Macrophage function in obesity-induced inflammation and insulin resistance
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Book Review
Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation
Chaudhry, Ashutosh, Samstein, Robert M., Treuting, Piper, Liang, Yuqiong, Pils, Marina C., Heinrich, Jan-Michael, Jack, Robert S., Wunderlich, F. Thomas, Brüning, Jens C., Müller, Werner, Rudensky, Alexander Y.
Published in Immunity (Cambridge, Mass.) (22.04.2011)
Published in Immunity (Cambridge, Mass.) (22.04.2011)
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Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between Obesity and Inflammation-Driven Liver and Colorectal Cancers
Kern, Lara, Mittenbühler, Melanie J, Vesting, Anna Juliane, Ostermann, Anna Lena, Wunderlich, Claudia Maria, Wunderlich, F Thomas
Published in Cancers (27.12.2018)
Published in Cancers (27.12.2018)
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Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance
Turpin, Sarah M., Nicholls, Hayley T., Willmes, Diana M., Mourier, Arnaud, Brodesser, Susanne, Wunderlich, Claudia M., Mauer, Jan, Xu, Elaine, Hammerschmidt, Philipp, Brönneke, Hella S., Trifunovic, Aleksandra, LoSasso, Giuseppe, Wunderlich, F. Thomas, Kornfeld, Jan-Wilhelm, Blüher, Matthias, Krönke, Martin, Brüning, Jens C.
Published in Cell metabolism (07.10.2014)
Published in Cell metabolism (07.10.2014)
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Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism
Borgmann, Diba, Ciglieri, Elisa, Biglari, Nasim, Brandt, Claus, Cremer, Anna Lena, Backes, Heiko, Tittgemeyer, Marc, Wunderlich, F. Thomas, Brüning, Jens C., Fenselau, Henning
Published in Cell metabolism (06.07.2021)
Published in Cell metabolism (06.07.2021)
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Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance
Xu, Elaine, Pereira, Mafalda M. A., Karakasilioti, Ismene, Theurich, Sebastian, Al-Maarri, Mona, Rappl, Gunter, Waisman, Ari, Wunderlich, F. Thomas, Brüning, Jens C.
Published in Nature communications (03.05.2017)
Published in Nature communications (03.05.2017)
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IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
Timper, Katharina, Denson, Jesse Lee, Steculorum, Sophie Marie, Heilinger, Christian, Engström-Ruud, Linda, Wunderlich, Claudia Maria, Rose-John, Stefan, Wunderlich, F. Thomas, Brüning, Jens Claus
Published in Cell reports (Cambridge) (11.04.2017)
Published in Cell reports (Cambridge) (11.04.2017)
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IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions
Croxford, Andrew L., Karbach, Susanne, Kurschus, Florian C., Wörtge, Simone, Nikolaev, Alexei, Yogev, Nir, Klebow, Sabrina, Schüler, Rebecca, Reissig, Sonja, Piotrowski, Carolin, Brylla, Elke, Bechmann, Ingo, Scheller, Jürgen, Rose-John, Stefan, Thomas Wunderlich, F., Münzel, Thomas, von Stebut, Esther, Waisman, Ari
Published in Journal of investigative dermatology (01.03.2014)
Published in Journal of investigative dermatology (01.03.2014)
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LYN Kinase in the Tumor Microenvironment Is Essential for the Progression of Chronic Lymphocytic Leukemia
Nguyen, Phuong-Hien, Fedorchenko, Oleg, Rosen, Natascha, Koch, Maximilian, Barthel, Romy, Winarski, Tomasz, Florin, Alexandra, Wunderlich, F. Thomas, Reinart, Nina, Hallek, Michael
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C, Ruud, Johan, Nguyen, Khoa D, Theurich, Sebastian, Hausen, A Christine, Schmitz, Joel, Brönneke, Hella S, Estevez, Emma, Allen, Tamara L, Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A, Chawla, Ajay, Wunderlich, F Thomas, Brüning, Jens C
Published in Nature immunology (01.05.2014)
Published in Nature immunology (01.05.2014)
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NK cells link obesity-induced adipose stress to inflammation and insulin resistance
Wensveen, Felix M, Jelenčić, Vedrana, Valentić, Sonja, Šestan, Marko, Wensveen, Tamara Turk, Theurich, Sebastian, Glasner, Ariella, Mendrila, Davor, Štimac, Davor, Wunderlich, F Thomas, Brüning, Jens C, Mandelboim, Ofer, Polić, Bojan
Published in Nature immunology (01.04.2015)
Published in Nature immunology (01.04.2015)
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Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment
Wunderlich, Claudia M., Ackermann, P. Justus, Ostermann, Anna Lena, Adams-Quack, Petra, Vogt, Merly C., Tran, My-Ly, Nikolajev, Alexei, Waisman, Ari, Garbers, Christoph, Theurich, Sebastian, Mauer, Jan, Hövelmeyer, Nadine, Wunderlich, F. Thomas
Published in Nature communications (25.04.2018)
Published in Nature communications (25.04.2018)
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AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue
Steculorum, Sophie M., Ruud, Johan, Karakasilioti, Ismene, Backes, Heiko, Engström Ruud, Linda, Timper, Katharina, Hess, Martin E., Tsaousidou, Eva, Mauer, Jan, Vogt, Merly C., Paeger, Lars, Bremser, Stephan, Klein, Andreas C., Morgan, Donald A., Frommolt, Peter, Brinkkötter, Paul T., Hammerschmidt, Philipp, Benzing, Thomas, Rahmouni, Kamal, Wunderlich, F. Thomas, Kloppenburg, Peter, Brüning, Jens C.
Published in Cell (24.03.2016)
Published in Cell (24.03.2016)
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Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling
Nagao, Hirofumi, Cai, Weikang, Brandão, Bruna B, Wewer Albrechtsen, Nicolai J, Steger, Martin, Gattu, Arijeet K, Pan, Hui, Dreyfuss, Jonathan M, Wunderlich, F Thomas, Mann, Matthias, Kahn, C Ronald
Published in The Journal of clinical investigation (15.02.2023)
Published in The Journal of clinical investigation (15.02.2023)
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Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity
Xiao, Xing, Yeghiazaryan, Gagik, Hess, Simon, Klemm, Paul, Sieben, Anna, Kleinridders, André, Morgan, Donald A., Wunderlich, F. Thomas, Rahmouni, Kamal, Kong, Dong, Scammell, Thomas E., Lowell, Bradford B., Kloppenburg, Peter, Brüning, Jens C., Hausen, A. Christine
Published in Nature communications (02.09.2021)
Published in Nature communications (02.09.2021)
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Signaling through the Adaptor Molecule MyD88 in CD4+ T Cells Is Required to Overcome Suppression by Regulatory T Cells
Schenten, Dominik, Nish, Simone A., Yu, Shuang, Yan, Xiting, Lee, Heung Kyu, Brodsky, Igor, Pasman, Lesley, Yordy, Brian, Wunderlich, F. Thomas, Brüning, Jens C., Zhao, Hongyu, Medzhitov, Ruslan
Published in Immunity (Cambridge, Mass.) (16.01.2014)
Published in Immunity (Cambridge, Mass.) (16.01.2014)
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Consistently Simulating a Wide Range of Atmospheric Scenarios for K2-18b with a Flexible Radiative Transfer Module
Scheucher, Markus, Wunderlich, F., Grenfell, J. L., Godolt, M., Schreier, F., Kappel, D., Haus, R., Herbst, K., Rauer, H.
Published in The Astrophysical journal (01.07.2020)
Published in The Astrophysical journal (01.07.2020)
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MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity
Kleinridders, André, Schenten, Dominik, Könner, A. Christine, Belgardt, Bengt F., Mauer, Jan, Okamura, Tomoo, Wunderlich, F. Thomas, Medzhitov, Ruslan, Brüning, Jens C.
Published in Cell metabolism (01.10.2009)
Published in Cell metabolism (01.10.2009)
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Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria
Merkwirth, Carsten, Dargazanli, Sascha, Tatsuta, Takashi, Geimer, Stefan, Löwer, Beatrix, Wunderlich, F Thomas, von Kleist-Retzow, Jürgen-Christoph, Waisman, Ari, Westermann, Benedikt, Langer, Thomas
Published in Genes & development (15.02.2008)
Published in Genes & development (15.02.2008)
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Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
Wunderlich, F. Thomas, Brönneke, Hella S, Brüning, Jens C, Böttger, Thomas, Seibler, Jost, Braun, Thomas, Krüger, Markus, Kashkar, Hamid, Olkkonen, Vesa M, Jordan, Sabine D, Willmes, Diana M, Merkwirth, Carsten, Redemann, Nora
Published in Nature cell biology (01.04.2011)
Published in Nature cell biology (01.04.2011)
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