NUDT2 initiates viral RNA degradation by removal of 5′-phosphates
Laudenbach, Beatrice T., Krey, Karsten, Emslander, Quirin, Andersen, Line Lykke, Reim, Alexander, Scaturro, Pietro, Mundigl, Sarah, Dächert, Christopher, Manske, Katrin, Moser, Markus, Ludwig, Janos, Wohlleber, Dirk, Kröger, Andrea, Binder, Marco, Pichlmair, Andreas
Published in Nature communications (25.11.2021)
Published in Nature communications (25.11.2021)
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Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver
Grünwald, Barbara, Harant, Veronika, Schaten, Susanne, Frühschütz, Monika, Spallek, Ria, Höchst, Bastian, Stutzer, Katharina, Berchtold, Sonja, Erkan, Mert, Prokopchuk, Olga, Martignoni, Marc, Esposito, Irene, Heikenwalder, Mathias, Gupta, Aayush, Siveke, Jens, Saftig, Paul, Knolle, Percy, Wohlleber, Dirk, Krüger, Achim
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
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Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection
Schneider, Annika, Kurz, Sandra, Manske, Katrin, Janas, Marianne, Heikenwälder, Mathias, Misgeld, Thomas, Aichler, Michaela, Weissmann, Sebastian Felix, Zischka, Hans, Knolle, Percy, Wohlleber, Dirk
Published in Scientific reports (11.06.2019)
Published in Scientific reports (11.06.2019)
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Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA
Schrom, Eva, Huber, Maja, Aneja, Manish, Dohmen, Christian, Emrich, Daniela, Geiger, Johannes, Hasenpusch, Günther, Herrmann-Janson, Annika, Kretzschmann, Verena, Mykhailyk, Olga, Pasewald, Tamara, Oak, Prajakta, Hilgendorff, Anne, Wohlleber, Dirk, Hoymann, Heinz-Gerd, Schaudien, Dirk, Plank, Christian, Rudolph, Carsten, Kubisch-Dohmen, Rebekka
Published in Molecular therapy. Nucleic acids (16.06.2017)
Published in Molecular therapy. Nucleic acids (16.06.2017)
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Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis
Schulte, Rike, Wohlleber, Dirk, Unrau, Ludmilla, Geers, Bernd, Metzger, Christina, Erhardt, Annette, Tiegs, Gisa, van Rooijen, Nico, Heukamp, Lukas C, Klotz, Luisa, Knolle, Percy A, Diehl, Linda
Published in International journal of molecular sciences (05.04.2020)
Published in International journal of molecular sciences (05.04.2020)
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Improving Therapeutic Vaccination against Hepatitis B—Insights from Preclinical Models of Immune Therapy against Persistent Hepatitis B Virus Infection
Knolle, Percy A., Huang, Li-Rung, Kosinska, Anna, Wohlleber, Dirk, Protzer, Ulrike
Published in Vaccines (Basel) (16.11.2021)
Published in Vaccines (Basel) (16.11.2021)
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Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance
Schölzel, Katrin, Schildberg, Frank A, Welz, Meike, Börner, Carolin, Geiger, Sergej, Kurts, Christian, Heikenwälder, Mathias, Knolle, Percy A, Wohlleber, Dirk
Published in Journal of hepatology (01.09.2014)
Published in Journal of hepatology (01.09.2014)
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Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity
Böttcher, Jan P., Schanz, Oliver, Wohlleber, Dirk, Abdullah, Zeinab, Debey-Pascher, Svenja, Staratschek-Jox, Andrea, Höchst, Bastian, Hegenbarth, Silke, Grell, Jessica, Limmer, Andreas, Atreya, Imke, Neurath, Markus F., Busch, Dirk H., Schmitt, Edgar, van Endert, Peter, Kolanus, Waldemar, Kurts, Christian, Schultze, Joachim L., Diehl, Linda, Knolle, Percy A.
Published in Cell reports (Cambridge) (28.03.2013)
Published in Cell reports (Cambridge) (28.03.2013)
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MHC Class I-Restricted TCR-Transgenic CD4 + T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo
Schober, Sebastian J, Thiede, Melanie, Gassmann, Hendrik, Prexler, Carolin, Xue, Busheng, Schirmer, David, Wohlleber, Dirk, Stein, Stefanie, Grünewald, Thomas G P, Busch, Dirk H, Richter, Guenther H S, Burdach, Stefan E G, Thiel, Uwe
Published in Cells (Basel, Switzerland) (29.06.2020)
Published in Cells (Basel, Switzerland) (29.06.2020)
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High precision-cut liver slice model to study cell-autonomous antiviral defense of hepatocytes within their microenvironment
Brugger, Marcus, Laschinger, Melanie, Lampl, Sandra, Schneider, Annika, Manske, Katrin, Esfandyari, Dena, Hüser, Norbert, Hartmann, Daniel, Steiger, Katja, Engelhardt, Stefan, Wohlleber, Dirk, Knolle, Percy A.
Published in JHEP reports (01.05.2022)
Published in JHEP reports (01.05.2022)
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TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation
Wohlleber, Dirk, Kashkar, Hamid, Gärtner, Katja, Frings, Marianne K., Odenthal, Margarete, Hegenbarth, Silke, Börner, Carolin, Arnold, Bernd, Hämmerling, Günter, Nieswandt, Bernd, van Rooijen, Nico, Limmer, Andreas, Cederbrant, Karin, Heikenwalder, Mathias, Pasparakis, Manolis, Protzer, Ulrike, Dienes, Hans-Peter, Kurts, Christian, Krönke, Martin, Knolle, Percy A.
Published in Cell reports (Cambridge) (27.09.2012)
Published in Cell reports (Cambridge) (27.09.2012)
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TOP-050 - “Swarm hunting” of virus-specific CD8 T cells together with auto-aggressive CD8 T cells to achieve efficient killing of virus-infected hepatocytes
Tenreiro, Ariane Eceiza, Dudek, Michael, Wohlleber, Dirk, Knolle, Percy A.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
Alfei, Francesca, Kanev, Kristiyan, Hofmann, Maike, Wu, Ming, Ghoneim, Hazem E., Roelli, Patrick, Utzschneider, Daniel T., von Hoesslin, Madlaina, Cullen, Jolie G., Fan, Yiping, Eisenberg, Vasyl, Wohlleber, Dirk, Steiger, Katja, Merkler, Doron, Delorenzi, Mauro, Knolle, Percy A., Cohen, Cyrille J., Thimme, Robert, Youngblood, Benjamin, Zehn, Dietmar
Published in Nature (London) (01.07.2019)
Published in Nature (London) (01.07.2019)
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TOP-053 - Rheostat function of liver sinusoidal endothelial cells and macrophages limiting antiviral CD8 T cell immunity in the liver
Fürst, Anna, Chattopadhyay, Sutirtha, Wintersteller, Hannah, Wohlleber, Dirk, Bosch, Miriam, Knolle, Percy A.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Journal Article
Rheostat function of liver sinusoidal endothelial cells and macrophages limiting antiviral CD8 T cell immunity in the liver
Fürst, Anna, Chattopadhyay, Sutirtha, Wintersteller, Hannah, Wohlleber, Dirk, Bosch, Miriam, Knolle, Percy A.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Analysis of Mitochondria by Single-Organelle Resolution
Harbauer, Angelika B, Schneider, Annika, Wohlleber, Dirk
Published in Annual review of analytical chemistry (Palo Alto, Calif.) (13.06.2022)
Published in Annual review of analytical chemistry (Palo Alto, Calif.) (13.06.2022)
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Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes
Wolf, Monika Julia, Adili, Arlind, Piotrowitz, Kira, Abdullah, Zeinab, Boege, Yannick, Stemmer, Kerstin, Ringelhan, Marc, Simonavicius, Nicole, Egger, Michèle, Wohlleber, Dirk, Lorentzen, Anna, Einer, Claudia, Schulz, Sabine, Clavel, Thomas, Protzer, Ulrike, Thiele, Christoph, Zischka, Hans, Moch, Holger, Tschöp, Matthias, Tumanov, Alexei V., Haller, Dirk, Unger, Kristian, Karin, Michael, Kopf, Manfred, Knolle, Percy, Weber, Achim, Heikenwalder, Mathias
Published in Cancer cell (13.10.2014)
Published in Cancer cell (13.10.2014)
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