The physics of cancer: the role of physical interactions and mechanical forces in metastasis
Wirtz, Denis, Konstantopoulos, Konstantinos, Searson, Peter C
Published in Nature reviews. Cancer (24.06.2011)
Published in Nature reviews. Cancer (24.06.2011)
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Journal Article
Multiple scale model for cell migration in monolayers: Elastic mismatch between cells enhances motility
Palmieri, Benoit, Bresler, Yony, Wirtz, Denis, Grant, Martin
Published in Scientific reports (02.07.2015)
Published in Scientific reports (02.07.2015)
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Journal Article
Three-dimensional cell migration does not follow a random walk
Wu, Pei-Hsun, Giri, Anjil, Sun, Sean X., Wirtz, Denis
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
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Journal Article
The Mechanobiology of Aging
Phillip, Jude M, Aifuwa, Ivie, Walston, Jeremy, Wirtz, Denis
Published in Annual review of biomedical engineering (07.12.2015)
Published in Annual review of biomedical engineering (07.12.2015)
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Journal Article
Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes
Agarwal, Amit, Wu, Pei-Hsun, Hughes, Ethan G., Fukaya, Masahiro, Tischfield, Max A., Langseth, Abraham J., Wirtz, Denis, Bergles, Dwight E.
Published in Neuron (Cambridge, Mass.) (08.02.2017)
Published in Neuron (Cambridge, Mass.) (08.02.2017)
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Journal Article
Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts
Gilkes, Daniele M., Bajpai, Saumendra, Chaturvedi, Pallavi, Wirtz, Denis, Semenza, Gregg L.
Published in The Journal of biological chemistry (12.04.2013)
Published in The Journal of biological chemistry (12.04.2013)
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Journal Article
Water Permeation Drives Tumor Cell Migration in Confined Microenvironments
Stroka, Kimberly M., Jiang, Hongyuan, Chen, Shih-Hsun, Tong, Ziqiu, Wirtz, Denis, Sun, Sean X., Konstantopoulos, Konstantinos
Published in Cell (24.04.2014)
Published in Cell (24.04.2014)
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Journal Article
Engineered Models of Confined Cell Migration
Paul, Colin D, Hung, Wei-Chien, Wirtz, Denis, Konstantopoulos, Konstantinos
Published in Annual review of biomedical engineering (11.07.2016)
Published in Annual review of biomedical engineering (11.07.2016)
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Journal Article
Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion
Ahmadzadeh, Hossein, Webster, Marie R., Behera, Reeti, Valencia, Angela M. Jimenez, Wirtz, Denis, Weeraratna, Ashani T., Shenoy, Vivek B.
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2017)
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Journal Article
A comparison of methods to assess cell mechanical properties
Wu, Pei-Hsun, Aroush, Dikla Raz-Ben, Asnacios, Atef, Chen, Wei-Chiang, Dokukin, Maxim E., Doss, Bryant L., Durand-Smet, Pauline, Ekpenyong, Andrew, Guck, Jochen, Guz, Nataliia V., Janmey, Paul A., Lee, Jerry S. H., Moore, Nicole M., Ott, Albrecht, Poh, Yeh-Chuin, Ros, Robert, Sander, Mathias, Sokolov, Igor, Staunton, Jack R., Wang, Ning, Whyte, Graeme, Wirtz, Denis
Published in Nature methods (01.07.2018)
Published in Nature methods (01.07.2018)
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Journal Article
Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis
GILKES, Daniele M, CHATURVEDI, Pallavi, BAJPAI, Saumendra, WONG, Carmen C, HONG WEI, PITCAIRN, Stephen, HUBBI, Maimon E, WIRTZ, Denis, SEMENZA, Gregg L
Published in Cancer research (Chicago, Ill.) (01.06.2013)
Published in Cancer research (Chicago, Ill.) (01.06.2013)
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Journal Article
Supramolecular Design of Unsymmetric Reverse Bolaamphiphiles for Cell‐Sensitive Hydrogel Degradation and Drug Release
Chakroun, Rami W., Sneider, Alexandra, Anderson, Caleb F., Wang, Feihu, Wu, Pei‐Hsun, Wirtz, Denis, Cui, Honggang
Published in Angewandte Chemie International Edition (09.03.2020)
Published in Angewandte Chemie International Edition (09.03.2020)
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Journal Article
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration
Jayatilaka, Hasini, Tyle, Pranay, Chen, Jonathan J., Kwak, Minsuk, Ju, Julia, Kim, Hyun Ji, Lee, Jerry S. H., Wu, Pei-Hsun, Gilkes, Daniele M., Fan, Rong, Wirtz, Denis
Published in Nature communications (26.05.2017)
Published in Nature communications (26.05.2017)
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Journal Article
Volume regulation and shape bifurcation in the cell nucleus
Kim, Dong-Hwee, Li, Bo, Si, Fangwei, Phillip, Jude M, Wirtz, Denis, Sun, Sean X
Published in Journal of cell science (15.09.2015)
Published in Journal of cell science (15.09.2015)
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Journal Article
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions
Fraley, Stephanie I., Wu, Pei-hsun, He, Lijuan, Feng, Yunfeng, Krisnamurthy, Ranjini, Longmore, Gregory D., Wirtz, Denis
Published in Scientific reports (01.10.2015)
Published in Scientific reports (01.10.2015)
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Journal Article
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
Gilkes, Daniele M, Xiang, Lisha, Lee, Sun Joo, Chaturvedi, Pallavi, Hubbi, Maimon E, Wirtz, Denis, Semenza, Gregg L
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
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Journal Article
Use of the p-values as a size-dependent function to address practical differences when analyzing large datasets
Gómez-de-Mariscal, Estibaliz, Guerrero, Vanesa, Sneider, Alexandra, Jayatilaka, Hasini, Phillip, Jude M., Wirtz, Denis, Muñoz-Barrutia, Arrate
Published in Scientific reports (22.10.2021)
Published in Scientific reports (22.10.2021)
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