Nonclinical Pharmacokinetics, Disposition, and Drug-Drug Interaction Potential of a Novel d-Amino Acid Peptide Agonist of the Calcium-Sensing Receptor AMG 416 (Etelcalcetide)
Subramanian, Raju, Zhu, Xiaochun, Kerr, Savannah J, Esmay, Joel D, Louie, Steven W, Edson, Katheryne Z, Walter, Sarah, Fitzsimmons, Michael, Wagner, Mylo, Soto, Marcus, Pham, Roger, Wilson, Sarah F, Skiles, Gary L
Published in Drug metabolism and disposition (01.08.2016)
Published in Drug metabolism and disposition (01.08.2016)
Get full text
Journal Article
P450-mediated O-demethylated metabolite is responsible for rat hepatobiliary toxicity of pyridyltriazine-containing PI3K inhibitors
Subramanian, Raju, Aidasani, Divesh, Bailey, Keith, Branstetter, Dan, Everds, Nancy, Jiang, Jian, Norman, Mark H, Primack, Ronya, Skiles, Gary L, Soto, Irene, Stec, Markian M, Wagner, Mylo, Wu, Tian, Zhu, Xiaochun, Lebrec, Hervé
Published in Toxicological sciences (01.11.2014)
Published in Toxicological sciences (01.11.2014)
Get full text
Journal Article
Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies
Soto, Marcus, Pham, Roger, Almon, Valerie, Wagner, Mylo, Primack, Ronya, Ponce, Manuel, Meyer, James, James, Christopher A, Salyers, Kevin L, Retter, Marc W
Published in Bioanalysis (01.08.2014)
Published in Bioanalysis (01.08.2014)
Get full text
Journal Article
The Cytoprotective Effects of the Glycoprotein 130 Receptor-coupled Cytokine, Cardiotrophin-1, Require Activation of NF-κB
Craig, Rian, Wagner, Mylo, McCardle, Trevor, Craig, A. Grey, Glembotski, Christopher C.
Published in The Journal of biological chemistry (05.10.2001)
Published in The Journal of biological chemistry (05.10.2001)
Get full text
Journal Article