Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome
Consugar, Mark B., Wong, Wai C., Lundquist, Patrick A., Rossetti, Sandro, Kubly, Vickie J., Walker, Denise L., Rangel, Laureano J., Aspinwall, Richard, Niaudet, W. Patrick, Özen, Seza, David, Albert, Velinov, Milen, Bergstralh, Eric J., Bae, Kyongtae T., Chapman, Arlene B., Guay-Woodford, Lisa M., Grantham, Jared J., Torres, Vicente E., Sampson, Julian R., Dawson, Brian D., Harris, Peter C., for the CRISP Consortium
Published in Kidney international (01.12.2008)
Published in Kidney international (01.12.2008)
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In vitro SAR of (5-(2 H)-isoxazolonyl) ureas, potent inhibitors of hormone-sensitive lipase
Lowe, Derek B., Magnuson, Steven, Qi, Ning, Campbell, Ann-Marie, Cook, James, Hong, Zhenqiu, Wang, Ming, Rodriguez, Mareli, Achebe, Furahi, Kluender, Harold, Wong, Wai C., Bullock, William H., Salhanick, Arthur I., Witman-Jones, Terri, Bowling, Mary E., Keiper, Christine, Clairmont, Kevin B.
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
Published in Bioorganic & medicinal chemistry letters (21.06.2004)
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Arylphthalazines. Part 2: 1-(Isoquinolin-5-yl)-4-arylamino phthalazines as potent inhibitors of VEGF receptors I and II
Duncton, Matthew A.J., Piatnitski, Evgueni L., Katoch-Rouse, Reeti, Smith, Leon M., Kiselyov, Alexander S., Milligan, Daniel L., Balagtas, Chris, Wong, Wai C., Kawakami, Joel, Doody, Jacqueline F.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Discovery of Lu AA33810: A highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder
Packiarajan, Mathivanan, Marzabadi, Mohammad R., Desai, Mahesh, Lu, Yalei, Noble, Stewart A., Wong, Wai C., Jubian, Vrej, Chandrasena, Gamini, Wolinsky, Toni D., Zhong, Hualing, Walker, Mary W., Wiborg, Ove, Andersen, Kim
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Journal Article
Arylphthalazines as potent, and orally bioavailable inhibitors of VEGFR-2
Duncton, Matthew A.J., Piatnitski Chekler, Eugene L., Katoch-Rouse, Reeti, Sherman, Dan, Wong, Wai C., Smith, Leon M., Kawakami, Joel K., Kiselyov, Alexander S., Milligan, Daniel L., Balagtas, Chris, Hadari, Yaron R., Wang, Ying, Patel, Sheetal N., Rolster, Robin L., Tonra, James R., Surguladze, David, Mitelman, Stan, Kussie, Paul, Bohlen, Peter, Doody, Jacqueline F.
Published in Bioorganic & medicinal chemistry (15.01.2009)
Published in Bioorganic & medicinal chemistry (15.01.2009)
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1-[4-(1 H-Benzoimidazol-2-yl)-phenyl]-3-[4-(1 H-benzoimidazol-2-yl)-phenyl]-urea derivatives as small molecule heparanase inhibitors
Pan, Weitao, Miao, Hua-Quan, Xu, Yong-Jiang, Navarro, Elizabeth C., Tonra, James R., Corcoran, Erik, Lahiji, Armin, Kussie, Paul, Kiselyov, Alexander S., Wong, Wai C., Liu, Hu
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
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Synthesis and structure–activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors
Ouyang, Xiaohu, Chen, Xiaoling, Piatnitski, Evgueni L., Kiselyov, Alexander S., He, Hai-Ying, Mao, Yunyu, Pattaropong, Vatee, Yu, Yang, Kim, Ki H., Kincaid, John, Smith, Leon, Wong, Wai C., Lee, Sui Ping, Milligan, Daniel L., Malikzay, Asra, Fleming, James, Gerlak, Jason, Deevi, Dhanvanthri, Doody, Jacqueline F., Chiang, Hui-Hsien, Patel, Sheetal N., Wang, Ying, Rolser, Robin L., Kussie, Paul, Labelle, Marc, Tuma, M. Carolina
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Journal Article
Arylphthalazines: Identification of a new phthalazine chemotype as inhibitors of VEGFR kinase
Piatnitski, Evgueni L., Duncton, Matthew A.J., Kiselyov, Alexander S., Katoch-Rouse, Reeti, Sherman, Dan, Milligan, Daniel L., Balagtas, Chris, Wong, Wai C., Kawakami, Joel, Doody, Jacqueline F.
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Journal Article
N-(4-{[4-(1 H-Benzoimidazol-2-yl)-arylamino]-methyl}-phenyl)-benzamide derivatives as small molecule heparanase inhibitors
Xu, Yong-Jiang, Miao, Hua-Quan, Pan, Weitao, Navarro, Elizabeth C., Tonra, James R., Mitelman, Stan, Camara, M. Margarita, Deevi, Dhanvanthri S., Kiselyov, Alexander S., Kussie, Paul, Wong, Wai C., Liu, Hu
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
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Journal Article
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5- b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase
Smith, Leon, Wong, Wai C., Kiselyov, Alexander S., Burdzovic-Wizemann, Sabina, Mao, Yunyu, Xu, Yongjiang, Duncton, Matthew A.J., Kim, Ki, Piatnitski, Evgueni L., Doody, Jacqueline F., Wang, Ying, Rosler, Robin L., Milligan, Daniel, Columbus, John, Balagtas, Chris, Lee, Sui Ping, Konovalov, Andrey, Hadari, Yaron R.
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
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Preparation of Substituted Pyrimido[4,5-b]-1,4-benzoxazepines, Thiazepines, and Diazepines via a Pictet−Spengler Cyclization
Duncton, Matthew A. J, Smith, Leon M, Burdzovic-Wizeman, Sabina, Burns, Aaron, Liu, Hu, Mao, Yunyu, Wong, Wai C, Kiselyov, Alexander S
Published in Journal of organic chemistry (11.11.2005)
Published in Journal of organic chemistry (11.11.2005)
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Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases
Pan, Weitao, Liu, Hu, Xu, Yong-Jiang, Chen, Xin, Kim, Ki Hwan, Milligan, Daniel L., Columbus, John, Hadari, Yaron R., Kussie, Paul, Wong, Wai C., Labelle, Marc
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
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Design and Synthesis of Novel α1a Adrenoceptor-Selective Dihydropyridine Antagonists for the Treatment of Benign Prostatic Hyperplasia
Nagarathnam, Dhanapalan, Wetzel, John M, Miao, Shou Wu, Marzabadi, Mohammad R, Chiu, George, Wong, Wai C, Hong, Xingfang, Fang, James, Forray, Carlos, Branchek, Theresa A, Heydorn, William E, Chang, Raymond S. L, Broten, Theodore, Schorn, Terry W, Gluchowski, Charles
Published in Journal of medicinal chemistry (17.12.1998)
Published in Journal of medicinal chemistry (17.12.1998)
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Journal Article
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors
Smith, Leon, Piatnitski, Evgueni L., Kiselyov, Alexander S., Ouyang, Xiaohu, Chen, Xiaoling, Burdzovic-Wizemann, Sabina, Xu, Yongjiang, Wang, Ying, Rosler, Robin L., Patel, Sheetal N., Chiang, Hui-Hsien, Milligan, Daniel L., Columbus, John, Wong, Wai C., Doody, Jacqueline F., Hadari, Yaron R.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
2-Amino-2-oxazolines as Subtype Selective α2 Adrenoceptor Agonists
Wong, Wai C, Sun, Wanying, Cui, Weili, Chen, Yuewen, Forray, Carlos, Vaysse, Pierre J.-J, Branchek, Theresa A, Gluchowski, Charles
Published in Journal of medicinal chemistry (04.05.2000)
Published in Journal of medicinal chemistry (04.05.2000)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 3. Approaches To Eliminate Opioid Agonist Metabolites by Using Substituted Phenylpiperazine Side Chains
Lagu, Bharat, Tian, Dake, Nagarathnam, Dhanapalan, Marzabadi, Mohammad R, Wong, Wai C, Miao, Shou W, Zhang, Fengqi, Sun, Wanying, Chiu, George, Fang, James, Forray, Carlos, Chang, Raymond S. L, Ransom, Richard W, Chen, Tsing B, O'Malley, Stacey, Zhang, Kanyin, Vyas, Kamlesh P, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 4. Structure−Activity Relationship in the Dihydropyrimidine Series
Wong, Wai C, Sun, Wanying, Lagu, Bharat, Tian, Dake, Marzabadi, Mohammad R, Zhang, Fengqi, Nagarathnam, Dhanapalan, Miao, Shou W, Wetzel, John M, Peng, Jian, Forray, Carlos, Chang, Raymond S. L, Chen, Tsing B, Ransom, Richard, O'Malley, Stacey, Broten, Theodore P, Kling, Paul, Vyas, Kamlesh P, Zhang, Kanyin, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 2. Approaches To Eliminate Opioid Agonist Metabolites via Modification of Linker and 4-Methoxycarbonyl-4-phenylpiperidine Moiety
Murali Dhar, T. G, Nagarathnam, Dhanapalan, Marzabadi, Mohammad R, Lagu, Bharat, Wong, Wai C, Chiu, George, Tyagarajan, Sriram, Miao, Shou Wu, Zhang, Fengqi, Sun, Wanying, Tian, Dake, Shen, Quanrong, Zhang, Jack, Wetzel, John M, Forray, Carlos, Chang, Raymond S. L, Broten, Theodore P, Schorn, Terry W, Chen, Tsing Bao, O'Malley, Stacy, Ransom, Richard, Schneck, Kathryn, Bendesky, Robert, Harrell, Charles M, Vyas, Kamlesh P, Zhang, Kanyin, Gilbert, John, Pettibone, Douglas J, Patane, Michael A, Bock, Mark G, Freidinger, Roger M, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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Journal Article
Design and Synthesis of Novel α1 a Adrenoceptor-Selective Antagonists. 1. Structure−Activity Relationship in Dihydropyrimidinones
Nagarathnam, Dhanapalan, Miao, Shou Wu, Lagu, Bharat, Chiu, George, Fang, James, Murali Dhar, T. G, Zhang, Jack, Tyagarajan, Sriram, Marzabadi, Mohammad R, Zhang, Fengqi, Wong, Wai C, Sun, Wanying, Tian, Dake, Wetzel, John M, Forray, Carlos, Chang, Raymond S. L, Broten, Theodore P, Ransom, Richard W, Schorn, Terry W, Chen, Tsing B, O'Malley, Stacey, Kling, Paul, Schneck, Kathryn, Bendesky, Robert, Harrell, Charles M, Vyas, Kamlesh P, Gluchowski, Charles
Published in Journal of medicinal chemistry (18.11.1999)
Published in Journal of medicinal chemistry (18.11.1999)
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