & biomolecular chemistry (18.10.2017)
Get full text
Journal Article
Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide
Walker, Joel R., Alshafie, Galal, Nieves, Nirca, Ahrens, Jamie, Clagett-Dame, Margaret, Abou-Issa, Hussein, Curley, Robert W.
Published in Bioorganic & medicinal chemistry (01.05.2006)
Published in Bioorganic & medicinal chemistry (01.05.2006)
Get full text
Journal Article
Three Efficient Methods for Preparation of Coelenterazine Analogues
Shakhmin, Anton, Hall, Mary P., Walker, Joel R., Machleidt, Thomas, Binkowski, Brock F., Wood, Keith V., Kirkland, Thomas A.
Published in Chemistry : a European journal (18.07.2016)
Published in Chemistry : a European journal (18.07.2016)
Get full text
Journal Article
Synthesis of isoindolinones via inverse-electron demand Diels–Alder cycloadditions
Huntley, Raymond J., Gurram, Mahender, Walker, Joel R., Jenkins, David M., Robé, Emmanuel J., Ahmed, Feryan
Published in Tetrahedron letters (02.04.2014)
Published in Tetrahedron letters (02.04.2014)
Get full text
Journal Article
Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors
Walker, Joel R, Hall, Mary P, Zimprich, Chad A, Robers, Matthew B, Duellman, Sarah J, Machleidt, Thomas, Rodriguez, Jacquelynn, Zhou, Wenhui
Published in ACS chemical biology (21.04.2017)
Published in ACS chemical biology (21.04.2017)
Get full text
Journal Article
Inhibition of Mammary Tumor Growth by a Novel Nontoxic Retinoid: Chemotherapeutic Evaluation of a C-Linked Analog of 4-HPR-Glucuronide
ALSHAFIE, Galal A, WALKER, Joel R, CURLEY, Robert W, CLAGETT-DAME, Margaret, HIGHLAND, Margaret A, NIEVES, Nirca J, STONEROCK, Laura A, ABOU-ISSA, Hussein
Published in Anticancer research (01.05.2005)
Get full text
Published in Anticancer research (01.05.2005)
Journal Article