Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways
Surrey, Lea F, Jain, Payal, Zhang, Bo, Straka, Joshua, Zhao, Xiaonan, Harding, Brian N, Resnick, Adam C, Storm, Phillip B, Buccoliero, Anna Maria, Genitori, Lorenzo, Li, Marilyn M, Waanders, Angela J, Santi, Mariarita
Published in Journal of neuropathology and experimental neurology (01.12.2019)
Published in Journal of neuropathology and experimental neurology (01.12.2019)
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Clinical utility of custom-designed NGS panel testing in pediatric tumors
Surrey, Lea F, MacFarland, Suzanne P, Chang, Fengqi, Cao, Kajia, Rathi, Komal S, Akgumus, Gozde T, Gallo, Daniel, Lin, Fumin, Gleason, Adam, Raman, Pichai, Aplenc, Richard, Bagatell, Rochelle, Minturn, Jane, Mosse, Yael, Santi, Mariarita, Tasian, Sarah K, Waanders, Angela J, Sarmady, Mahdi, Maris, John M, Hunger, Stephen P, Li, Marilyn M
Published in Genome medicine (28.05.2019)
Published in Genome medicine (28.05.2019)
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MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia
Jones, Courtney L., Gearheart, Christy M., Fosmire, Susan, Delgado-Martin, Cristina, Evensen, Nikki A., Bride, Karen, Waanders, Angela J., Pais, Faye, Wang, Jinhua, Bhatla, Teena, Bitterman, Danielle S., de Rijk, Simone R., Bourgeois, Wallace, Dandekar, Smita, Park, Eugene, Burleson, Tamara M., Madhusoodhan, Pillai Pallavi, Teachey, David T., Raetz, Elizabeth A., Hermiston, Michelle L., Müschen, Markus, Loh, Mignon L., Hunger, Stephen P., Zhang, Jinghui, Garabedian, Michael J., Porter, Christopher C., Carroll, William L.
Published in Blood (05.11.2015)
Published in Blood (05.11.2015)
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BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas
Olow, Aleksandra, Mueller, Sabine, Yang, Xiaodong, Hashizume, Rintaro, Meyerowitz, Justin, Weiss, William, Resnick, Adam C, Waanders, Angela J, Stalpers, Lukas J A, Berger, Mitchel S, Gupta, Nalin, James, C David, Petritsch, Claudia K, Haas-Kogan, Daphne A
Published in Clinical cancer research (01.11.2016)
Published in Clinical cancer research (01.11.2016)
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Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas
Ryall, Scott, Zapotocky, Michal, Fukuoka, Kohei, Nobre, Liana, Guerreiro Stucklin, Ana, Bennett, Julie, Siddaway, Robert, Li, Christopher, Pajovic, Sanja, Arnoldo, Anthony, Kowalski, Paul E., Johnson, Monique, Sheth, Javal, Lassaletta, Alvaro, Tatevossian, Ruth G., Orisme, Wilda, Qaddoumi, Ibrahim, Surrey, Lea F., Li, Marilyn M., Waanders, Angela J., Gilheeney, Stephen, Rosenblum, Marc, Bale, Tejus, Tsang, Derek S., Laperriere, Normand, Kulkarni, Abhaya, Ibrahim, George M., Drake, James, Dirks, Peter, Taylor, Michael D., Rutka, James T., Laughlin, Suzanne, Shroff, Manohar, Shago, Mary, Hazrati, Lili-Naz, D'Arcy, Colleen, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Bouffet, Eric, Karajannis, Matthias A., Santi, Mariarita, Ellison, David W., Tabori, Uri, Hawkins, Cynthia
Published in Cancer cell (13.04.2020)
Published in Cancer cell (13.04.2020)
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Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status
Roth, Jacquelyn J., Fierst, Tamara M., Waanders, Angela J., Yimei, Li, Biegel, Jaclyn A., Santi, Mariarita
Published in Journal of neuropathology and experimental neurology (01.04.2016)
Published in Journal of neuropathology and experimental neurology (01.04.2016)
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Data standards in pediatric oncology: Past, present, and future
Wyatt, Kirk D., Noyd, David H., Wood, Nicole M., Phillips, Charles A., Miller, Tamara P., Rubin, Elyssa M., Winestone, Lena E., Waanders, Angela J., Perentesis, John P., Aplenc, Richard
Published in Pediatric blood & cancer (01.02.2023)
Published in Pediatric blood & cancer (01.02.2023)
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Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways
Jain, Payal, Silva, Amanda, Han, Harry J, Lang, Shih-Shan, Zhu, Yuankun, Boucher, Katie, Smith, Tiffany E, Vakil, Aesha, Diviney, Patrick, Choudhari, Namrata, Raman, Pichai, Busch, Christine M, Delaney, Tim, Yang, Xiaodong, Olow, Aleksandra K, Mueller, Sabine, Haas-Kogan, Daphne, Fox, Elizabeth, Storm, Phillip B, Resnick, Adam C, Waanders, Angela J
Published in Oncotarget (17.10.2017)
Published in Oncotarget (17.10.2017)
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The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science
Lilly, Jena V., Rokita, Jo Lynne, Mason, Jennifer L., Patton, Tatiana, Stefankiewiz, Stephanie, Higgins, David, Trooskin, Gerri, Larouci, Carina A., Arya, Kamnaa, Appert, Elizabeth, Heath, Allison P., Zhu, Yuankun, Brown, Miguel A., Zhang, Bo, Farrow, Bailey K., Robins, Shannon, Morgan, Allison M., Nguyen, Thinh Q., Frenkel, Elizabeth, Lehmann, Kaitlin, Drake, Emily, Sullivan, Catherine, Plisiewicz, Alexa, Coleman, Noel, Patterson, Luke, Koptyra, Mateusz, Helili, Zeinab, Van Kuren, Nicholas, Young, Nathan, Kim, Meen Chul, Friedman, Christopher, Lubneuski, Alex, Blackden, Christopher, Williams, Marti, Baubet, Valerie, Tauhid, Lamiya, Galanaugh, Jamie, Boucher, Katie, Ijaz, Heba, Cole, Kristina A., Choudhari, Namrata, Santi, Mariarita, Moulder, Robert W., Waller, Jonathan, Rife, Whitney, Diskin, Sharon J., Mateos, Marion, Parsons, Donald W., Pollack, Ian F., Goldman, Stewart, Leary, Sarah, Caporalini, Chiara, Buccoliero, Anna Maria, Scagnet, Mirko, Haussler, David, Hanson, Derek, Firestein, Ron, Cain, Jason, Phillips, Joanna J., Gupta, Nalin, Mueller, Sabine, Grant, Gerald, Monje-Deisseroth, Michelle, Partap, Sonia, Greenfield, Jeffrey P., Hashizume, Rintaro, Smith, Amy, Zhu, Shida, Johnston, James M., Fangusaro, Jason R., Miller, Matthew, Wood, Matthew D., Gardner, Sharon, Carter, Claire L., Prolo, Laura M., Pisapia, Jared, Pehlivan, Katherine, Franson, Andrea, Niazi, Toba, Rubin, Josh, Abdelbaki, Mohamed, Ziegler, David S., Lindsay, Holly B., Stucklin, Ana Guerreiro, Gerber, Nicolas, Vaske, Olena M., Quinsey, Carolyn, Rood, Brian R., Nazarian, Javad, Raabe, Eric, Jackson, Eric M., Stapleton, Stacie, Lober, Robert M., Kram, David E., Koschmann, Carl, Storm, Phillip B., Lulla, Rishi R., Prados, Michael, Resnick, Adam C., Waanders, Angela J.
Published in Neoplasia (New York, N.Y.) (01.01.2023)
Published in Neoplasia (New York, N.Y.) (01.01.2023)
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Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response
Foster, Jessica B, Choudhari, Namrata, Perazzelli, Jessica, Storm, Julie, Hofmann, Ted J, Jain, Payal, Storm, Phillip B, Pardi, Norbert, Weissman, Drew, Waanders, Angela J, Grupp, Stephan A, Karikó, Katalin, Resnick, Adam C, Barrett, David M
Published in Human gene therapy (01.02.2019)
Published in Human gene therapy (01.02.2019)
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Kinetics of the Low-Temperature Pyrolysis of Polyethene, Polypropene, and Polystyrene Modeling, Experimental Determination, and Comparison with Literature Models and Data
Westerhout, R. W. J, Waanders, J, Kuipers, J. A. M, van Swaaij, W. P. M
Published in Industrial & engineering chemistry research (01.06.1997)
Published in Industrial & engineering chemistry research (01.06.1997)
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A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium
Mueller, Sabine, Jain, Payal, Liang, Winnie S., Kilburn, Lindsay, Kline, Cassie, Gupta, Nalin, Panditharatna, Eshini, Magge, Suresh N., Zhang, Bo, Zhu, Yuankun, Crawford, John R., Banerjee, Anu, Nazemi, Kellie, Packer, Roger J., Petritsch, Claudia K., Truffaux, Nathalene, Roos, Alison, Nasser, Sara, Phillips, Joanna J., Solomon, David, Molinaro, Annette, Waanders, Angela J., Byron, Sara A., Berens, Michael E., Kuhn, John, Nazarian, Javad, Prados, Michael, Resnick, Adam C.
Published in International journal of cancer (01.10.2019)
Published in International journal of cancer (01.10.2019)
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Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial
Mackay, Alan, Burford, Anna, Molinari, Valeria, Jones, David T.W., Izquierdo, Elisa, Brouwer-Visser, Jurriaan, Giangaspero, Felice, Haberler, Christine, Pietsch, Torsten, Jacques, Thomas S., Figarella-Branger, Dominique, Rodriguez, Daniel, Morgan, Paul S., Raman, Pichai, Waanders, Angela J., Resnick, Adam C., Massimino, Maura, Garrè, Maria Luisa, Smith, Helen, Capper, David, Pfister, Stefan M., Würdinger, Thomas, Tam, Rachel, Garcia, Josep, Thakur, Meghna Das, Vassal, Gilles, Grill, Jacques, Jaspan, Tim, Varlet, Pascale, Jones, Chris
Published in Cancer cell (14.05.2018)
Published in Cancer cell (14.05.2018)
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Pediatric low-grade gliomas: next biologically driven steps
Jones, David T W, Kieran, Mark W, Bouffet, Eric, Alexandrescu, Sanda, Bandopadhayay, Pratiti, Bornhorst, Miriam, Ellison, David, Fangusaro, Jason, Fisher, Michael J, Foreman, Nicholas, Fouladi, Maryam, Hargrave, Darren, Hawkins, Cynthia, Jabado, Nada, Massimino, Maura, Mueller, Sabine, Perilongo, Giorgio, Schouten van Meeteren, Antoinette Y N, Tabori, Uri, Warren, Katherine, Waanders, Angela J, Walker, David, Weiss, William, Witt, Olaf, Wright, Karen, Zhu, Yuan, Bowers, Daniel C, Pfister, Stefan M, Packer, Roger J
Published in Neuro-oncology (Charlottesville, Va.) (22.01.2018)
Published in Neuro-oncology (Charlottesville, Va.) (22.01.2018)
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CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles
Jain, P, Fierst, T M, Han, H J, Smith, T E, Vakil, A, Storm, P B, Resnick, A C, Waanders, A J
Published in Oncogene (09.11.2017)
Published in Oncogene (09.11.2017)
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The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial
Kilburn, Lindsay B., Khuong-Quang, Dong-Anh, Hansford, Jordan R., Landi, Daniel, van der Lugt, Jasper, Leary, Sarah E. S., Driever, Pablo Hernáiz, Bailey, Simon, Perreault, Sébastien, McCowage, Geoffrey, Waanders, Angela J., Ziegler, David S., Witt, Olaf, Baxter, Patricia A., Kang, Hyoung Jin, Hassall, Timothy E., Han, Jung Woo, Hargrave, Darren, Franson, Andrea T., Yalon Oren, Michal, Toledano, Helen, Larouche, Valérie, Kline, Cassie, Abdelbaki, Mohamed S., Jabado, Nada, Gottardo, Nicholas G., Gerber, Nicolas U., Whipple, Nicholas S., Segal, Devorah, Chi, Susan N., Oren, Liat, Tan, Enrica E. K., Mueller, Sabine, Cornelio, Izzy, McLeod, Lisa, Zhao, Xin, Walter, Ashley, Da Costa, Daniel, Manley, Peter, Blackman, Samuel C., Packer, Roger J., Nysom, Karsten
Published in Nature medicine (2024)
Published in Nature medicine (2024)
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Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1)
Fisher, Michael J., Jones, David T. W., Li, Yimei, Guo, Xiaofan, Sonawane, Poonam S., Waanders, Angela J., Phillips, Joanna J., Weiss, William A., Resnick, Adam C., Gosline, Sara, Banerjee, Jineta, Guinney, Justin, Gnekow, Astrid, Kandels, Daniela, Foreman, Nicholas K., Korshunov, Andrey, Ryzhova, Marina, Massimi, Luca, Gururangan, Sri, Kieran, Mark W., Wang, Zhihong, Fouladi, Maryam, Sato, Mariko, Øra, Ingrid, Holm, Stefan, Markham, Stephen J., Beck, Pengbo, Jäger, Natalie, Wittmann, Andrea, Sommerkamp, Alexander C., Sahm, Felix, Pfister, Stefan M., Gutmann, David H.
Published in Acta neuropathologica (01.04.2021)
Published in Acta neuropathologica (01.04.2021)
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Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers
Chang, Fengqi, Lin, Fumin, Cao, Kajia, Surrey, Lea F., Aplenc, Richard, Bagatell, Rochelle, Resnick, Adam C., Santi, Mariarita, Storm, Phillip B., Tasian, Sarah K., Waanders, Angela J., Hunger, Stephen P., Li, Marilyn M.
Published in The Journal of molecular diagnostics : JMD (01.09.2019)
Published in The Journal of molecular diagnostics : JMD (01.09.2019)
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A Phase I and Surgical Study of Ribociclib and Everolimus in Children with Recurrent or Refractory Malignant Brain Tumors: A Pediatric Brain Tumor Consortium Study
DeWire, Mariko D, Fuller, Christine, Campagne, Olivia, Lin, Tong, Pan, Haitao, Young Poussaint, Tina, Baxter, Patricia A, Hwang, Eugene I, Bukowinski, Andrew, Dorris, Kathleen, Hoffman, Lindsey, Waanders, Angela J, Karajannis, Matthias A, Stewart, Clinton F, Onar-Thomas, Arzu, Fouladi, Maryam, Dunkel, Ira J
Published in Clinical cancer research (01.05.2021)
Published in Clinical cancer research (01.05.2021)
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