Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration
Woodrow, Michael D., Ballantine, Stuart P., Barker, Michael D., Clarke, Beth J., Dawson, John, Dean, Tony W., Delves, Christopher J., Evans, Brian, Gough, Sharon L., Guntrip, Steven B., Holman, Stuart, Holmes, Duncan S., Kranz, Michael, Lindvaal, Mika K., Lucas, Fiona S., Neu, Margarete, Ranshaw, Lisa E., Solanke, Yemisi E., Somers, Don O., Ward, Peter, Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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Journal Article
Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors
Hamblin, J. Nicole, Angell, Tony D.R., Ballantine, Stuart P., Cook, Caroline M., Cooper, Anthony W.J., Dawson, John, Delves, Christopher J., Jones, Paul S., Lindvall, Mika, Lucas, Fiona S., Mitchell, Charlotte J., Neu, Margarete Y., Ranshaw, Lisa E., Solanke, Yemisi E., Somers, Don O., Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Pyrazolopyridines as potent PDE4B inhibitors: 5-Heterocycle SAR
Mitchell, Charlotte J., Ballantine, Stuart P., Coe, Diane M., Cook, Caroline M., Delves, Christopher J., Dowle, Mike D., Edlin, Chris D., Hamblin, J. Nicole, Holman, Stuart, Johnson, Martin R., Jones, Paul S., Keeling, Sue E., Kranz, Michael, Lindvall, Mika, Lucas, Fiona S., Neu, Margarete, Solanke, Yemisi E., Somers, Don O., Trivedi, Naimisha A., Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
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Journal Article
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: Optimisation for oral administration
Lunniss, Christopher J., Cooper, Anthony W.J., Eldred, Colin D., Kranz, Michael, Lindvall, Mika, Lucas, Fiona S., Neu, Margarete, Preston, Alex G.S., Ranshaw, Lisa E., Redgrave, Alison J., Ed Robinson, J., Shipley, Tracy J., Solanke, Yemisi E., Somers, Don O., Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
Swarbrick, Martin E., Beswick, Paul J., Gleave, Robert J., Green, Richard H., Bingham, Sharon, Bountra, Chas, Carter, Malcolm C., Chambers, Laura J., Chessell, Iain P., Clayton, Nick M., Collins, Sue D., Corfield, John A., Hartley, C. David, Kleanthous, Savvas, Lambeth, Paul F., Lucas, Fiona S., Mathews, Neil, Naylor, Alan, Page, Lee W., Payne, Jeremy J., Pegg, Neil A., Price, Helen S., Skidmore, John, Stevens, Alexander J., Stocker, Richard, Stratton, Sharon C., Stuart, Alastair J., Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Journal Article
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimi-dinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
SWARBRICK, Martin E, BESWICK, Paul J, COLLINS, Sue D, CORFIELD, John A, HARTLEY, C. David, KLEANTHOUS, Sawas, LAMBETH, Paul F, LUCAS, Fiona S, MATHEWS, Neil, NAYLOR, Alan, PAGE, Lee W, PAYNE, Jeremy J, GLEAVE, Robert J, PEGG, Neil A, PRICE, Helen S, SKIDMORE, John, STEVENS, Alexander J, STOCKER, Richard, STRATTON, Sharon C, STUART, Alastair J, WISEMAN, Joanne O, GREEN, Richard H, BINGHAM, Sharon, BOUNTRA, Chas, CARTER, Malcolm C, CHAMBERS, Laura J, CHESSELL, Lain P, CLAYTON, Nick M
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
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