A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
Sey, Nancy Y A, Hu, Benxia, Mah, Won, Fauni, Harper, McAfee, Jessica Caitlin, Rajarajan, Prashanth, Brennand, Kristen J, Akbarian, Schahram, Won, Hyejung
Published in Nature neuroscience (01.04.2020)
Published in Nature neuroscience (01.04.2020)
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Journal Article
Advancing the understanding of autism disease mechanisms through genetics
de la Torre-Ubieta, Luis, Won, Hyejung, Stein, Jason L, Geschwind, Daniel H
Published in Nature medicine (01.04.2016)
Published in Nature medicine (01.04.2016)
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Journal Article
The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
de la Torre-Ubieta, Luis, Stein, Jason L., Won, Hyejung, Opland, Carli K., Liang, Dan, Lu, Daning, Geschwind, Daniel H.
Published in Cell (11.01.2018)
Published in Cell (11.01.2018)
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Journal Article
Chromosome conformation elucidates regulatory relationships in developing human brain
Won, Hyejung, de la Torre-Ubieta, Luis, Stein, Jason L, Parikshak, Neelroop N, Huang, Jerry, Opland, Carli K, Gandal, Michael J, Sutton, Gavin J, Hormozdiari, Farhad, Lu, Daning, Lee, Changhoon, Eskin, Eleazar, Voineagu, Irina, Ernst, Jason, Geschwind, Daniel H
Published in Nature (London) (27.10.2016)
Published in Nature (London) (27.10.2016)
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Journal Article
De novo mutations in regulatory elements in neurodevelopmental disorders
Short, Patrick J, McRae, Jeremy F, Gallone, Giuseppe, Sifrim, Alejandro, Won, Hyejung, Geschwind, Daniel H, Wright, Caroline F, Firth, Helen V, FitzPatrick, David R, Barrett, Jeffrey C, Hurles, Matthew E
Published in Nature (London) (29.03.2018)
Published in Nature (London) (29.03.2018)
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Journal Article
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
Ramaswami, Gokul, Won, Hyejung, Gandal, Michael J., Haney, Jillian, Wang, Jerry C., Wong, Chloe C. Y., Sun, Wenjie, Prabhakar, Shyam, Mill, Jonathan, Geschwind, Daniel H.
Published in Nature communications (25.09.2020)
Published in Nature communications (25.09.2020)
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Journal Article
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Gusev, Alexander, Mancuso, Nicholas, Won, Hyejung, Kousi, Maria, Finucane, Hilary K, Reshef, Yakir, Song, Lingyun, Safi, Alexias, McCarroll, Steven, Neale, Benjamin M, Ophoff, Roel A, O'Donovan, Michael C, Crawford, Gregory E, Geschwind, Daniel H, Katsanis, Nicholas, Sullivan, Patrick F, Pasaniuc, Bogdan, Price, Alkes L
Published in Nature genetics (01.04.2018)
Published in Nature genetics (01.04.2018)
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Journal Article
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
Rajarajan, Prashanth, Borrman, Tyler, Liao, Will, Schrode, Nadine, Flaherty, Erin, Casiño, Charlize, Powell, Samuel, Yashaswini, Chittampalli, LaMarca, Elizabeth A, Kassim, Bibi, Javidfar, Behnam, Espeso-Gil, Sergio, Li, Aiqun, Won, Hyejung, Geschwind, Daniel H, Ho, Seok-Man, MacDonald, Matthew, Hoffman, Gabriel E, Roussos, Panos, Zhang, Bin, Hahn, Chang-Gyu, Weng, Zhiping, Brennand, Kristen J, Akbarian, Schahram
Published in Science (American Association for the Advancement of Science) (14.12.2018)
Published in Science (American Association for the Advancement of Science) (14.12.2018)
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Journal Article
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Schork, Andrew J, Won, Hyejung, Appadurai, Vivek, Nudel, Ron, Gandal, Mike, Delaneau, Olivier, Revsbech Christiansen, Malene, Hougaard, David M, Bækved-Hansen, Marie, Bybjerg-Grauholm, Jonas, Giørtz Pedersen, Marianne, Agerbo, Esben, Bøcker Pedersen, Carsten, Neale, Benjamin M, Daly, Mark J, Wray, Naomi R, Nordentoft, Merete, Mors, Ole, Børglum, Anders D, Bo Mortensen, Preben, Buil, Alfonso, Thompson, Wesley K, Geschwind, Daniel H, Werge, Thomas
Published in Nature neuroscience (01.03.2019)
Published in Nature neuroscience (01.03.2019)
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Journal Article
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
Quach, Bryan C, Bray, Michael J, Gaddis, Nathan C, Liu, Mengzhen, Palviainen, Teemu, Minica, Camelia C, Zellers, Stephanie, Sherva, Richard, Aliev, Fazil, Nothnagel, Michael, Young, Kendra A, Marks, Jesse A, Young, Hannah, Carnes, Megan U, Guo, Yuelong, Waldrop, Alex, Sey, Nancy Y A, Landi, Maria T, McNeil, Daniel W, Drichel, Dmitriy, Farrer, Lindsay A, Markunas, Christina A, Vink, Jacqueline M, Hottenga, Jouke-Jan, Iacono, William G, Kranzler, Henry R, Saccone, Nancy L, Neale, Michael C, Madden, Pamela, Rietschel, Marcella, Marazita, Mary L, McGue, Matthew, Won, Hyejung, Winterer, Georg, Grucza, Richard, Dick, Danielle M, Gelernter, Joel, Caporaso, Neil E, Baker, Timothy B, Boomsma, Dorret I, Kaprio, Jaakko, Hokanson, John E, Vrieze, Scott, Bierut, Laura J, Johnson, Eric O, Hancock, Dana B
Published in Nature communications (03.11.2020)
Published in Nature communications (03.11.2020)
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Journal Article
The genetic relationships between brain structure and schizophrenia
Stauffer, Eva-Maria, Bethlehem, Richard A. I., Dorfschmidt, Lena, Won, Hyejung, Warrier, Varun, Bullmore, Edward T.
Published in Nature communications (28.11.2023)
Published in Nature communications (28.11.2023)
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Journal Article
Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2−/− Mice
Chung, Changuk, Ha, Seungmin, Kang, Hyojin, Lee, Jiseok, Um, Seung Min, Yan, Haidun, Yoo, Ye-Eun, Yoo, Taesun, Jung, Hwajin, Lee, Dongwon, Lee, Eunee, Lee, Seungjoon, Kim, Jihye, Kim, Ryunhee, Kwon, Yonghan, Kim, Woohyun, Kim, Hyosang, Duffney, Lara, Kim, Doyoun, Mah, Won, Won, Hyejung, Mo, Seojung, Kim, Jin Yong, Lim, Chae-Seok, Kaang, Bong-Kiun, Boeckers, Tobias M., Chung, Yeonseung, Kim, Hyun, Jiang, Yong-hui, Kim, Eunjoon
Published in Biological psychiatry (1969) (01.04.2019)
Published in Biological psychiatry (1969) (01.04.2019)
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Journal Article
Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex
Liu, Shuang, Won, Hyejung, Clarke, Declan, Matoba, Nana, Khullar, Saniya, Mu, Yudi, Wang, Daifeng, Gerstein, Mark
Published in Genome medicine (24.11.2022)
Published in Genome medicine (24.11.2022)
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Journal Article
Social and non-social autism symptoms and trait domains are genetically dissociable
Warrier, Varun, Toro, Roberto, Won, Hyejung, Leblond, Claire S, Cliquet, Freddy, Delorme, Richard, De Witte, Ward, Bralten, Janita, Chakrabarti, Bhismadev, Børglum, Anders D, Grove, Jakob, Poelmans, Geert, Hinds, David A, Bourgeron, Thomas, Baron-Cohen, Simon
Published in Communications biology (03.09.2019)
Published in Communications biology (03.09.2019)
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Journal Article
Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases
Chen, Jason A, Chen, Zhongbo, Won, Hyejung, Huang, Alden Y, Lowe, Jennifer K, Wojta, Kevin, Yokoyama, Jennifer S, Bensimon, Gilbert, Leigh, P Nigel, Payan, Christine, Shatunov, Aleksey, Jones, Ashley R, Lewis, Cathryn M, Deloukas, Panagiotis, Amouyel, Philippe, Tzourio, Christophe, Dartigues, Jean-Francois, Ludolph, Albert, Boxer, Adam L, Bronstein, Jeff M, Al-Chalabi, Ammar, Geschwind, Daniel H, Coppola, Giovanni
Published in Molecular neurodegeneration (08.08.2018)
Published in Molecular neurodegeneration (08.08.2018)
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Journal Article
Focus on your locus with a massively parallel reporter assay
McAfee, Jessica C, Bell, Jessica L, Krupa, Oleh, Matoba, Nana, Stein, Jason L, Won, Hyejung
Published in Journal of neurodevelopmental disorders (09.09.2022)
Published in Journal of neurodevelopmental disorders (09.09.2022)
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Journal Article