NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
Romee, Rizwan, Foley, Bree, Lenvik, Todd, Wang, Yue, Zhang, Bin, Ankarlo, Dave, Luo, Xianghua, Cooley, Sarah, Verneris, Mike, Walcheck, Bruce, Miller, Jeffrey
Published in Blood (02.05.2013)
Published in Blood (02.05.2013)
Get full text
Journal Article
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy
Pomeroy, Emily J., Hunzeker, John T., Kluesner, Mitchell G., Lahr, Walker S., Smeester, Branden A., Crosby, Margaret R., Lonetree, Cara-lin, Yamamoto, Kenta, Bendzick, Laura, Miller, Jeffrey S., Geller, Melissa A., Walcheck, Bruce, Felices, Martin, Webber, Beau R., Starr, Timothy K., Moriarity, Branden S.
Published in Molecular therapy (08.01.2020)
Published in Molecular therapy (08.01.2020)
Get full text
Journal Article
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Cichocki, Frank, Bjordahl, Ryan, Goodridge, Jodie P., Mahmood, Sajid, Gaidarova, Svetlana, Abujarour, Ramzey, Davis, Zachary B., Merino, Aimee, Tuininga, Katie, Wang, Hongbo, Kumar, Akhilesh, Groff, Brian, Witty, Alec, Bonello, Greg, Huffman, Janel, Dailey, Thomas, Lee, Tom T., Malmberg, Karl-Johan, Walcheck, Bruce, Höpken, Uta, Rehm, Armin, Valamehr, Bahram, Miller, Jeffrey S.
Published in Nature communications (29.11.2022)
Published in Nature communications (29.11.2022)
Get full text
Journal Article
Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells
Jing, Yawu, Ni, Zhenya, Wu, Jianming, Higgins, LeeAnn, Markowski, Todd W, Kaufman, Dan S, Walcheck, Bruce
Published in PloS one (27.03.2015)
Published in PloS one (27.03.2015)
Get full text
Journal Article
Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17
Buchanan, Petra C., Boylan, Kristin L.M., Walcheck, Bruce, Heinze, Rachel, Geller, Melissa A., Argenta, Peter A., Skubitz, Amy P.N.
Published in The Journal of biological chemistry (14.04.2017)
Published in The Journal of biological chemistry (14.04.2017)
Get full text
Journal Article
Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation
Mishra, Hemant K, Dixon, Kate J, Pore, Nabendu, Felices, Martin, Miller, Jeffrey S, Walcheck, Bruce
Published in Frontiers in immunology (22.07.2021)
Published in Frontiers in immunology (22.07.2021)
Get full text
Journal Article
Blocking ADAM17 Function with a Monoclonal Antibody Improves Sepsis Survival in a Murine Model of Polymicrobial Sepsis
Mishra, Hemant K, Ma, Jing, Mendez, Daniel, Hullsiek, Robert, Pore, Nabendu, Walcheck, Bruce
Published in International journal of molecular sciences (12.09.2020)
Published in International journal of molecular sciences (12.09.2020)
Get full text
Journal Article
Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells
Snyder, Kristin M, Hullsiek, Robert, Mishra, Hemant K, Mendez, Daniel C, Li, Yunfang, Rogich, Allison, Kaufman, Dan S, Wu, Jianming, Walcheck, Bruce
Published in Frontiers in immunology (06.12.2018)
Published in Frontiers in immunology (06.12.2018)
Get full text
Journal Article
An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model
Hedges, Jodi F., Snyder, Deann T., Robison, Amanda, Grifka-Walk, Heather M., Blackwell, Karlin, Shepardson, Kelly, Kominsky, Douglas, Rynda-Apple, Agnieszka, Walcheck, Bruce, Jutila, Mark A.
Published in Frontiers in immunology (10.06.2022)
Published in Frontiers in immunology (10.06.2022)
Get full text
Journal Article
Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding
Wang, Yue, Herrera, Amy H, Li, Ying, Belani, Kiran K, Walcheck, Bruce
Published in The Journal of immunology (1950) (15.02.2009)
Published in The Journal of immunology (1950) (15.02.2009)
Get full text
Journal Article
iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma
Dixon, Kate J, Snyder, Kristin M, Khaw, Melissa, Hullsiek, Robert, Davis, Zachary B, Matson, Anders W, Shirinbak, Soheila, Hancock, Bryan, Bjordahl, Ryan, Hosking, Martin, Miller, Jeffrey S, Valamehr, Bahram, Wu, Jianming, Walcheck, Bruce
Published in Frontiers in immunology (19.07.2024)
Published in Frontiers in immunology (19.07.2024)
Get full text
Journal Article
Tumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes
Ku, Amy W, Muhitch, Jason B, Powers, Colin A, Diehl, Michael, Kim, Minhyung, Fisher, Daniel T, Sharda, Anand P, Clements, Virginia K, O'Loughlin, Kieran, Minderman, Hans, Messmer, Michelle N, Ma, Jing, Skitzki, Joseph J, Steeber, Douglas A, Walcheck, Bruce, Ostrand-Rosenberg, Suzanne, Abrams, Scott I, Evans, Sharon S
Published in eLife (08.12.2016)
Published in eLife (08.12.2016)
Get full text
Journal Article
Association between MICA polymorphisms, s-MICA levels, and pancreatic cancer risk in a population-based case-control study
Onyeaghala, Guillaume, Lane, John, Pankratz, Nathan, Nelson, Heather H, Thyagarajan, Bharat, Walcheck, Bruce, Anderson, Kristin E, Prizment, Anna E
Published in PloS one (05.06.2019)
Published in PloS one (05.06.2019)
Get full text
Journal Article
Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells
Hullsiek, Robert, Li, Yunfang, Snyder, Kristin M, Wang, Sam, Di, Da, Borgatti, Antonella, Lee, Chae, Moore, Peter F, Zhu, Cong, Fattori, Chiara, Modiano, Jaime F, Wu, Jianming, Walcheck, Bruce
Published in Frontiers in immunology (24.02.2022)
Published in Frontiers in immunology (24.02.2022)
Get full text
Journal Article
Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages
Bell, Jessica H., Herrera, Amy H., Li, Ying, Walcheck, Bruce
Published in Journal of leukocyte biology (01.07.2007)
Published in Journal of leukocyte biology (01.07.2007)
Get full text
Journal Article