Discovery and Characterization of Vicriviroc (SCH 417690), a CCR5 Antagonist with Potent Activity against Human Immunodeficiency Virus Type 1
STRIZKI, Julie M, TREMBLAY, Cecile, TAGAT, Jayaram R, COX, Kathleen, PRIESTLEY, Tony, SOROTA, Steve, WEI HUANG, HIRSCH, Martin, REYES, Gregory R, BAROUDY, Bahige M, XU, Serena, WOJCIK, Lisa, WAGNER, Nicole, GONSIOREK, Waldemar, HIPKIN, R. William, CHOU, Chuan-Chu, PUGLIESE-SIVO, Catherine, YUSHI XIAO
Published in Antimicrobial Agents and Chemotherapy (01.12.2005)
Published in Antimicrobial Agents and Chemotherapy (01.12.2005)
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Mapping resistance to the CCR5 co-receptor antagonist vicriviroc using heterologous chimeric HIV-1 envelope genes reveals key determinants in the C2-V5 domain of gp120
Ogert, Robert A, Wojcik, Lisa, Buontempo, Catherine, Ba, Lei, Buontempo, Peter, Ralston, Robert, Strizki, Julie, Howe, John A
Published in Virology (New York, N.Y.) (10.04.2008)
Published in Virology (New York, N.Y.) (10.04.2008)
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Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)
McNicholas, Paul M, Mann, Paul A, Wojcik, Lisa, Qiu, Ping, Lee, Erin, McCarthy, Michael, Shen, Junwu, Black, Todd A, Strizki, Julie M
Published in Journal of acquired immune deficiency syndromes (1999) (01.03.2011)
Published in Journal of acquired immune deficiency syndromes (1999) (01.03.2011)
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HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use
Trkola, Alexandra, Kuhmann, Shawn E., Strizki, Julie M., Maxwell, Elizabeth, Ketas, Tom, Morgan, Tom, Pugach, Pavel, Xu, Serena, Wojcik, Lisa, Tagat, Jayaram, Palani, Anandan, Shapiro, Sherry, Clader, John W., McCombie, Stuart, Reyes, Gregory R., Baroudy, Bahige M., Moore, John P.
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2002)
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SCH-C (SCH 351125), An Orally Bioavailable, Small Molecule Antagonist of the Chemokine Receptor CCR5, is a Potent Inhibitor of HIV-1 Infection in vitro and in vivo
Strizki, Julie M., Xu, Serena, Wagner, Nicole E., Wojcik, Lisa, Liu, Jia, Hou, Yan, Endres, Michael, Palani, Anandan, Shapiro, Sherry, Clader, John W., Greenlee, William J., Tagat, Jayaram R., McCombie, Stuart, Cox, Kathleen, Fawzi, Ahmad B., Chou, Chuan-Chu, Pugliese-Sivo, Catherine, Davies, Liza, Moreno, Mary E., Ho, David D., Trkola, Alexandra, Stoddart, Cheryl A., Moore, John P., Reyes, Gregory R., Baroudy, Bahige M.
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2001)
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Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4
Whitehurst, Charles E, Yao, Zhiping, Murphy, Denise, Zhang, Mingxuan, Taremi, Shane, Wojcik, Lisa, Strizki, Julie M, Bracken, Jack D, Cheng, Cliff C, Yang, Xianshu, Shipps, Jr, Gerald W, Ziebell, Michael, Nickbarg, Elliott
Published in Combinatorial chemistry & high throughput screening (01.07.2012)
Published in Combinatorial chemistry & high throughput screening (01.07.2012)
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Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-[(2,4-Dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoro- methyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist
Tagat, Jayaram R, Steensma, Ruo W, McCombie, Stuart W, Nazareno, Dennis V, Lin, Sue-Ing, Neustadt, Bernard R, Cox, Kathleen, Xu, Serena, Wojcik, Lisa, Murray, Michael G, Vantuno, Nicole, Baroudy, Bahige M, Strizki, Julie M
Published in Journal of medicinal chemistry (11.10.2001)
Published in Journal of medicinal chemistry (11.10.2001)
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Clinical resistance to vicriviroc through adaptive V3 loop mutations in HIV-1 subtype D gp120 that alter interactions with the N-terminus and ECL2 of CCR5
Ogert, Robert A, Hou, Yan, Ba, Lei, Wojcik, Lisa, Qiu, Ping, Murgolo, Nicholas, Duca, Jose, Dunkle, Lisa M, Ralston, Robert, Howe, John A
Published in Virology (New York, N.Y.) (25.04.2010)
Published in Virology (New York, N.Y.) (25.04.2010)
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Quantifying the relationship between HIV-1 susceptibility to CCR5 antagonists and virus affinity for antagonist-occupied co-receptor
Buontempo, Peter J, Wojcik, Lisa, Buontempo, Catherine A, Ogert, Robert A, Strizki, Julie M, Howe, John A, Ralston, Robert
Published in Virology (New York, N.Y.) (20.12.2009)
Published in Virology (New York, N.Y.) (20.12.2009)
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Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-[(2,4-Dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3( S )-methyl-4-[1( S )-[4-(trifluoro- methyl)phenyl]ethyl]-1-piperazinyl]- piperidine N 1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist
Tagat, Jayaram R., Steensma, Ruo W., McCombie, Stuart W., Nazareno, Dennis V., Lin, Sue-Ing, Neustadt, Bernard R., Cox, Kathleen, Xu, Serena, Wojcik, Lisa, Murray, Michael G., Vantuno, Nicole, Baroudy, Bahige M., Strizki, Julie M.
Published in Journal of medicinal chemistry (01.10.2001)
Published in Journal of medicinal chemistry (01.10.2001)
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Differential production of interleukin 10 during human immunodeficiency virus infection
Chehimi, J, Ma, X, Chouaib, S, Zyad, A, Nagashunmugam, T, Wojcik, L, Chehimi, S, Nissim, L, Frank, I
Published in AIDS research and human retroviruses (10.08.1996)
Published in AIDS research and human retroviruses (10.08.1996)
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