In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma
Younger, Nicholas T, Wilson, Mollie L, Martinez Lyons, Anabel, Jarman, Edward J, Meynert, Alison M, Grimes, Graeme R, Gournopanos, Konstantinos, Waddell, Scott H, Tennant, Peter A, Wilson, David H, Guest, Rachel V, Wigmore, Stephen J, Acosta, Juan Carlos, Kendall, Timothy J, Taylor, Martin S, Sproul, Duncan, Mill, Pleasantine, Boulter, Luke
Published in Cancer research (Chicago, Ill.) (15.04.2022)
Published in Cancer research (Chicago, Ill.) (15.04.2022)
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Journal Article
A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice
Ford, Matthew J., Yeyati, Patricia L., Mali, Girish R., Keighren, Margaret A., Waddell, Scott H., Mjoseng, Heidi K., Douglas, Adam T., Hall, Emma A., Sakaue-Sawano, Asako, Miyawaki, Atsushi, Meehan, Richard R., Boulter, Luke, Jackson, Ian J., Mill, Pleasantine, Mort, Richard L.
Published in Developmental cell (19.11.2018)
Published in Developmental cell (19.11.2018)
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Journal Article
A TGFβ-ECM-integrin signaling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease
Waddell, Scott H, Yao, Yuelin, Olaizola, Paula, Walker, Alexander, Jarman, Edward J, Gournopanos, Konstantinos, Gradinaru, Andreea, Christodoulou, Ersi, Gautier, Philippe, Boerrigter, Melissa M, Cadamuro, Massimiliano, Fabris, Luca, Drenth, Joost Ph, Kendall, Timothy J, Banales, Jesus M, Khamseh, Ava, Mill, Pleasantine, Boulter, Luke
Published in Science translational medicine (13.09.2023)
Published in Science translational medicine (13.09.2023)
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Journal Article
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis
O'Sullivan, Eoin D, Mylonas, Katie J, Xin, Cuiyan, Baird, David P, Carvalho, Cyril, Docherty, Marie-Helena, Campbell, Ross, Matchett, Kylie P, Waddell, Scott H, Walker, Alexander D, Gallagher, Kevin M, Jia, Siyang, Leung, Steve, Laird, Alexander, Wilflingseder, Julia, Willi, Michaela, Reck, Maximilian, Finnie, Sarah, Pisco, Angela, Gordon-Keylock, Sabrina, Medvinsky, Alexander, Boulter, Luke, Henderson, Neil C, Kirschner, Kristina, Chandra, Tamir, Conway, Bryan R, Hughes, Jeremy, Denby, Laura, Bonventre, Joseph V, Ferenbach, David A
Published in Science translational medicine (31.05.2023)
Published in Science translational medicine (31.05.2023)
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Journal Article
DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01
Jarman, Edward J., Horcas‐Lopez, Marta, Waddell, Scott H., MacMaster, Stephanie, Gournopanos, Konstantinos, Soong, Daniel Y. H., Musialik, Kamila I., Tsokkou, Panagiota, Ng, Minn‐E, Cambridge, William A., Wilson, David H., Kagey, Michael H., Newman, Walter, Pollard, Jeffrey W., Boulter, Luke
Published in Liver international (01.01.2023)
Published in Liver international (01.01.2023)
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Journal Article
Planar cell polarity is essential for the architectural patterning of the mammalian biliary tree
Raab, Michaela, Christodoulou, Ersi, Krishnankutty, Roopesh, Younger, Nicholas T, Gournopanos, Konstantinos, Alexander Von Kriegsheim, Waddell, Scott H, Boulter, Luke
Published in bioRxiv (20.11.2023)
Published in bioRxiv (20.11.2023)
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Primary cilia loss promotes reactivation of morphogenesis and cyst-fission through a deregulated TGFβ-ECM-Integrin axis in polycystic liver disease
Waddell, Scott H, Yao, Yuelin, Olaizola, Paula, Jarman, Edward J, Gournopanos, Konstantinos, Christodoulou, Ersi, Gautier, Philippe, Joost Ph Drenth, Kendall, Timothy J, Banales, Jesus M, Khamseh, Ava, Mill, Pleasantine, Boulter, Luke
Published in bioRxiv (08.04.2022)
Published in bioRxiv (08.04.2022)
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