Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics
Waight, Andrew B, Bargsten, Katja, Doronina, Svetlana, Steinmetz, Michel O, Sussman, Django, Prota, Andrea E
Published in PloS one (12.08.2016)
Published in PloS one (12.08.2016)
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Journal Article
Crystal structure of a eukaryotic phosphate transporter
Pedersen, Bjørn P, Kumar, Hemant, Waight, Andrew B, Risenmay, Aaron J, Roe-Zurz, Zygy, Chau, Bryant H, Schlessinger, Avner, Bonomi, Massimiliano, Harries, William, Sali, Andrej, Johri, Atul K, Stroud, Robert M
Published in Nature (London) (25.04.2013)
Published in Nature (London) (25.04.2013)
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Journal Article
Structural basis for alternating access of a eukaryotic calcium/proton exchanger
Waight, Andrew B, Pedersen, Bjørn Panyella, Schlessinger, Avner, Bonomi, Massimiliano, Chau, Bryant H, Roe-Zurz, Zygy, Risenmay, Aaron J, Sali, Andrej, Stroud, Robert M
Published in Nature (London) (04.07.2013)
Published in Nature (London) (04.07.2013)
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Journal Article
A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties
Waight, Andrew B., Prihoda, David, Shrestha, Rojan, Metcalf, Kevin, Bailly, Marc, Ancona, Marco, Widatalla, Talal, Rollins, Zachary, Cheng, Alan C, Bitton, Danny A., Fayadat-Dilman, Laurence
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Journal Article
Structure and mechanism of a pentameric formate channel
Waight, Andrew B, Wang, Da-Neng, Love, James
Published in Nature structural & molecular biology (01.01.2010)
Published in Nature structural & molecular biology (01.01.2010)
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Journal Article
Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates
Neumann, Christopher S, Olivas, Kathleen C, Anderson, Martha E, Cochran, Julia H, Jin, Steven, Li, Fu, Loftus, Luke V, Meyer, David W, Neale, Jason, Nix, Jay C, Pittman, Paul G, Simmons, Jessica K, Ulrich, Michelle L, Waight, Andrew B, Wong, Abbie, Zaval, Margo C, Zeng, Weiping, Lyon, Robert P, Senter, Peter D
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Journal Article
Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates
Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Setter, Jocelyn R, Hunter, Joshua H, Cochran, Julia H, Waight, Andrew B, Gordon, Kristine A, Toki, Brian E, Emmerton, Kim K, Zeng, Weiping, Stone, Ivan J, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Journal Article
A previously undescribed tubulin binder
Field, Jessica J., Waight, Andrew B., Senter, Peter D.
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
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Journal Article
Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR + and Heterogeneous Tumor Models
Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Lai, Holden W H, Leiske, Christopher I, Emmerton, Kim K, Waight, Andrew B, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
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Journal Article
Engineering an Enhanced EGFR Engager: Humanization of Cetuximab for Improved Developability
Goulet, Dennis R, Chatterjee, Soumili, Lee, Wai-Ping, Waight, Andrew B, Zhu, Yi, Mak, Amanda Nga-Sze
Published in Antibodies (Basel) (13.01.2022)
Published in Antibodies (Basel) (13.01.2022)
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Journal Article
Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation
Prota, Andrea E., Setter, Jocelyn, Waight, Andrew B., Bargsten, Katja, Murga, Juan, Diaz, José Fernando, Steinmetz, Michel O.
Published in Journal of molecular biology (31.07.2016)
Published in Journal of molecular biology (31.07.2016)
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Journal Article
Codon Optimization Using a Recurrent Neural Network
Goulet, Dennis R, Yan, Yongqi, Agrawal, Palak, Waight, Andrew B, Mak, Amanda Nga-Sze, Zhu, Yi
Published in Journal of computational biology (01.01.2023)
Published in Journal of computational biology (01.01.2023)
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Journal Article
ACE2-Fc fusion protein overcomes viral escape by potently neutralizing SARS-CoV-2 variants of concern
Tsai, Tsung-I, Khalili, Jahan S., Gilchrist, Mark, Waight, Andrew B., Cohen, Daniella, Zhuo, Shi, Zhang, Yong, Ding, Muran, Zhu, Hai, Mak, Amanda Nga-Sze, Zhu, Yi, Goulet, Dennis R.
Published in Antiviral research (01.03.2022)
Published in Antiviral research (01.03.2022)
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Journal Article
Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models
Moquist, Philip N, Bovee, Tim D, Waight, Andrew B, Mitchell, Jamie A, Miyamoto, Jamie B, Mason, Marsha L, Emmerton, Kim K, Stevens, Nicole, Balasubramanian, Cindy, Simmons, Jessica K, Lyon, Robert P, Senter, Peter D, Doronina, Svetlana O
Published in Molecular cancer therapeutics (01.02.2021)
Published in Molecular cancer therapeutics (01.02.2021)
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Journal Article
Structure-activity relationships of tubulysin analogues
Courter, Joel R., Hamilton, Joseph Z., Hendrick, Nathaniel R., Zaval, Margo, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.
Published in Bioorganic & medicinal chemistry letters (15.07.2020)
Published in Bioorganic & medicinal chemistry letters (15.07.2020)
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Journal Article
Ion selectivity and gating mechanisms of FNT channels
Waight, Andrew B, Czyzewski, Bryan K, Wang, Da-Neng
Published in Current opinion in structural biology (01.08.2013)
Published in Current opinion in structural biology (01.08.2013)
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Journal Article
Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation
Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.
Published in ChemMedChem (08.04.2021)
Published in ChemMedChem (08.04.2021)
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Journal Article
Front Cover: Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation (ChemMedChem 7/2021)
Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.
Published in ChemMedChem (08.04.2021)
Published in ChemMedChem (08.04.2021)
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Journal Article
Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics
Waight, Andrew B., Bargsten, Katja, Doronina, Svetlana, Steinmetz, Michel O., Sussman, Django, Prota, Andrea E., Komarova, Yulia
Published in PloS one (12.08.2016)
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Published in PloS one (12.08.2016)
Journal Article
Abstract 930: Targeted delivery of cytotoxic NAMPT inhibitors using antibody-drug conjugates
Neumann, Christopher S., Olivas, Kathleen C., Waight, Andrew B., Meyer, David, Loftus, Luke V., Zaval, Margo, Anderson, Martha E., Jin, Steven, Cochran, Julia H., Simmons, Jessica K., Pittman, Paul G., Lyon, Robert P., Senter, Peter D.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article