Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose
Ferrara, Claudia, Grau, Sandra, Jäger, Christiane, Sondermann, Peter, Brünker, Peter, Waldhauer, Inja, Hennig, Michael, Ruf, Armin, Rufer, Arne Christian, Stihle, Martine, Umaña, Pablo, Benz, Jörg
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2011)
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Journal Article
Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction
Steinle, Alexander, Welte, Stefan, Kuttruff, Sabrina, Waldhauer, Inja
Published in Nature Immunology (01.12.2006)
Published in Nature Immunology (01.12.2006)
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Journal Article
Tumor-associated MICA is shed by ADAM proteases
Waldhauer, Inja, Goehlsdorf, Dennis, Gieseke, Friederike, Weinschenk, Toni, Wittenbrink, Mareike, Ludwig, Andreas, Stevanovic, Stefan, Rammensee, Hans-Georg, Steinle, Alexander
Published in Cancer research (Chicago, Ill.) (01.08.2008)
Published in Cancer research (Chicago, Ill.) (01.08.2008)
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Journal Article
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy
Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J, Gerrits, Danny, Geven, Edwin J W, Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J Mark, Garg, Pradeep K, Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C, Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis
Brünker, Peter, Wartha, Katharina, Friess, Thomas, Grau-Richards, Sandra, Waldhauer, Inja, Koller, Claudia Ferrara, Weiser, Barbara, Majety, Meher, Runza, Valeria, Niu, Huifeng, Packman, Kathryn, Feng, Ningping, Daouti, Sherif, Hosse, Ralf J, Mössner, Ekkehard, Weber, Thomas G, Herting, Frank, Scheuer, Werner, Sade, Hadassah, Shao, Cuiying, Liu, Bin, Wang, Peng, Xu, Gary, Vega-Harring, Suzana, Klein, Christian, Bosslet, Klaus, Umaña, Pablo
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure
Spreafico, Anna, Couselo, Eva Muñoz, Irmisch, Anja, Bessa, Juliana, Au-Yeung, George, Bechter, Oliver, Svane, Inge Marie, Sanmamed, Miguel F, Gambardella, Valentina, McKean, Meredith, Callahan, Margaret, Dummer, Reinhard, Klein, Christian, Umaña, Pablo, Justies, Nicole, Heil, Florian, Fahrni, Linda, Opolka-Hoffmann, Eugenia, Waldhauer, Inja, Bleul, Conrad, Staack, Roland F, Karanikas, Vaios, Fowler, Stephen
Published in Frontiers in oncology (21.03.2024)
Published in Frontiers in oncology (21.03.2024)
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Journal Article
Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration
Van De Vyver, Arthur J., Walz, Antje-Christine, Heins, Mariette S., Abdolzade-Bavil, Afsaneh, Kraft, Thomas E., Waldhauer, Inja, Otteneder, Michael B.
Published in Frontiers in pharmacology (29.08.2022)
Published in Frontiers in pharmacology (29.08.2022)
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Journal Article
Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines
Klein, Christian, Waldhauer, Inja, Nicolini, Valeria G., Freimoser-Grundschober, Anne, Nayak, Tapan, Vugts, Danielle J., Dunn, Claire, Bolijn, Marije, Benz, Jörg, Stihle, Martine, Lang, Sabine, Roemmele, Michaele, Hofer, Thomas, van Puijenbroek, Erwin, Wittig, David, Moser, Samuel, Ast, Oliver, Brünker, Peter, Gorr, Ingo H., Neumann, Sebastian, de Vera Mudry, Maria Cristina, Hinton, Heather, Crameri, Flavio, Saro, Jose, Evers, Stefan, Gerdes, Christian, Bacac, Marina, van Dongen, Guus, Moessner, Ekkehard, Umaña, Pablo
Published in Oncoimmunology (04.03.2017)
Published in Oncoimmunology (04.03.2017)
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Journal Article
Novel Tumor-Targeted, Engineered IL-2 Variant (IL2v)-Based Immunocytokines For Immunotherapy Of Cancer
Klein, Christian, Waldhauer, Inja, Nicolini, Valeria, Dunn, Claire, Freimoser-Grundschober, Anne, Danny, Gerrits, Boerman, Otto, Nayak, Tapan, Herter, Sylvia, Van Puijenbroek, Erwin, Ast, Oliver, Hofer, Thomas, Hosse, Ralf, Lang, Sabine, Neumann, Sebastian, Kettenberger, Hubert, Neubauer, Markus, Gorr, Ingo, Tuerck, Dietrich, Evers, Stefan, Gerdes, Christian, Levitsky, Victor, Bacac, Marina, Moessner, Ekkehard, Umana, Pablo
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
Codarri Deak, Laura, Nicolini, Valeria, Hashimoto, Masao, Karagianni, Maria, Schwalie, Petra C., Lauener, Laura, Varypataki, Eleni Maria, Richard, Marine, Bommer, Esther, Sam, Johannes, Joller, Stefanie, Perro, Mario, Cremasco, Floriana, Kunz, Leo, Yanguez, Emilio, Hüsser, Tamara, Schlenker, Ramona, Mariani, Marisa, Tosevski, Vinko, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Colombetti, Sara, Gueripel, Xavier, Wullschleger, Stephan, Tichet, Melanie, Hanahan, Douglas, Kissick, Haydn T., Leclair, Stephane, Freimoser-Grundschober, Anne, Seeber, Stefan, Teichgräber, Volker, Ahmed, Rafi, Klein, Christian, Umaña, Pablo
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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Journal Article
Correction: Preclinical In Vivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 TâCell Bispecific in Combination with AntiâPDâL1
Sánchez, Javier, Nicolini, Valeria, Fahrni, Linda, Waldhauer, Inja, Walz, AntjeâChristine, Jamois, Candice, Fowler, Stephen
Published in The AAPS journal (01.05.2023)
Published in The AAPS journal (01.05.2023)
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Journal Article
A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents
Herter, Sylvia, Morra, Laura, Schlenker, Ramona, Sulcova, Jitka, Fahrni, Linda, Waldhauer, Inja, Lehmann, Steffi, Reisländer, Timo, Agarkova, Irina, Kelm, Jens M., Klein, Christian, Umana, Pablo, Bacac, Marina
Published in Cancer Immunology, Immunotherapy (01.01.2017)
Published in Cancer Immunology, Immunotherapy (01.01.2017)
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Journal Article
Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models
Herter, Sylvia, Herting, Frank, Mundigl, Olaf, Waldhauer, Inja, Weinzierl, Tina, Fauti, Tanja, Muth, Gunter, Ziegler-Landesberger, Doris, Van Puijenbroek, Erwin, Lang, Sabine, Duong, Minh Ngoc, Reslan, Lina, Gerdes, Christian A, Friess, Thomas, Baer, Ute, Burtscher, Helmut, Weidner, Michael, Dumontet, Charles, Umana, Pablo, Niederfellner, Gerhard, Bacac, Marina, Klein, Christian
Published in Molecular cancer therapeutics (01.10.2013)
Published in Molecular cancer therapeutics (01.10.2013)
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Journal Article
A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease
Peterson, Laurence B., Bell, Charles J.M., Howlett, Sarah K., Pekalski, Marcin L., Brady, Kevin, Hinton, Heather, Sauter, Denise, Todd, John A., Umana, Pablo, Ast, Oliver, Waldhauer, Inja, Freimoser-Grundschober, Anne, Moessner, Ekkehard, Klein, Christian, Hosse, Ralf J., Wicker, Linda S.
Published in Journal of autoimmunity (01.12.2018)
Published in Journal of autoimmunity (01.12.2018)
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Journal Article
Abstract 2774: The triple combination of the FAP-IL2v immunocytokine with PD-L1 checkpoint inhibitory and CD40 agonistic antibodies results in long-term tumor control in the orthotopic PancO2 model
Nicolini, Valeria, Waldhauer, Inja, Freimoser, Anne, Corse, Emily, Charo, Jahad, Umana, Pablo, Klein, Christian
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Preclinical InVivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T-Cell Bispecific in Combination with Anti-PD-L1
Sánchez, Javier, Nicolini, Valeria, Fahrni, Linda, Waldhauer, Inja, Walz, Antje-Christine, Jamois, Candice, Fowler, Stephen, Simon, Silke, Klein, Christian, Umaña, Pablo, Friberg, Lena E., Frances, Nicolas
Published in The AAPS journal (07.10.2022)
Published in The AAPS journal (07.10.2022)
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Journal Article
Correction: Preclinical In Vivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T‑Cell Bispecific in Combination with Anti‑PD‑L1
Sánchez, Javier, Nicolini, Valeria, Fahrni, Linda, Waldhauer, Inja, Walz, Antje‑Christine, Jamois, Candice, Fowler, Stephen, Simon, Silke, Klein, Christian, Umaña, Pablo, Friberg, Lena E., Frances, Nicolas
Published in The AAPS journal (01.04.2023)
Published in The AAPS journal (01.04.2023)
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Journal Article
Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis
Laverman, Peter, van der Geest, Tessa, Terry, Samantha Y A, Gerrits, Danny, Walgreen, Birgitte, Helsen, Monique M, Nayak, Tapan K, Freimoser-Grundschober, Anne, Waldhauer, Inja, Hosse, Ralf J, Moessner, Ekkehard, Umana, Pablo, Klein, Christian, Oyen, Wim J G, Koenders, Marije I, Boerman, Otto C
Published in Journal of Nuclear Medicine (01.05.2015)
Published in Journal of Nuclear Medicine (01.05.2015)
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TGF-β and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells
EISELE, Günter, WISCHHUSEN, Jörg, MITTELBRONN, Michel, MEYERMANN, Richard, WALDHAUER, Inja, STEINLE, Alexander, WELLER, Michael, FRIESE, Manuel A
Published in Brain (London, England : 1878) (01.09.2006)
Published in Brain (London, England : 1878) (01.09.2006)
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