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Broom, Daniel C, Matson, David J, Bradshaw, Elizabeth, Buck, Marianne E, Meade, Robin, Coombs, Susan, Matchett, Michele, Ford, Kristen K, Yu, Weifeng, Yuan, Jun, Sun, Synthia H, Ochoa, Ricardo, Krause, James E, Wustrow, David J, Cortright, Daniel N
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Published in Journal of medicinal chemistry (28.05.2020)
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Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors
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Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy
Jackson, Jeffrey J., Shibuya, Grant M., Ravishankar, Buvana, Adusumilli, Lavanya, Bradford, Delia, Brockstedt, Dirk G., Bucher, Cyril, Bui, Minna, Cho, Cynthia, Colas, Christoph, Cutler, Gene, Dukes, Adrian, Han, Xinping, Hu, Dennis X., Jacobson, Scott, Kassner, Paul D., Katibah, George E., Ko, Michelle Yoo Min, Kolhatkar, Urvi, Leger, Paul R., Ma, Anqi, Marshall, Lisa, Maung, Jack, Ng, Andrew A., Okano, Akinori, Pookot, Deepa, Poon, Daniel, Ramana, Chandru, Reilly, Maureen K., Robles, Omar, Schwarz, Jacob B., Shakhmin, Anton A., Shunatona, Hunter P., Sreenivasan, Raashi, Tivitmahaisoon, Parcharee, Xu, Mengshu, Zaw, Thant, Wustrow, David J., Zibinsky, Mikhail
Published in Journal of medicinal chemistry (13.10.2022)
Published in Journal of medicinal chemistry (13.10.2022)
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Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment
Jackson, Jeffrey J, Ketcham, John M, Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P, Bui, Minna H. T, Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X, Jacobson, Scott, Karbarz, Emily, Kassner, Paul D, Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K, Robles, Omar, Shunatona, Hunter P, Talay, Oezcan, Walker, James R, Wadsworth, Angela, Wustrow, David J, Zibinsky, Mikhail
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Oxadiazolone bioisosteres of pregabalin and gabapentin
Wustrow, David J., Belliotti, Thomas R., Capiris, Thomas, Kneen, Clare O., Bryans, Justin S., Field, Mark J., Williams, Dic, El-Kattan, Ayman, Buchholz, Lisa, Kinsora, Jack J., Lotarski, Susan M., Vartanian, Mark G., Taylor, Charles P., Donevan, Sean D., Thorpe, Andrew J., Schwarz, Jacob B.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T-reg Trafficking into the Tumor Microenvironment
Jackson, Jeffrey J., Ketcham, John M., Younai, Ashkaan, Abraham, Betty, Biannic, Berenger, Beck, Hilary P., Bui, Minna H. T., Chian, David, Cutler, Gene, Diokno, Raymond, Hu, Dennis X., Jacobson, Scott, Karbarz, Emily, Kassner, Paul D., Marshall, Lisa, McKinnell, Jenny, Meleza, Cesar, Okal, Abood, Pookot, Deepa, Reilly, Maureen K., Robles, Omar, Shunatona, Hunter P., Talay, Oezcan, Walker, James R., Wadsworth, Angela, Wustrow, David J., Zibinsky, Mikhail
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases
Hu, Lain-Yen, Boxer, Peter A., Kesten, Suzanne R., Lei, Huangshu J., Wustrow, David J., Moreland, David W., Zhang, Liming, Ahn, Kay, Ryder, Todd R., Liu, Xiaohong, Rubin, John R., Fahnoe, Kelly, Carroll, Richard T., Dutta, Satavisha, Fahnoe, Douglass C., Probert, Albert W., Roof, Robin L., Rafferty, Michael F., Kostlan, Catherine R., Scholten, Jeffrey D., Hood, Molly, Ren, Xiao-Dan, Schielke, Gerald P., Su, Ti-Zhi, Taylor, Charles P., Mistry, Anil, McConnell, Patrick, Hasemann, Charles, Ohren, Jeffrey
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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Structure−Activity Relationships of Pregabalin and Analogues That Target the α2-δ Protein
Belliotti, Thomas R, Capiris, Thomas, Ekhato, I. Victor, Kinsora, Jack J, Field, Mark J, Heffner, Thomas G, Meltzer, Leonard T, Schwarz, Jacob B, Taylor, Charles P, Thorpe, Andrew J, Vartanian, Mark G, Wise, Lawrence D, Zhi-Su, Ti, Weber, Mark L, Wustrow, David J
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
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Discovery of a novel potent GABA(B) receptor agonist
Xu, Feng, Peng, Ge, Phan, Thu, Dilip, Usha, Chen, Jian Lu, Chernov-Rogan, Tania, Zhang, Xuexiang, Grindstaff, Kent, Annamalai, Thamil, Koller, Kerry, Gallop, Mark A, Wustrow, David J
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Discovery of a novel potent GABAB receptor agonist
Xu, Feng, Peng, Ge, Phan, Thu, Dilip, Usha, Chen, Jian Lu, Chernov-Rogan, Tania, Zhang, Xuexiang, Grindstaff, Kent, Annamalai, Thamil, Koller, Kerry, Gallop, Mark A, Wustrow, David J
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Year of Publication 19.07.2022
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JACKSON JEFFREY J, YOUNAI ASHKAAN, BUCHER CYRIL, SHIBUYA GRANT, DAVIDSON JAMES P, ZIBINSKY MIKHAIL, KO MICHELLE YOO MIN, WUSTROW DAVID J
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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Novel Cyclopropyl β-Amino Acid Analogues of Pregabalin and Gabapentin That Target the α2-δ Protein
Schwarz, Jacob B, Gibbons, Sian E, Graham, Shelley R, Colbry, Norman L, Guzzo, Peter R, Le, Van-Duc, Vartanian, Mark G, Kinsora, Jack J, Lotarski, Susan M, Li, Zheng, Dickerson, Melvin R, Su, Ti-Zhi, Weber, Mark L, El-Kattan, Ayman, Thorpe, Andrew J, Donevan, Sean D, Taylor, Charles P, Wustrow, David J
Published in Journal of medicinal chemistry (21.04.2005)
Published in Journal of medicinal chemistry (21.04.2005)
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1-Benzylbenzimidazoles : The discovery of a novel series of bradykinin B1 receptor antagonists
QIN GUO, CHANDRASEKHAR, Jayaraman, BROOM, Daniel, KERSHAW, Mark T, SIMMERMACHER-MAYER, Jean, YAO PENG, HODGETTS, Kevin J, IHLE, David, WUSTROW, David J, CHENARD, Bertrand L, KRAUSE, James E, HUTCHISON, Alan, ALDERMAN, Dawn, CHENG, Charles, CORTRIGHT, Daniel
Published in Bioorganic & medicinal chemistry letters (15.09.2008)
Published in Bioorganic & medicinal chemistry letters (15.09.2008)
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Aminopyrazine CB1 receptor inverse agonists
Wustrow, David J., Maynard, George D., Yuan, Jun, Zhao, He, Mao, Jianmin, Guo, Qin, Kershaw, Mark, Hammer, Jack, Brodbeck, Robbin M., Near, Kristen E., Zhou, Dan, Beers, David S., Chenard, Bertrand L., Krause, James E., Hutchison, Alan J.
Published in Bioorganic & medicinal chemistry (01.06.2008)
Published in Bioorganic & medicinal chemistry (01.06.2008)
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Isoindolinone enantiomers having affinity for the dopamine D4 receptor
BELLIOTTI, T. R, BRINK, W. A, WISE, L. D, KESTEN, S. R, RUBIN, J. R, WUSTROW, D. J, ZOSKI, K. T, WHETZEL, S. Z, CORBIN, A. E, PUGSLEY, T. A, HEFFNER, T. G
Published in Bioorganic & medicinal chemistry letters (16.06.1998)
Published in Bioorganic & medicinal chemistry letters (16.06.1998)
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Heteroaromatic side-chain analogs of pregabalin
Schelkun, Robert M., Yuen, Po-wai, Wustrow, David J., Kinsora, Jack, Su, Ti-Zhi, Vartanian, Mark G.
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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