Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
Huang, Xu, Wullschleger, Stephan, Shpiro, Natalia, McGuire, Victoria A, Sakamoto, Kei, Woods, Yvonne L, McBurnie, Wendy, Fleming, Stewart, Alessi, Dario R
Published in Biochemical journal (01.06.2008)
Published in Biochemical journal (01.06.2008)
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Journal Article
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
Pearce, Laura R, Sommer, Eeva M, Sakamoto, Kei, Wullschleger, Stephan, Alessi, Dario R
Published in Biochemical journal (15.05.2011)
Published in Biochemical journal (15.05.2011)
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Journal Article
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
Pearce, Laura R, Huang, Xu, Boudeau, Jérôme, Pawłowski, Rafał, Wullschleger, Stephan, Deak, Maria, Ibrahim, Adel F M, Gourlay, Robert, Magnuson, Mark A, Alessi, Dario R
Published in Biochemical journal (01.08.2007)
Published in Biochemical journal (01.08.2007)
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Journal Article
Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control
Loewith, Robbie, Jacinto, Estela, Wullschleger, Stephan, Lorberg, Anja, Crespo, José L., Bonenfant, Débora, Oppliger, Wolfgang, Jenoe, Paul, Hall, Michael N.
Published in Molecular cell (01.09.2002)
Published in Molecular cell (01.09.2002)
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Journal Article
Molecular Organization of Target of Rapamycin Complex 2
Wullschleger, Stephan, Loewith, Robbie, Oppliger, Wolfgang, Hall, Michael N.
Published in The Journal of biological chemistry (02.09.2005)
Published in The Journal of biological chemistry (02.09.2005)
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Journal Article
Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV + Cancers
Galliverti, Gabriele, Wullschleger, Stephan, Tichet, Mélanie, Murugan, Dhaarini, Zangger, Nadine, Horton, Wesley, Korman, Alan J, Coussens, Lisa M, Swartz, Melody A, Hanahan, Douglas
Published in Cancer immunology research (01.01.2020)
Published in Cancer immunology research (01.01.2020)
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Journal Article
Tor2 Directly Phosphorylates the AGC Kinase Ypk2 To Regulate Actin Polarization
Kamada, Yoshiaki, Fujioka, Yuko, Suzuki, Nobuo N., Inagaki, Fuyuhiko, Wullschleger, Stephan, Loewith, Robbie, Hall, Michael N., Ohsumi, Yoshinori
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Journal Article
Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance
Bayascas, Jose R., Wullschleger, Stephan, Sakamoto, Kei, García-Martínez, Juan M., Clacher, Carol, Komander, David, van Aalten, Daan M. F., Boini, Krishna M., Lang, Florian, Lipina, Christopher, Logie, Lisa, Sutherland, Calum, Chudek, John A., van Diepen, Janna A., Voshol, Peter J., Lucocq, John M., Alessi, Dario R.
Published in Molecular and Cellular Biology (01.05.2008)
Published in Molecular and Cellular Biology (01.05.2008)
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Journal Article
Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
Tichet, Mélanie, Wullschleger, Stephan, Chryplewicz, Agnieszka, Fournier, Nadine, Marcone, Rachel, Kauzlaric, Annamaria, Homicsko, Krisztian, Deak, Laura Codarri, Umaña, Pablo, Klein, Christian, Hanahan, Douglas
Published in Immunity (Cambridge, Mass.) (10.01.2023)
Published in Immunity (Cambridge, Mass.) (10.01.2023)
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Journal Article
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 + T cells
Codarri Deak, Laura, Nicolini, Valeria, Hashimoto, Masao, Karagianni, Maria, Schwalie, Petra C, Lauener, Laura, Varypataki, Eleni Maria, Richard, Marine, Bommer, Esther, Sam, Johannes, Joller, Stefanie, Perro, Mario, Cremasco, Floriana, Kunz, Leo, Yanguez, Emilio, Hüsser, Tamara, Schlenker, Ramona, Mariani, Marisa, Tosevski, Vinko, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Colombetti, Sara, Gueripel, Xavier, Wullschleger, Stephan, Tichet, Melanie, Hanahan, Douglas, Kissick, Haydn T, Leclair, Stephane, Freimoser-Grundschober, Anne, Seeber, Stefan, Teichgräber, Volker, Ahmed, Rafi, Klein, Christian, Umaña, Pablo
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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Journal Article
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
Sadanandam, Anguraj, Lyssiotis, Costas A, Homicsko, Krisztian, Collisson, Eric A, Gibb, William J, Wullschleger, Stephan, Ostos, Liliane C Gonzalez, Lannon, William A, Grotzinger, Carsten, Del Rio, Maguy, Lhermitte, Benoit, Olshen, Adam B, Wiedenmann, Bertram, Cantley, Lewis C, Gray, Joe W, Hanahan, Douglas
Published in Nature medicine (01.05.2013)
Published in Nature medicine (01.05.2013)
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Journal Article
Abstract 71: The immunocytokine PD1-IL2v overcomes immune checkpoint resistance, and combination with an anti-PD-L1 antibody further enhances its anti-tumor activity
Wullschleger, Stephan, Tichet, Mélanie, Codarri-Deak, Laura, Umana, Pablo, Klein, Christian, Hanahan, Douglas
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression
Saghafinia, Sadegh, Homicsko, Krisztian, Di Domenico, Annunziata, Wullschleger, Stephan, Perren, Aurel, Marinoni, Ilaria, Ciriello, Giovanni, Michael, Iacovos P, Hanahan, Douglas
Published in Cancer discovery (01.10.2021)
Published in Cancer discovery (01.10.2021)
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Journal Article
A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics
Sadanandam, Anguraj, Wullschleger, Stephan, Lyssiotis, Costas A, Grötzinger, Carsten, Barbi, Stefano, Bersani, Samantha, Körner, Jan, Wafy, Ismael, Mafficini, Andrea, Lawlor, Rita T, Simbolo, Michele, Asara, John M, Bläker, Hendrik, Cantley, Lewis C, Wiedenmann, Bertram, Scarpa, Aldo, Hanahan, Douglas
Published in Cancer discovery (01.12.2015)
Published in Cancer discovery (01.12.2015)
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Journal Article
MP0533: A Multispecific Darpin CD3 Engager Targeting CD33, CD123, and CD70 for the Treatment of AML and MDS Designed to Selectively Target Leukemic Stem Cells
Bianchi, Matteo, Reichen, Christian, Fischer, Stefanie, Grübler, Yvonne, Eggenschwiler, Aline, Marpakwar, Rajlakshmi, Looser, Thamar, Spitzli, Patricia, Herzog, Christel, Villemagne, Denis, Kaufmann, Yvonne, Auge, Alienor, Hänggi, Martin, Ali, Waleed, Lekishvili, Tamara, Frasconi, Teresa, Wullschleger, Stephan, Zitt, Christof, Franchini, Marco, Croset, Amelie, Watson, Randall, Kirkin, Vladimir, Luethi, Ursina, Ochsenbein, Adrian, Riether, Carsten, Steiner, Daniel, Leupin, Nicolas, Goubier, Anne
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice
Galliverti, Gabriele, Tichet, Mélanie, Domingos-Pereira, Sonia, Hauert, Sylvie, Nardelli-Haefliger, Denise, Swartz, Melody A, Hanahan, Douglas, Wullschleger, Stephan
Published in Cancer immunology research (01.11.2018)
Published in Cancer immunology research (01.11.2018)
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Journal Article
Vagococcus teuberi sp. nov., isolated from the Malian artisanal sour milk fènè
Wullschleger, Stephan, Jans, Christoph, Seifert, Clelia, Baumgartner, Sarah, Lacroix, Christophe, Bonfoh, Bassirou, Stevens, Marc J.A., Meile, Leo
Published in Systematic and applied microbiology (01.03.2018)
Published in Systematic and applied microbiology (01.03.2018)
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