An open source automated tumor infiltrating lymphocyte algorithm for prognosis in melanoma
Acs, Balazs, Ahmed, Fahad Shabbir, Gupta, Swati, Wong, Pok Fai, Gartrell, Robyn D., Sarin Pradhan, Jaya, Rizk, Emanuelle M., Gould Rothberg, Bonnie, Saenger, Yvonne M., Rimm, David L.
Published in Nature communications (29.11.2019)
Published in Nature communications (29.11.2019)
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Journal Article
High-Plex Predictive Marker Discovery for Melanoma Immunotherapy-Treated Patients Using Digital Spatial Profiling
Toki, Maria I, Merritt, Christopher R, Wong, Pok Fai, Smithy, James W, Kluger, Harriet M, Syrigos, Konstantinos N, Ong, Giang T, Warren, Sarah E, Beechem, Joseph M, Rimm, David L
Published in Clinical cancer research (15.09.2019)
Published in Clinical cancer research (15.09.2019)
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Journal Article
Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma
Wong, Pok Fai, Wei, Wei, Smithy, James W, Acs, Balazs, Toki, Maria I, Blenman, Kim R M, Zelterman, Daniel, Kluger, Harriet M, Rimm, David L
Published in Clinical cancer research (15.04.2019)
Published in Clinical cancer research (15.04.2019)
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Journal Article
Deep Learning Based on Standard H&E Images of Primary Melanoma Tumors Identifies Patients at Risk for Visceral Recurrence and Death
Kulkarni, Prathamesh M, Robinson, Eric J, Sarin Pradhan, Jaya, Gartrell-Corrado, Robyn D, Rohr, Bethany R, Trager, Megan H, Geskin, Larisa J, Kluger, Harriet M, Wong, Pok Fai, Acs, Balazs, Rizk, Emanuelle M, Yang, Chen, Mondal, Manas, Moore, Michael R, Osman, Iman, Phelps, Robert, Horst, Basil A, Chen, Zhe S, Ferringer, Tammie, Rimm, David L, Wang, Jing, Saenger, Yvonne M
Published in Clinical cancer research (01.03.2020)
Published in Clinical cancer research (01.03.2020)
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Journal Article
Quantitative analysis of CMTM6 expression in tumor microenvironment in metastatic melanoma and association with outcome on immunotherapy
Martinez-Morilla, Sandra, Zugazagoitia, Jon, Wong, Pok Fai, Kluger, Harriet M., Rimm, David L.
Published in Oncoimmunology (01.01.2021)
Published in Oncoimmunology (01.01.2021)
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Journal Article
Biotransformations of Anticancer Ruthenium(III) Complexes: An X-Ray Absorption Spectroscopic Study
Levina, Aviva, Aitken, Jade B., Gwee, Yee Yen, Lim, Zhi Jun, Liu, Mimi, Singharay, Anannya Mitra, Wong, Pok Fai, Lay, Peter A.
Published in Chemistry : a European journal (11.03.2013)
Published in Chemistry : a European journal (11.03.2013)
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Journal Article
Digital spatial profiling of melanoma shows CD95 expression in immune cells is associated with resistance to immunotherapy
Martinez-Morilla, Sandra, Moutafi, Myrto, Fernandez, Aileen I., Jessel, Shlomit, Divakar, Prajan, Wong, Pok Fai, Garcia-Milian, Rolando, Schalper, Kurt A., Kluger, Harriet M., Rimm, David L.
Published in Oncoimmunology (31.12.2023)
Published in Oncoimmunology (31.12.2023)
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Journal Article
Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy outcome in metastatic melanoma
Wong, Pok Fai, Wei, Wei, Gupta, Swati, Smithy, James W, Zelterman, Daniel, Kluger, Harriet M, Rimm, David L
Published in Journal for immunotherapy of cancer (23.07.2019)
Published in Journal for immunotherapy of cancer (23.07.2019)
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Journal Article
Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality
Vathiotis, Ioannis A., Yang, Zhi, Reeves, Jason, Toki, Maria, Aung, Thazin Nwe, Wong, Pok Fai, Kluger, Harriet, Syrigos, Konstantinos N., Warren, Sarah, Rimm, David L.
Published in NPJ precision oncology (28.05.2021)
Published in NPJ precision oncology (28.05.2021)
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Journal Article
Nuclear IRF-1 expression as a mechanism to assess "Capability" to express PD-L1 and response to PD-1 therapy in metastatic melanoma
Smithy, James W, Moore, Lauren M, Pelekanou, Vasiliki, Rehman, Jamaal, Gaule, Patricia, Wong, Pok Fai, Neumeister, Veronique M, Sznol, Mario, Kluger, Harriet M, Rimm, David L
Published in Journal for immunotherapy of cancer (21.03.2017)
Published in Journal for immunotherapy of cancer (21.03.2017)
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Journal Article
Baseline gene expression profiling determines long-term benefit to programmed cell death protein 1 axis blockade
Vathiotis, Ioannis A., Salichos, Leonidas, Martinez-Morilla, Sandra, Gavrielatou, Niki, Aung, Thazin Nwe, Shafi, Saba, Wong, Pok Fai, Jessel, Shlomit, Kluger, Harriet M., Syrigos, Konstantinos N., Warren, Sarah, Gerstein, Mark, Rimm, David L.
Published in NPJ precision oncology (15.12.2022)
Published in NPJ precision oncology (15.12.2022)
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Journal Article
Closed system RT-qPCR as a potential companion diagnostic test for immunotherapy outcome in metastatic melanoma
Gupta, Swati, McCann, Leena, Chan, Yvonne G. Y., Lai, Edwin W., Wei, Wei, Wong, Pok Fai, Smithy, James W., Weidler, Jodi, Rhees, Brian, Bates, Michael, Kluger, Harriet M., Rimm, David L.
Published in Journal for immunotherapy of cancer (18.09.2019)
Published in Journal for immunotherapy of cancer (18.09.2019)
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Journal Article
Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling
Wu, Jinfeng, Xu, Hailin, Wong, Pok Fai, Xia, Shijin, Xu, Jinhua, Dong, Jingcheng
Published in Food and chemical toxicology (01.02.2014)
Published in Food and chemical toxicology (01.02.2014)
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Journal Article
Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade
Berry, Sneha, Giraldo, Nicolas A, Green, Benjamin F, Cottrell, Tricia R, Stein, Julie E, Engle, Elizabeth L, Xu, Haiying, Ogurtsova, Aleksandra, Roberts, Charles, Wang, Daphne, Nguyen, Peter, Zhu, Qingfeng, Soto-Diaz, Sigfredo, Loyola, Jose, Sander, Inbal B, Wong, Pok Fai, Jessel, Shlomit, Doyle, Joshua, Signer, Danielle, Wilton, Richard, Roskes, Jeffrey S, Eminizer, Margaret, Park, Seyoun, Sunshine, Joel C, Jaffee, Elizabeth M, Baras, Alexander, De Marzo, Angelo M, Topalian, Suzanne L, Kluger, Harriet, Cope, Leslie, Lipson, Evan J, Danilova, Ludmila, Anders, Robert A, Rimm, David L, Pardoll, Drew M, Szalay, Alexander S, Taube, Janis M
Published in Science (American Association for the Advancement of Science) (11.06.2021)
Published in Science (American Association for the Advancement of Science) (11.06.2021)
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Journal Article
Biomarker Discovery in Patients with Immunotherapy-Treated Melanoma with Imaging Mass Cytometry
Martinez-Morilla, Sandra, Villarroel-Espindola, Franz, Wong, Pok Fai, Toki, Maria I, Aung, Thazin Nwe, Pelekanou, Vasiliki, Bourke-Martin, Brian, Schalper, Kurt A, Kluger, Harriet M, Rimm, David L
Published in Clinical cancer research (01.04.2021)
Published in Clinical cancer research (01.04.2021)
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Journal Article
Clinical-Grade Validation of an Autofluorescence Virtual Staining System With Human Experts and a Deep Learning System for Prostate Cancer
Wong, Pok Fai, McNeil, Carson, Wang, Yang, Paparian, Jack, Santori, Charles, Gutierrez, Michael, Homyk, Andrew, Nagpal, Kunal, Jaroensri, Tiam, Wulczyn, Ellery, Yoshitake, Tadayuki, Sigman, Julia, Steiner, David F., Rao, Sudha, Cameron Chen, Po-Hsuan, Restorick, Luke, Roy, Jonathan, Cimermancic, Peter
Published in Modern pathology (01.11.2024)
Published in Modern pathology (01.11.2024)
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Journal Article
Abstract 2001: Biomarker discovery in immunotherapy-treated melanoma patients with imaging mass cytometry
Martinez-Morilla, Sandra, Villarroel-Espindola, Franz, Wong, Pok Fai, Kluger, Harriet, Toki, Maria, Aung, Thazin New, Pelekanou, Vasiliki, Bourke-Martin, Brian, Rimm, David L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 3095: Combination of spatial protein data with bulk transcriptional profiling of the same cohort shows relationships between RNA and protein and facilitates combined predictive signatures
Vathiotis, Ioannis A., Reeves, Jason, Toki, Maria, Wong, Pok Fai, Kluger, Harriet, Aung, Thazin Nwe, Syrigos, Konstantinos N., Warren, Sarah, Rimm, David L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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