Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
Magnaghi, Paola, D'Alessio, Roberto, Valsasina, Barbara, Avanzi, Nilla, Rizzi, Simona, Asa, Daniela, Gasparri, Fabio, Cozzi, Liviana, Cucchi, Ulisse, Orrenius, Christian, Polucci, Paolo, Ballinari, Dario, Perrera, Claudia, Leone, Antonella, Cervi, Giovanni, Casale, Elena, Xiao, Yang, Wong, Chihunt, Anderson, Daniel J, Galvani, Arturo, Donati, Daniele, O'Brien, Tom, Jackson, Peter K, Isacchi, Antonella
Published in Nature chemical biology (01.09.2013)
Published in Nature chemical biology (01.09.2013)
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Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis
Boyle, Monica, Wong, Chihunt, Rocha, Michael, Jones, D Leanne
Published in Cell stem cell (11.10.2007)
Published in Cell stem cell (11.10.2007)
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Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index
Desnoyers, Luc R, Vasiljeva, Olga, Richardson, Jennifer H, Yang, Annie, Menendez, Elizabeth E M, Liang, Tony W, Wong, Chihunt, Bessette, Paul H, Kamath, Kathy, Moore, Stephen J, Sagert, Jason G, Hostetter, Daniel R, Han, Fei, Gee, Jason, Flandez, Jeanne, Markham, Kate, Nguyen, Margaret, Krimm, Michael, Wong, Kenneth R, Liu, Shouchun, Daugherty, Patrick S, West, James W, Lowman, Henry B
Published in Science translational medicine (16.10.2013)
Published in Science translational medicine (16.10.2013)
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P946: TOCILIZUMAB PRE‐TREATMENT SIGNIFICANTLY REDUCES THE INCIDENCE OF CYTOKINE RELEASE SYNDROME IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA (RRMM) WHO RECEIVE CEVOSTAMAB
Mateos, Maria‐Victoria, Bahlis, Nizar J, Spencer, Andrew, Kaedbey, Rayan, Rodríguez‐Otero, Paula, Harrison, Simon, Wong, Chihunt, Goodman, Grant, Nakamura, Rin, Choeurng, Voleak, Cooper, James, Trudel, Suzanne
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Stem Cell Dynamics in Response to Nutrient Availability
McLeod, Catherine J., Wang, Lei, Wong, Chihunt, Jones, D. Leanne
Published in Current biology (07.12.2010)
Published in Current biology (07.12.2010)
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Pretreatment with Tocilizumab Prior to the CD3 Bispecific Cevostamab in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Showed a Marked Reduction in Cytokine Release Syndrome Incidence and Severity
Trudel, Suzanne, Bahlis, Nizar J., Spencer, Andrew, Kaedbey, Rayan, Rodriguez Otero, Paula, Harrison, Simon J, Wong, Chihunt, Goodman, Grant R., Nakamura, Rin, Choeurng, Voleak, Cooper, James, Mateos, Maria-Victoria
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells
Mérino, Delphine, Khaw, Seong L., Glaser, Stefan P., Anderson, Daniel J., Belmont, Lisa D., Wong, Chihunt, Yue, Peng, Robati, Mikara, Phipson, Belinda, Fairlie, Walter D., Lee, Erinna F., Campbell, Kirsteen J., Vandenberg, Cassandra J., Cory, Suzanne, Roberts, Andrew W., Ludlam, Mary J.C., Huang, David C.S., Bouillet, Philippe
Published in Blood (14.06.2012)
Published in Blood (14.06.2012)
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Enduring Responses after 1-Year, Fixed-Duration Cevostamab Therapy in Patients with Relapsed/Refractory Multiple Myeloma: Early Experience from a Phase I Study
Lesokhin, Alexander M, Richter, Joshua, Trudel, Suzanne, Cohen, Adam D, Spencer, Andrew, Forsberg, Peter A, Laubach, Jacob P, Thomas, Sheeba K, Bahlis, Nizar J., Costa, Luciano J., Rodriguez Otero, Paula, Mateos, Maria-Victoria, Berdeja, Jesus G, Kaedbey, Rayan, Krishnan, Amrita Y., Fonseca, Rafael, Choeurng, Voleak, Cooper, James, Sumiyoshi, Teiko, Wong, Chihunt, Harrison, Simon J
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Cevostamab Monotherapy Continues to Show Clinically Meaningful Activity and Manageable Safety in Patients with Heavily Pre-Treated Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from an Ongoing Phase I Study
Trudel, Suzanne, Cohen, Adam D, Krishnan, Amrita Y., Fonseca, Rafael, Spencer, Andrew, Berdeja, Jesús G., Lesokhin, Alexander, Forsberg, Peter A, Laubach, Jacob P., Costa, Luciano J., Rodriguez-Otero, Paula, Kaedbey, Rayan, Richter, Joshua, Mateos, Maria-Victoria, Thomas, Sheeba K, Wong, Chihunt, Li, Mengsong, Choeurng, Voleak, Vaze, Anjali, Samineni, Divya, Sumiyoshi, Teiko, Cooper, James, Harrison, Simon J
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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P-012: Cevostamab is efficacious and well tolerated in patients aged < 65 and ≥65 years with relapsed/refractory multiple myeloma (RRMM)
Krishnan, Amrita, Cohen, Adam, Trudel, Suzanne, Spencer, Andrew, Lesokhin, Alexander, Wong, Chihunt, Choeurng, Voleak, Cooper, James, Sumiyoshi, Teiko, Goodman, Grant, Jin, Hyun Yong, Sheikh, Semira, Harrison, Simon
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
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Preliminary single-dose clinical pharmacokinetics of an anti–PD-L1 Probody therapeutic (Pb-Tx) in cancer patients
Stroh, Mark, Serwer, Laura, Lu, Hong, Huels, Vanessa, Wong, Chihunt, Zheng, Beiyao, Millard, Bjorn L., Apgar, Joshua F., Zheng, Nancy, Richardson, Jennifer Hope, Will, Matthias, Humphrey, Rachel W.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents
Assi, Hikmat H, Wong, Chihunt, Tipton, Kimberly A, Mei, Li, Wong, Ken, Razo, Jennifer, Chan, Chanty, Howng, Bruce, Sagert, Jason, Krimm, Michael, Diep, Linnea, Jang, Andrew, Nguyen, Margaret T, Lapuyade, Nicole, Singson, Victoria, Villanueva, Ruth, Paidhungat, Madan, Liu, Shouchun, Rangan, Vangipuram, Vasiljeva, Olga, West, James W, Richardson, Jennifer H, Irving, Bryan, Daniel, Dylan, Belvin, Marcia, Kavanaugh, W Michael
Published in Cancer immunology research (01.12.2021)
Published in Cancer immunology research (01.12.2021)
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PROCLAIM-001: A first-in-human trial to assess tolerability of the protease-activatable anti-PD-L1 Probody CX-072 in solid tumors and lymphomas
Spira, Alexander I., Middleton, Mark R., Naing, Aung, Autio, Karen A., Nemunaitis, John J., Bendell, Johanna C., Gordon, Michael, Humphrey, Rachel W., Wong, Chihunt, Rizvi, Naiyer A.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Abstract 2665: Transforming Notch ligands into tumor-antigen targets: A Probody-Drug Conjugate (PDC) targeting Jagged 1 and Jagged 2
Sagert, Jason, West, Jim, Wong, Chihunt, Desnoyers, Luc, Vasiljeva, Olga, Richardson, Jennifer, Polu, Krishna, Lowman, Henry
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract C158: Tumor-specific inhibition of jagged-dependent notch signaling using a Probody™ therapeutic
Sagert, Jason, West, James, Vasiljeva, Olga, Richardson, Jennifer, Desnoyers, Luc, Liu, Shouchun, Yang, Annie, Wong, Chihunt, Menendez, Elizabeth, Polu, Krishna, Lowman, Henry
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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HIM-8 binds to the X chromosome pairing center and mediateschromosome-specific meiotic synapsis
Phillips, Carolyn M., Wong, Chihunt, Bhalla, Needhi, Carlton,Peter M., Weiser, Pinky, Meneely, Philip M., Dernburg, Abby F.
Published in Cell (05.06.2005)
Published in Cell (05.06.2005)
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