Loading…
Decoupling of Sleep-Dependent Cortical and Hippocampal Interactions in a Neurodevelopmental Model of Schizophrenia
Phillips, Keith G., Bartsch, Ullrich, McCarthy, Andrew P., Edgar, Dale M., Tricklebank, Mark D., Wafford, Keith A., Jones, Matt W.
Published in Neuron (Cambridge, Mass.) (08.11.2012)
Published in Neuron (Cambridge, Mass.) (08.11.2012)
Get full text
Journal Article
Loading…
Loading…
Loading…
Treating insomnia: Current and investigational pharmacological approaches
Ebert, Bjarke, Wafford, Keith A., Deacon, Stephen
Published in Pharmacology & therapeutics (Oxford) (01.12.2006)
Published in Pharmacology & therapeutics (Oxford) (01.12.2006)
Get full text
Journal Article
Loading…
Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders
Bruns, Robert F., Mitchell, Stephen N., Wafford, Keith A., Harper, Alex J., Shanks, Elaine A., Carter, Guy, O'Neill, Michael J., Murray, Tracey K., Eastwood, Brian J., Schaus, John M., Beck, James P., Hao, Junliang, Witkin, Jeffrey M., Li, Xia, Chernet, Eyassu, Katner, Jason S., Wang, Hong, Ryder, John W., Masquelin, Meghane E., Thompson, Linda K., Love, Patrick L., Maren, Deanna L., Falcone, Julie F., Menezes, Michelle M., Zhang, Linli, Yang, Charles R., Svensson, Kjell A.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
Get full text
Journal Article
Loading…
TaiNi: Maximizing research output whilst improving animals’ welfare in neurophysiology experiments
Jiang, Zhou, Huxter, John R., Bowyer, Stuart A., Blockeel, Anthony J., Butler, James, Imtiaz, Syed A., Wafford, Keith A., Phillips, Keith G., Tricklebank, Mark D., Marston, Hugh M., Rodriguez-Villegas, Esther
Published in Scientific reports (14.08.2017)
Published in Scientific reports (14.08.2017)
Get full text
Journal Article
Loading…
Imidazo[1,2-a]pyrimidines as Functionally Selective and Orally Bioavailable GABAAα2/α3 Binding Site Agonists for the Treatment of Anxiety Disorders
Goodacre, Simon C, Street, Leslie J, Hallett, David J, Crawforth, James M, Kelly, Sarah, Owens, Andrew P, Blackaby, Wesley P, Lewis, Richard T, Stanley, Joanna, Smith, Alison J, Ferris, Pushpinder, Sohal, Bindi, Cook, Susan M, Pike, Andrew, Brown, Nicola, Wafford, Keith A, Marshall, George, Castro, José L, Atack, John R
Published in Journal of medicinal chemistry (12.01.2006)
Published in Journal of medicinal chemistry (12.01.2006)
Get full text
Journal Article
Loading…
Growth factors regulate the survival and fate of cells derived from human neurospheres
Caldwell, Maeve A, He, Xiaoling, Wilkie, Neil, Pollack, Scott, Marshall, George, Wafford, Keith A., Svendsen, Clive N.
Published in Nature biotechnology (01.05.2001)
Published in Nature biotechnology (01.05.2001)
Get full text
Journal Article
Loading…
Selective Enhancement of Tonic GABAergic Inhibition in Murine Hippocampal Neurons by Low Concentrations of the Volatile Anesthetic Isoflurane
Caraiscos, Valerie B, Newell, J. Glen, You-Ten, Kong E, Elliott, Erin M, Rosahl, Thomas W, Wafford, Keith A, MacDonald, John F, Orser, Beverley A
Published in The Journal of neuroscience (29.09.2004)
Published in The Journal of neuroscience (29.09.2004)
Get full text
Journal Article
Loading…
REM sleep’s unique associations with corticosterone regulation, apoptotic pathways, and behavior in chronic stress in mice
Nollet, Mathieu, Hicks, Harriet, McCarthy, Andrew P., Wu, Huihai, Möller-Levet, Carla S., Laing, Emma E., Malki, Karim, Lawless, Nathan, Wafford, Keith A., Dijk, Derk-Jan, Winsky-Sommerer, Raphaelle
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.02.2019)
Get full text
Journal Article
Loading…
Loading…
The Dopamine D1 Receptor Positive Allosteric Modulator Mevidalen (LY3154207) Enhances Wakefulness in the Humanized D1 Mouse and in Sleep-Deprived Healthy Male Volunteers
McCarthy, Andrew P., Svensson, Kjell A., Shanks, Elaine, Brittain, Claire, Eastwood, Brian J., Kielbasa, William, Biglan, Kevin M., Wafford, Keith A.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
Get full text
Journal Article
Loading…
Loading…
Loading…
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
Kato, Akihiko S, Burris, Kevin D, Gardinier, Kevin M, Gernert, Douglas L, Porter, Warren J, Reel, Jon, Ding, Chunjin, Tu, Yuan, Schober, Douglas A, Lee, Matthew R, Heinz, Beverly A, Fitch, Thomas E, Gleason, Scott D, Catlow, John T, Yu, Hong, Fitzjohn, Stephen M, Pasqui, Francesca, Wang, He, Qian, Yuewei, Sher, Emanuele, Zwart, Ruud, Wafford, Keith A, Rasmussen, Kurt, Ornstein, Paul L, Isaac, John T R, Nisenbaum, Eric S, Bredt, David S, Witkin, Jeffrey M
Published in Nature medicine (01.12.2016)
Published in Nature medicine (01.12.2016)
Get full text
Journal Article
Loading…
Extrasynaptic GABAA Receptors of Thalamocortical Neurons: A Molecular Target for Hypnotics
Belelli, Delia, Peden, Dianne R, Rosahl, Thomas W, Wafford, Keith A, Lambert, Jeremy J
Published in The Journal of neuroscience (14.12.2005)
Published in The Journal of neuroscience (14.12.2005)
Get full text
Journal Article
Loading…
Phase-amplitude coupled persistent theta and gamma oscillations in rat primary motor cortex in vitro
Johnson, Nicholas W., Özkan, Mazhar, Burgess, Adrian P., Prokic, Emma J., Wafford, Keith A., O'Neill, Michael J., Greenhill, Stuart D., Stanford, Ian M., Woodhall, Gavin L.
Published in Neuropharmacology (01.06.2017)
Published in Neuropharmacology (01.06.2017)
Get full text
Journal Article
Loading…
Prevalence and influence of cys407 Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour
Wood, Christian M., Nicolas, Celine S., Choi, Sun-Lim, Roman, Erika, Nylander, Ingrid, Fernandez-Teruel, Alberto, Kiianmaa, Kalervo, Bienkowski, Przemyslaw, de Jong, Trynke R., Colombo, Giancarlo, Chastagnier, Denis, Wafford, Keith A., Collingridge, Graham L., Wildt, Sheryl J., Conway-Campbell, Becky L., Robinson, Emma S.J., Lodge, David
Published in Neuropharmacology (15.03.2017)
Published in Neuropharmacology (15.03.2017)
Get full text
Journal Article
Loading…
Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA A receptors and a homo‐oligomeric GABA receptor from Drosophila melanogaster
Priestley, Caroline M, Williamson, Elizabeth M, Wafford, Keith A, Sattelle, David B
Published in British journal of pharmacology (01.12.2003)
Published in British journal of pharmacology (01.12.2003)
Get full text
Journal Article
Loading…
γ-Aminobutyric Acid Type A Receptor β2 Subunit Mediates the Hypothermic Effect of Etomidate in Mice
Cirone, Jennifer, Rosahl, Thomas W., Reynolds, David S., Newman, Richard J., O'Meara, Gillian F., Hutson, Peter H., Wafford, Keith A.
Published in Anesthesiology (Philadelphia) (01.06.2004)
Published in Anesthesiology (Philadelphia) (01.06.2004)
Get full text
Journal Article