Search Results - "WOLFGANG, SCHWEDE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

by Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea
Published in Molecular cancer therapeutics (01.11.2018)

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Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies

Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies

by Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)

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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179

by Mowat, Jeffrey, Ehrmann, Alexander H. M, Christian, Sven, Sperl, Carolyn, Menz, Stephan, Günther, Judith, Hillig, Roman C, Bauser, Marcus, Schwede, Wolfgang
Published in ACS medicinal chemistry letters (10.03.2022)

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Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development

by Klar, Ulrich, Buchmann, Bernd, Schwede, Wolfgang, Skuballa, Werner, Hoffmann, Jens, Lichtner, Rosemarie B.
Published in Angewandte Chemie International Edition (04.12.2006)

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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist

Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist

by Fuhrmann, Ulrike, Hess-Stumpp, Holger, Cleve, Arwed, Neef, Günter, Schwede, Wolfgang, Hoffmann, Jens, Fritzemeier, Karl-Heinrich, Chwalisz, Kristof
Published in Journal of medicinal chemistry (28.12.2000)

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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor

by Mowat, Jeffrey, Christian, Sven, Sperl, Carolyn, Ehrmann, Alexander, Menz, Stephan, Guenther, Judith, Hillig, Roman, Bauser, Marcus, Haegebarth, Andrea, Schwede, Wolfgang
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction

7α,15α-Ethano bridged steroids. Synthesis and progesterone receptor interaction

by Egner, Ursula, Fritzemeier, Karl-Heinrich, Halfbrodt, Wolfgang, Heinrich, Nikolaus, Kuhnke, Joachim, Müller-Fahrnow, Anke, Neef, Günter, Schöllkopf, Klaus, Schwede, Wolfgang
Published in Tetrahedron (01.09.1999)

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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo

by Algire, Carolyn, Ehrmann, Alexander, Christian, Sven, Neuhaus, Roland, Menz, Stephan, Schwede, Wolfgang, Haerter, Michael, Haegebarth, Andrea
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)

Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)

by Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)

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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy

by Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Mowat, Jeffrey S., Ehrmann, Alexander, Menz, Stephan, Bauser, Marcus, Haegebarth, Andrea
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer

Abstract 4989: 3D spheroid screen yields SCD1 pathway inhibitors for the treatment of cancer

by Gruenewald, Sylvia, Sperl, Carolyn, Steigemann, Patrick, Walter, Alexander, Zacharias, Sylvia, Eberspaecher, Uwe, Neuhaus, Roland, Zorn, Ludwig, Schwede, Wolfgang, Thede, Kai, Christian, Sven
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies

BAY 1002670: a novel, highly potent and selective progesterone receptor modulator for gynaecological therapies

by Wagenfeld, Andrea, Bone, Wilhelm, Schwede, Wolfgang, Fritsch, Martin, Fischer, Oliver M., Moeller, Carsten
Published in Human reproduction (Oxford) (01.08.2013)

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Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

Abstract 317: 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

by Wenzel, Carsten, Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Neuhaus, Roland, Guenther, Judith, Liu, Ningshu, Raese, Sebastian, Parczyk, Karsten, Prechtl, Stefan, Steigemann, Patrick
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines

Abstract 2682: Small molecule targeting the lipoic acid post-translational modification impacts proliferation of colorectal and PIK3CA-mutant cell lines

by Doherty, Laura, Sangpo, Tenzin, Tsvetkov, Peter, Davis, John, Dianati, Navid, Schwede, Wolfgang, Zimmermann, Katja, Evans, Laura, Amatucci, Aldo, Seidel, Henrik, Kamburov, Atanas, Akcay, Gizem, Golub, Todd, Eheim, Ashley, Burkhardt, Nils, Eis, Knut, Christian, Sven, Rees, Matt, Roth, Jennifer
Published in Cancer research (Chicago, Ill.) (15.06.2022)

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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

by HOFFMANN, Jens, VILALE, Ilio, PANARETAKIS, Theocharis, SIEMEISTER, Gerhard, LAGE, Hermann, NANTY, Lisa, HAMMER, Stefanie, MITTELSTAEDT, Kevin, WINSEL, Sebastian, ESCHENBRENNER, Julia, CASTEDO, Maria, DEMARCHE, Carine, BUCHMANN, Bernd, KLAR, Ulrich, KROEMER, Guido, GALLUZZI, Lorenzo, SCHWEDE, Wolfgang, SENOVILLA, Laura, SKUBALLA, Werner, VIVET, Sonia, LICHTNER, Rosemarie B, VICENCIO, José M
Published in Cancer research (Chicago, Ill.) (01.07.2008)

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17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVE, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES

17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVE, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES

by WOLFGANG SCHWEDE, ANDREA ROTGERI, CARSTEN MOLLER, ULRICH KLAR, WILHELM BONE
Year of Publication 15.06.2017

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Patent

Inhibition of Proliferation and Fibrosis by Vitamin D Agonists—Impact for Uterine Leiomyoma

Inhibition of Proliferation and Fibrosis by Vitamin D Agonists—Impact for Uterine Leiomyoma

by Wagenfeld, Andrea, Moeller, Carsten, Sandner, Peter, Schwede, Wolfgang, Steinmeyer, Andreas, Zuegel, Ulrich
Published in Biology of reproduction (01.07.2011)

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Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system

Global gene expression profiling of progesterone receptor modulators in T47D cells provides a new classification system

by Afhüppe, Wiebke, Sommer, Anette, Müller, Jörg, Schwede, Wolfgang, Fuhrmann, Ulrike, Möller, Carsten
Published in The Journal of steroid biochemistry and molecular biology (2009)

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17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVES, METHOD OF PRODUCTION THEREOF AND USE THEREOF FOR TREATMENT OF DISEASES

17-HYDROXY-17-PENTAFLUOROETHYL-ESTRA-4,9(10)-DIEN-11-ARYL DERIVATIVES, METHOD OF PRODUCTION THEREOF AND USE THEREOF FOR TREATMENT OF DISEASES

by WOLFGANG SCHWEDE, ANDREA ROTGERI, CARSTEN MOLLER, ULRICH KLAR, WILHELM BONE
Year of Publication 08.10.2015

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Patent

Investigational developments for the treatment of progesterone-dependent diseases

Investigational developments for the treatment of progesterone-dependent diseases

by Möller, Carsten, Hoffmann, Jens, Kirkland, Thomas A, Schwede, Wolfgang
Published in Expert opinion on investigational drugs (01.04.2008)

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