Hesperetin-5,7,3'- O -Trimethylether Dually Inhibits Phosphodiesterase 3/4 and Methacholine-Induced Airway Hyperresponsiveness in Sensitized and Challenged Mice
Shih, Chung-Hung, Wang, Wen-Hung, Chen, Chi-Ming, Ko, Wun-Chang
Published in Drug design, development and therapy (01.02.2020)
Published in Drug design, development and therapy (01.02.2020)
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Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts
Shih, Chwen-Ming, Ko, Wun-Chang, Wu, Jui-Sheng, Wei, Yau-Huei, Wang, Leng-Fang, Chang, E-E., Lo, Tsui-Yun, Cheng, Huey-Hwa, Chen, Chien-Tsu
Published in Journal of cellular biochemistry (01.02.2004)
Published in Journal of cellular biochemistry (01.02.2004)
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Hesperetin-5,7,3'-O-triacetate suppresses airway hyperresponsiveness in ovalbumin-sensitized and challenged mice without reversing xylazine/ketamine-induced anesthesia in normal mice
Yang, You-Lan, Chen, Chi-Li, Chen, Chi-Ming, Ko, Wun-Chang
Published in BMC pharmacology & toxicology (30.05.2017)
Published in BMC pharmacology & toxicology (30.05.2017)
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Inhibitory Effects of Hesperetin Derivatives on Guinea Pig Phosphodiesterases and Their Ratios Between High- and Low-Affinity Rolipram Binding
Hsu, Hsin-Te, Wang, Wen-Hung, Han, Cheng-Ying, Chen, Chun-Nan, Chen, Chi-Ming, Ko, Wun-Chang
Published in Journal of pharmaceutical sciences (01.07.2013)
Published in Journal of pharmaceutical sciences (01.07.2013)
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Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
Ko, Wun-Chang, Lin, Ling-Hung, Shen, Hsin-Yi, Lai, Chi-Yin, Chen, Chien-Ming, Shih, Chung-Hung
Published in Evidence-based complementary and alternative medicine (01.01.2011)
Published in Evidence-based complementary and alternative medicine (01.01.2011)
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Journal Article
Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio
Yang, You-Lan, Hsu, Hsin-Te, Wang, Kuo-Hsien, Han, Cheng-Ying, Chen, Chien-Ming, Chen, Chi-Ming, Ko, Wun-Chang
Published in Journal of biomedical science (11.11.2011)
Published in Journal of biomedical science (11.11.2011)
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Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia
Chen, Chien-Ming, Lai, Chi-Yin, Wang, Kuo-Hsien, Hsu, Hsin-Te, Lin, Ling-Hung, Shih, Chung-Hung, Ko, Wun-Chang
Published in Evidence-based complementary and alternative medicine (01.01.2012)
Published in Evidence-based complementary and alternative medicine (01.01.2012)
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Journal Article
Hesperidin-3′-O-Methylether Is More Potent than Hesperidin in Phosphodiesterase Inhibition and Suppression of Ovalbumin-Induced Airway Hyperresponsiveness
Chen, Chien-Ming, Wang, Chao-Sian, Wang, Kuo-Hsien, Hsu, Hsin-Te, Yang, You-Lan, Ko, Wun-Chang
Published in Evidence-based complementary and alternative medicine (01.01.2012)
Published in Evidence-based complementary and alternative medicine (01.01.2012)
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Journal Article
Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [3H]-rolipram binding in guinea pig tissues
Chan, Agnes L.-F., Huang, Hui-Lin, Chien, Hui-Chi, Chen, Chi-Ming, Lin, Chun-Nan, Ko, Wun-Chang
Published in Investigational new drugs (01.10.2008)
Published in Investigational new drugs (01.10.2008)
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S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
Lin, Yun-Lian, Chen, Chien-Ming, Huang, Tzu-Jung, Shih, Chung-Hung, Ko, Wun-Chang
Published in Evidence-based complementary and alternative medicine (01.01.2011)
Published in Evidence-based complementary and alternative medicine (01.01.2011)
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Journal Article
Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells
Wang, Sheng-Hao, Shih, Yung-Luen, Kuo, Tai-Chin, Ko, Wun-Chang, Shih, Chwen-Ming
Published in Toxicological sciences (01.03.2009)
Published in Toxicological sciences (01.03.2009)
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Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets
Sheu, J R, Lee, C R, Lin, C H, Hsiao, G, Ko, W C, Chen, Y C, Yen, M H
Published in Thrombosis and haemostasis (01.05.2000)
Published in Thrombosis and haemostasis (01.05.2000)
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Suppressive effects of 3-O-methylquercetin on ovalbumin-induced airway hyperresponsiveness
Ko, Wun-Chang, Shih, Chwen-Ming, Chen, Mei-Chun, Lai, Ya-Hsin, Chen, Jun-Hao, Chen, Chien-Ming, Lin, Chun-Nan
Published in Planta medica (01.12.2004)
Published in Planta medica (01.12.2004)
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Mechanisms of relaxant action of 3-O-methylquercetin in isolated guinea pig trachea
Ko, Wun-Chang, Wang, Han-Lang, Lei, Chien-Bang, Shih, Chih-Hsien, Chung, Mei-Ing, Lin, Chung-Nan
Published in Planta medica (01.01.2002)
Published in Planta medica (01.01.2002)
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