Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy
Niemann, Julia, Woller, Norman, Brooks, Jennifer, Fleischmann-Mundt, Bettina, Martin, Nikolas T, Kloos, Arnold, Knocke, Sarah, Ernst, Amanda M, Manns, Michael P, Kubicka, Stefan, Wirth, Thomas C, Gerardy-Schahn, Rita, Kühnel, Florian
Published in Nature communications (19.07.2019)
Published in Nature communications (19.07.2019)
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The Co‐mutational Spectrum Determines the Therapeutic Response in Murine FGFR2 Fusion‐Driven Cholangiocarcinoma
Kendre, Gajanan, Marhenke, Silke, Lorz, Georgina, Becker, Diana, Reineke‐Plaaß, Tanja, Poth, Tanja, Murugesan, Karthikeyan, Kühnel, Florian, Woller, Norman, Wirtz, Ralph M., Pich, Andreas, Marquardt, Jens U., Saborowski, Michael, Vogel, Arndt, Saborowski, Anna
Published in Hepatology (Baltimore, Md.) (01.09.2021)
Published in Hepatology (Baltimore, Md.) (01.09.2021)
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Prospects and Challenges for T Cell-Based Therapies of HCC
Woller, Norman, Engelskircher, Sophie Anna, Wirth, Thomas, Wedemeyer, Heiner
Published in Cells (Basel, Switzerland) (30.06.2021)
Published in Cells (Basel, Switzerland) (30.06.2021)
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Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing
Mishra, Amrendra, Emamgholi, Fatemeh, Erlangga, Zulrahman, Hartleben, Björn, Unger, Kristian, Wolff, Katharina, Teichmann, Ulrike, Kessel, Michael, Woller, Norman, Kühnel, Florian, Dow, Lukas E, Manns, Michael P, Vogel, Arndt, Lowe, Scott W, Saborowski, Anna, Saborowski, Michael
Published in Carcinogenesis (New York) (14.05.2020)
Published in Carcinogenesis (New York) (14.05.2020)
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Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer
Erlangga, Zulrahman, Wolff, Katharina, Poth, Tanja, Peltzer, Alexander, Nahnsen, Sven, Spielberg, Steffi, Timrott, Kai, Woller, Norman, Kühnel, Florian, Manns, Michael P, Saborowski, Anna, Vogel, Arndt, Saborowski, Michael
Published in Cancers (29.11.2019)
Published in Cancers (29.11.2019)
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PD-1/CTLA-4 Blockade Leads to Expansion of CD8+PD-1int TILs and Results in Tumor Remission in Experimental Liver Cancer
Bufe, Sandra, Zimmermann, Artur, Ravens, Sarina, Prinz, Immo, Buitrago-Molina, Laura Elisa, Geffers, Robert, Woller, Norman, Kühnel, Florian, Talbot, Steven R., Noyan, Fatih, Manns, Michael Peter, Wedemeyer, Heiner, Hardtke-Wolenski, Matthias, Jaeckel, Elmar, Davalos-Misslitz, Ana C.
Published in Liver cancer (Basel ) (01.06.2023)
Published in Liver cancer (Basel ) (01.06.2023)
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Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro
Saborowski, Anna, Wolff, Katharina, Spielberg, Steffi, Beer, Benedikt, Hartleben, Björn, Erlangga, Zulrahman, Becker, Diana, Dow, Lukas E., Marhenke, Silke, Woller, Norman, Unger, Kristian, Schirmacher, Peter, Manns, Michael P., Marquardt, Jens U., Vogel, Arndt, Saborowski, Michael
Published in Hepatology communications (01.03.2019)
Published in Hepatology communications (01.03.2019)
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Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1
Wirth, Thomas, Kühnel, Florian, Fleischmann-Mundt, Bettina, Woller, Norman, Djojosubroto, Meta, Rudolph, Karl Lenhard, Manns, Michael, Zender, Lars, Kubicka, Stefan
Published in Cancer research (Chicago, Ill.) (15.08.2005)
Published in Cancer research (Chicago, Ill.) (15.08.2005)
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CD4 and CD8 T lymphocyte interplay in controlling tumor growth
Ostroumov, Dmitrij, Fekete-Drimusz, Nora, Saborowski, Michael, Kühnel, Florian, Woller, Norman
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
Published in Cellular and molecular life sciences : CMLS (01.02.2018)
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Protein Transduction Domains Fused to Virus Receptors Improve Cellular Virus Uptake and Enhance Oncolysis by Tumor-Specific Replicating Vectors
KÜHNEL, Florian, SCHULTE, Bernd, WIRTH, Thomas, WOLLER, Norman, SCHÄFERS, Sonja, ZENDER, Lars, MANNS, Michael, KUBICKA, Stefan
Published in Journal of Virology (01.12.2004)
Published in Journal of Virology (01.12.2004)
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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
KANG, Tae-Won, YEVSA, Tetyana, IKEN, Marcus, VUCUR, Mihael, WEISS, Siegfried, HEIKENWALDER, Mathias, KHAN, Sadaf, GIL, Jesus, BRUDER, Dunja, MANNS, Michael, SCHIRMACHER, Peter, TACKE, Frank, WOLLER, Norman, OTT, Michael, LUEDDE, Tom, LONGERICH, Thomas, KUBICKA, Stefan, ZENDER, Lars, HOENICKE, Lisa, WUESTEFELD, Torsten, DAUCH, Daniel, HOHMEYER, Anja, GEREKE, Marcus, RUDALSKA, Ramona, POTAPOVA, Anna
Published in Nature (London) (24.11.2011)
Published in Nature (London) (24.11.2011)
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Transcriptome Profiling Identifies TIGIT as a Marker of T‐Cell Exhaustion in Liver Cancer
Ostroumov, Dmitrij, Duong, Steven, Wingerath, Jessica, Woller, Norman, Manns, Michael P., Timrott, Kai, Kleine, Moritz, Ramackers, Wolf, Roessler, Stephanie, Nahnsen, Sven, immunoglobulin and immunoreceptor tyrosiCzemmel, Dittrich‐Breiholz, Oliver, Eggert, Tobias, Kühnel, Florian, Wirth, Thomas C.
Published in Hepatology (Baltimore, Md.) (01.04.2021)
Published in Hepatology (Baltimore, Md.) (01.04.2021)
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Tailored Tumor Immunogenicity Reveals Regulation of CD4 and CD8 T Cell Responses against Cancer
Knocke, Sarah, Fleischmann-Mundt, Bettina, Saborowski, Michael, Manns, Michael P., Kühnel, Florian, Wirth, Thomas C., Woller, Norman
Published in Cell reports (Cambridge) (22.11.2016)
Published in Cell reports (Cambridge) (22.11.2016)
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Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer
Brooks, Jennifer, Fleischmann-Mundt, Bettina, Woller, Norman, Niemann, Julia, Ribback, Silvia, Peters, Kristin, Demir, Ihsan Ekin, Armbrecht, Nina, Ceyhan, Guralp O, Manns, Michael P, Wirth, Thomas C, Kubicka, Stefan, Bernhardt, Gunter, Smyth, Mark J, Calvisi, Diego F, Gürlevik, Engin, Kühnel, Florian
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+ T cells
Hardtke‐Wolenski, Matthias, Fischer, Katja, Noyan, Fatih, Schlue, Jerome, Falk, Christine S., Stahlhut, Maike, Woller, Norman, Kuehnel, Florian, Taubert, Richard, Manns, Michael P., Jaeckel, Elmar
Published in Hepatology (Baltimore, Md.) (01.08.2013)
Published in Hepatology (Baltimore, Md.) (01.08.2013)
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Impending HCC diagnosis in patients with cirrhosis after HCV cure features a natural killer cell signature
Engelskircher, Sophie Anna, Chen, Po-Chun, Strunz, Benedikt, Oltmanns, Carlos, Ristic, Tijana, Owusu Sekyere, Solomon, Kraft, Anke R M, Cornberg, Markus, Wirth, Thomas, Heinrich, Bernd, Björkström, Niklas K, Wedemeyer, Heiner, Woller, Norman
Published in Hepatology (Baltimore, Md.) (20.02.2024)
Published in Hepatology (Baltimore, Md.) (20.02.2024)
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Imprint of unconventional T‐cell response in acute hepatitis C persists despite successful early antiviral treatment
Du, Yanqin, Khera, Tanvi, Strunz, Benedikt, Deterding, Katja, Todt, Daniel, Woller, Norman, Engelskircher, Sophie Anna, Hardtke, Svenja, Port, Kerstin, Ponzetta, Andrea, Steinmann, Eike, Cornberg, Markus, Hengst, Julia, Björkström, Niklas K., Wedemeyer, Heiner
Published in European journal of immunology (01.03.2022)
Published in European journal of immunology (01.03.2022)
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PD-1/CTLA-4 Blockade Leads to Expansion of CD8[sup.+]PD-1[sup.int] TILs and Results in Tumor Remission in Experimental Liver Cancer
Bufe, Sandra, Zimmermann, Artur, Ravens, Sarina, Prinz, Immo, Buitrago-Molina, Laura Elisa, Geffers, Robert, Woller, Norman
Published in Liver cancer (Basel ) (01.06.2023)
Published in Liver cancer (Basel ) (01.06.2023)
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CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations
Nimanong, Supot, Ostroumov, Dmitrij, Wingerath, Jessica, Knocke, Sarah, Woller, Norman, Gürlevik, Engin, Falk, Christine S, Manns, Michael P, Kühnel, Florian, Wirth, Thomas C
Published in Cancer research (Chicago, Ill.) (15.04.2017)
Published in Cancer research (Chicago, Ill.) (15.04.2017)
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