Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8
Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng-Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.04.2016)
Published in Proteins, structure, function, and bioinformatics (01.04.2016)
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A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors
Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark
Published in Cancer research (Chicago, Ill.) (01.07.2016)
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Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti–programmed cell death protein-1 (PD-1) antibody, in human cancer models
DeAngelis, Nikki, Ferrante, Catherine, Powers, Gordon, Sendecki, Jocelyn, Mattson, Bethany, Pizutti, Darlene, Packman, Kathryn, Wang, Weirong, Trouba, Kevin, Nanjunda, Rupesh, Wheeler, John, Brittingham, Ray, Wu, Sheng-Jiun, Luo, Jinquan, Lorenzi, Matthew V., Verona, Raluca I.
Published in Cancer chemotherapy and pharmacology (01.04.2022)
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"Stapling" scFv for multispecific biotherapeutics of superior properties
Boucher, Lauren E, Prinslow, Elisabeth Geyer, Feldkamp, Michael, Yi, Fang, Nanjunda, Rupesh, Wu, Sheng-Jiun, Liu, Tun, Lacy, Eilyn R, Jacobs, Steven, Kozlyuk, Natalia, Del Rosario, Brian, Wu, Bingyuan, Aquino, Patricia, Davidson, Robert C, Heyne, Samantha, Mazzanti, Nicholas, Testa, James, Diem, Michael D, Gorre, Elsa, Mahan, Andrew, Nanda, Hirsh, Gunawardena, Harsha P, Gervais, Alexis, Armstrong, Anthony A, Teplyakov, Alexey, Huang, Chichi, Zwolak, Adam, Chowdhury, Partha, Cheung, Wan Cheung, Luo, Jinquan
Published in mAbs (2023)
Published in mAbs (2023)
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Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab
Luo, Jinquan, Wu, Sheng-Jiun, Lacy, Eilyn R., Orlovsky, Yevgeniya, Baker, Audrey, Teplyakov, Alexey, Obmolova, Galina, Heavner, George A., Richter, Hans-Thomas, Benson, Jacqueline
Published in Journal of molecular biology (08.10.2010)
Published in Journal of molecular biology (08.10.2010)
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Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure
Luo, Jinquan, Obmolova, Galina, Malia, Thomas J., Wu, Sheng-Jiun, Duffy, Karen E., Marion, James D., Bell, Jessica K., Ge, Peng, Zhou, Z. Hong, Teplyakov, Alexey, Zhao, Yonghong, Lamb, Roberta J., Jordan, Jarrat L., San Mateo, Lani R., Sweet, Raymond W., Gilliland, Gary L.
Published in Journal of molecular biology (03.08.2012)
Published in Journal of molecular biology (03.08.2012)
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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality
Tam, Susan, McCarthy, Stephen, Armstrong, Anthony, Somani, Sandeep, Wu, Sheng-Jiun, Liu, Xuesong, Gervais, Alexis, Ernst, Robin, Saro, Dorina, Decker, Rose, Luo, Jinquan, Gilliland, Gary, Chiu, Mark, Scallon, Bernard
Published in Antibodies (Basel) (01.09.2017)
Published in Antibodies (Basel) (01.09.2017)
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Structure of the EMMPRIN N-terminal domain 1: Dimerization via β-strand swapping
Luo, Jinquan, Teplyakov, Alexey, Obmolova, Galina, Malia, Thomas, Wu, Sheng-Jiun, Beil, Eric, Baker, Audrey, Swencki-Underwood, Bethany, Zhao, Yonghong, Sprenkle, Justin, Dixon, Ken, Sweet, Raymond, Gilliland, Gary L.
Published in Proteins, structure, function, and bioinformatics (01.12.2009)
Published in Proteins, structure, function, and bioinformatics (01.12.2009)
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Probing the solution structure of tumor necrosis factor-α homotrimer and heterotrimer after complex perturbation using electrospray ionization mass spectrometry
Beil, Eric J., Heavner, George A., Wu, Sheng-Jiun, Nemeth, Jennifer F.
Published in Journal of molecular recognition (01.03.2012)
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Mechanisms of self-association of a human monoclonal antibody CNTO607
Bethea, Deidra, Wu, Sheng-Jiun, Luo, Jinquan, Hyun, Linus, Lacy, Eilyn R., Teplyakov, Alexey, Jacobs, Steven A., O'Neil, Karyn T., Gilliland, Gary L., Feng, Yiqing
Published in Protein engineering, design and selection (01.10.2012)
Published in Protein engineering, design and selection (01.10.2012)
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A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody
Fisher, Paul W, Brigham-Burke, Michael, Wu, Sheng-Jiun, Luo, Jinquan, Carton, Jill, Staquet, Kim, Gao, Wei, Jackson, Sheila, Bethea, Deidra, Chen, Cailin, Hu, Bing, Giles-Komar, Jill, Yang, Jing
Published in Biochemical journal (01.05.2005)
Published in Biochemical journal (01.05.2005)
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Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody
Van Kolen, Kristof, Malia, Thomas J, Theunis, Clara, Nanjunda, Rupesh, Teplyakov, Alexey, Ernst, Robin, Wu, Sheng-Jiun, Luo, Jinquan, Borgers, Marianne, Vandermeeren, Marc, Bottelbergs, Astrid, Wintmolders, Cindy, Lacy, Eilyn, Maurin, Hervé, Larsen, Peter, Willems, Roland, Van De Casteele, Tom, Triana-Baltzer, Gallen, Slemmon, Randy, Galpern, Wendy, Trojanowski, John Q, Sun, Hong, Mercken, Marc H
Published in Journal of Alzheimer's disease (01.01.2020)
Published in Journal of Alzheimer's disease (01.01.2020)
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Structure-based engineering of a monoclonal antibody for improved solubility
Wu, Sheng-Jiun, Luo, Jinquan, O'Neil, Karyn T., Kang, James, Lacy, Eilyn R., Canziani, Gabriela, Baker, Audrey, Huang, Maggie, Tang, Qing Mike, Raju, T.Shantha, Jacobs, Steven A., Teplyakov, Alexey, Gilliland, Gary L., Feng, Yiqing
Published in Protein engineering, design and selection (01.08.2010)
Published in Protein engineering, design and selection (01.08.2010)
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A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia
Nair-Gupta, Priyanka, Diem, Michael, Reeves, Dara, Wang, Weirong, Schulingkamp, Robert, Sproesser, Katrin, Mattson, Bethany, Heidrich, Bradley, Mendonça, Mark, Joseph, Jocelin, Sendecki, Jocelyn, Foulk, Brad, Chu, Gerald, Fink, Damien, Jiao, Qun, Wu, Sheng-Jiun, Packman, Kathryn, Elsayed, Yusri, Attar, Ricardo, Gaudet, François
Published in Blood advances (10.03.2020)
Published in Blood advances (10.03.2020)
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Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines
Fursov, Natalie, Lu, Jin, Healy, Catherine, Wu, Sheng-Jiun, Lacy, Eilyn, Filer, Angela, Li, Yawei, Liu, Changbao, Lamb, Roberta, Jones, Brian, Reddy, Ramachandra, Petley, Ted, Duffy, Karen
Published in Molecular immunology (01.07.2016)
Published in Molecular immunology (01.07.2016)
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Epitope Mapping of Anti-Interleukin-13 Neutralizing Antibody CNTO607
Teplyakov, Alexey, Obmolova, Galina, Wu, Sheng-Jiun, Luo, Jinquan, Kang, James, O'Neil, Karyn, Gilliland, Gary L.
Published in Journal of molecular biology (29.05.2009)
Published in Journal of molecular biology (29.05.2009)
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CCL22-specific Antibodies Reveal That Engagement of Two Distinct Binding Domains on CCL22 Is Required for CCR4-mediated Function
Santulli-Marotto, Sandra, Wheeler, John, Lacy, Eilyn R., Boakye, Ken, Luongo, Jennifer, Wu, Sheng-Jiun, Ryan, Mary
Published in Monoclonal antibodies in immunodiagnosis and immunotherapy (01.12.2015)
Published in Monoclonal antibodies in immunodiagnosis and immunotherapy (01.12.2015)
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Neutralizing monoclonal antibodies can potentiate IL‐5 signaling
Zabeau, Lennart, Van der Heyden, José, Broekaert, Daniël, Verhee, Annick, Vandekerckhove, Joël, Wu, Sheng‐Jiun, Chaiken, Irwin, Heinrich, Peter, Behrmann, Iris, Tavernier, Jan
Published in European journal of immunology (01.04.2001)
Published in European journal of immunology (01.04.2001)
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Epitope Randomization Redefines the Functional Role of Glutamic Acid 110 in Interleukin-5 Receptor Activation
Wu, Sheng-Jiun, Tambyraja, Rabindra, Zhang, Wentao, Zahn, Stefan, Godillot, A.Paul, Chaiken, Irwin
Published in The Journal of biological chemistry (10.03.2000)
Published in The Journal of biological chemistry (10.03.2000)
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