Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice
Zhan, Wenhu, Zhang, Hao, Ginn, John, Leung, Annie, Liu, Yi J., Michino, Mayako, Toita, Akinori, Okamoto, Rei, Wong, Tzu‐Tshin, Imaeda, Toshihiro, Hara, Ryoma, Yukawa, Takafumi, Chelebieva, Sevil, Tumwebaze, Patrick K., Lafuente‐Monasterio, Maria Jose, Martinez‐Martinez, Maria Santos, Vendome, Jeremie, Beuming, Thijs, Sato, Kenjiro, Aso, Kazuyoshi, Rosenthal, Philip J., Cooper, Roland A., Meinke, Peter T., Nathan, Carl F., Kirkman, Laura A., Lin, Gang
Published in Angewandte Chemie International Edition (19.04.2021)
Published in Angewandte Chemie International Edition (19.04.2021)
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Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors
Zhang, Hao, Ginn, John, Zhan, Wenhu, Liu, Yi J., Leung, Annie, Toita, Akinori, Okamoto, Rei, Wong, Tzu-Tshin, Imaeda, Toshihiro, Hara, Ryoma, Yukawa, Takafumi, Michino, Mayako, Vendome, Jeremie, Beuming, Thijs, Sato, Kenjiro, Aso, Kazuyoshi, Meinke, Peter T., Nathan, Carl F., Kirkman, Laura A., Lin, Gang
Published in Journal of medicinal chemistry (14.07.2022)
Published in Journal of medicinal chemistry (14.07.2022)
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Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome
Zhang, Hao, Hsu, Hao-Chi, Kahne, Shoshanna C, Hara, Ryoma, Zhan, Wenhu, Jiang, Xiuju, Burns-Huang, Kristin, Ouellette, Tierra, Imaeda, Toshihiro, Okamoto, Rei, Kawasaki, Masanori, Michino, Mayako, Wong, Tzu-Tshin, Toita, Akinori, Yukawa, Takafumi, Moraca, Francesca, Vendome, Jeremie, Saha, Priya, Sato, Kenjiro, Aso, Kazuyoshi, Ginn, John, Meinke, Peter T, Foley, Michael, Nathan, Carl F, Darwin, K. Heran, Li, Huilin, Lin, Gang
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors
Zhan, Wenhu, Visone, Joseph, Ouellette, Tierra, Harris, Jacob C, Wang, Rong, Zhang, Hao, Singh, Pradeep K, Ginn, John, Sukenick, George, Wong, Tzu-Tshin, Okoro, Judith I, Scales, Ryan M, Tumwebaze, Patrick K, Rosenthal, Philip J, Kafsack, Björn F. C, Cooper, Roland A, Meinke, Peter T, Kirkman, Laura A, Lin, Gang
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Structure–Activity Relationship Studies of Antimalarial Plasmodium Proteasome InhibitorsPart II
Zhang, Hao, Ginn, John, Zhan, Wenhu, Leung, Annie, Liu, Yi J., Toita, Akinori, Okamoto, Rei, Wong, Tzu-Tshin, Imaeda, Toshihiro, Hara, Ryoma, Michino, Mayako, Yukawa, Takafumi, Chelebieva, Sevil, Tumwebaze, Patrick K., Vendome, Jeremie, Beuming, Thijs, Sato, Kenjiro, Aso, Kazuyoshi, Rosenthal, Philip J., Cooper, Roland A., Liverton, Nigel, Foley, Michael, Meinke, Peter T., Nathan, Carl F., Kirkman, Laura A., Lin, Gang
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents
Kojima, Takuto, Asano, Yasutomi, Kurasawa, Osamu, Hirata, Yasuhiro, Iwamura, Naoki, Wong, Tzu-Tshin, Saito, Bunnai, Tanaka, Yuta, Arai, Ryosuke, Yonemori, Kazuko, Miyamoto, Yasufumi, Sagiya, Yoji, Yaguchi, Masahiro, Shibata, Sachio, Mizutani, Akio, Sano, Osamu, Adachi, Ryutaro, Satomi, Yoshinori, Hirayama, Megumi, Aoyama, Kazunobu, Hiura, Yuto, Kiba, Atsushi, Kitamura, Shuji, Imamura, Shinichi
Published in Bioorganic & medicinal chemistry (15.05.2018)
Published in Bioorganic & medicinal chemistry (15.05.2018)
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Journal Article
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice
Zhan, Wenhu, Zhang, Hao, Ginn, John, Leung, Annie, Liu, Yi J., Michino, Mayako, Toita, Akinori, Okamoto, Rei, Wong, Tzu‐Tshin, Imaeda, Toshihiro, Hara, Ryoma, Yukawa, Takafumi, Chelebieva, Sevil, Tumwebaze, Patrick K., Lafuente‐Monasterio, Maria Jose, Martinez‐Martinez, Maria Santos, Vendome, Jeremie, Beuming, Thijs, Sato, Kenjiro, Aso, Kazuyoshi, Rosenthal, Philip J., Cooper, Roland A., Meinke, Peter T., Nathan, Carl F., Kirkman, Laura A., Lin, Gang
Published in Angewandte Chemie (19.04.2021)
Published in Angewandte Chemie (19.04.2021)
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Year of Publication 27.10.2016
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Year of Publication 22.08.2023
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ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE
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Year of Publication 04.07.2023
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Year of Publication 24.02.2022
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MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS
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Year of Publication 13.10.2022
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Year of Publication 27.10.2021
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Year of Publication 27.10.2021
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HETEROARYLS AND USES THEREOF
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Year of Publication 04.04.2023
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