APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells
Mohell, N, Alfredsson, J, Fransson, Å, Uustalu, M, Byström, S, Gullbo, J, Hallberg, A, Bykov, V J N, Björklund, U, Wiman, K G
Published in Cell death & disease (18.06.2015)
Published in Cell death & disease (18.06.2015)
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APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase
Peng, X, Zhang, M-Q-Z, Conserva, F, Hosny, G, Selivanova, G, Bykov, V J N, Arnér, E S J, Wiman, K G
Published in Cell death & disease (24.10.2013)
Published in Cell death & disease (24.10.2013)
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PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2
SHEN, J, VAKIFAHMETOGLU, H, STRIDH, H, ZHIVOTOVSKY, B, WIMAN, K. G
Published in Oncogene (30.10.2008)
Published in Oncogene (30.10.2008)
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Mutated and non‐mutated TP53 as targets in the treatment of leukaemia
Nahi, H., Selivanova, G., Lehmann, S., Möllgård, L., Bengtzen, S., Concha, H., Svensson, A., Wiman, K. G., Merup, M., Paul, C.
Published in British journal of haematology (01.05.2008)
Published in British journal of haematology (01.05.2008)
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The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?
Vilborg, A, Bersani, C, Wilhelm, M T, Wiman, K G
Published in Cell death and differentiation (01.09.2011)
Published in Cell death and differentiation (01.09.2011)
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PRIMA-1 APR-246 targets mutant forms of p53 family members p63 and p73
Rökaeus, N, Shen, J, Eckhardt, I, Bykov, V J N, Wiman, K G, Wilhelm, M T
Published in Oncogene (09.12.2010)
Published in Oncogene (09.12.2010)
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Proteomic identification of p53-dependent protein phosphorylation
RAHMAN-ROBLICK, R, HELLMAN, U, BECKER, S, BADER, F. G, AUER, G, WIMAN, K. G, ROBLICK, U. J
Published in Oncogene (14.08.2008)
Published in Oncogene (14.08.2008)
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Effects of PRIMA‐1 on chronic lymphocytic leukaemia cells with and without hemizygous p53 deletion
Nahi, H., Lehmann, S., Mollgard, L., Bengtzen, S., Selivanova, G., Wiman, K. G., Paul, C., Merup, M.
Published in British journal of haematology (01.11.2004)
Published in British journal of haematology (01.11.2004)
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PRIMA‐1 induces apoptosis in acute myeloid leukaemia cells with p53 gene deletion
Nahi, H., Merup, M., Lehmann, S., Bengtzen, S., Möllgård, L., Selivanova, G., Wiman, K. G., Paul, C.
Published in British journal of haematology (01.01.2006)
Published in British journal of haematology (01.01.2006)
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Small molecules that reactivate mutant p53
Bykov, V.J.N., Selivanova, G., Wiman, K.G.
Published in European journal of cancer (1990) (01.09.2003)
Published in European journal of cancer (1990) (01.09.2003)
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