An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models
Wilson, Alex W, Medhurst, Stephen J, Dixon, Claire I, Bontoft, Nick C, Winyard, Lisa A, Brackenborough, Kim T, De Alba, Jorge, Clarke, Christopher J, Gunthorpe, Martin J, Hicks, Gareth A, Bountra, Chas, McQueen, Daniel S, Chessell, Iain P
Published in European journal of pain (01.08.2006)
Published in European journal of pain (01.08.2006)
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Modeling techniques for post-tensioned cross-laminated timber rocking walls
Wilson, Alex W., Motter, Christopher J., Phillips, Adam R., Dolan, J. Daniel
Published in Engineering structures (15.09.2019)
Published in Engineering structures (15.09.2019)
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Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study
Durrenberger, Pascal F, Facer, Paul, Casula, Maria A, Yiangou, Yiangos, Gray, Roy A, Chessell, Iain P, Day, Nicola C, Collins, Sue D, Bingham, Sharon, Wilson, Alex W, Elliot, David, Birch, Rolfe, Anand, Praveen
Published in BMC neurology (04.01.2006)
Published in BMC neurology (04.01.2006)
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Discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a Selective CB2 Receptor Agonist for the Treatment of Inflammatory Pain
Giblin, Gerard M. P, O'Shaughnessy, Celestine T, Naylor, Alan, Mitchell, William L, Eatherton, Andrew J, Slingsby, Brian P, Rawlings, D. Anthony, Goldsmith, Paul, Brown, Andrew J, Haslam, Carl P, Clayton, Nick M, Wilson, Alex W, Chessell, Iain P, Wittington, Andrew R, Green, Richard
Published in Journal of medicinal chemistry (31.05.2007)
Published in Journal of medicinal chemistry (31.05.2007)
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Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a Brain Penetrant 5-Azaindole CB2 Agonist for the Treatment of Chronic Pain
Giblin, Gerard M. P, Billinton, Andrew, Briggs, Michael, Brown, Andrew J, Chessell, Iain P, Clayton, Nick M, Eatherton, Andrew J, Goldsmith, Paul, Haslam, Carl, Johnson, Matthew R, Mitchell, William L, Naylor, Alan, Perboni, Alcide, Slingsby, Brian P, Wilson, Alex W
Published in Journal of medicinal chemistry (08.10.2009)
Published in Journal of medicinal chemistry (08.10.2009)
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Activation of CB1 and CB2 receptors attenuates the induction and maintenance of inflammatory pain in the rat
ELMES, Steven J. R, WINYARD, Lisa A, MEDHURST, Stephen J, CLAYTON, Nick M, WILSON, Alex W, KENDALL, David A, CHAPMAN, Victoria
Published in Pain (Amsterdam) (05.12.2005)
Published in Pain (Amsterdam) (05.12.2005)
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Collagen‐induced arthritis as a model of hyperalgesia: Functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade
Inglis, Julia J., Notley, Clare A., Essex, David, Wilson, Alex W., Feldmann, Marc, Anand, Praveen, Williams, Richard
Published in Arthritis and rheumatism (01.12.2007)
Published in Arthritis and rheumatism (01.12.2007)
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Pressure application measurement (PAM): A novel behavioural technique for measuring hypersensitivity in a rat model of joint pain
Barton, Nicola J., Strickland, Iain T., Bond, Susan M., Brash, Harry M., Bate, Simon T., Wilson, Alex W., Chessell, Iain P., Reeve, Alison J., McQueen, Daniel S.
Published in Journal of neuroscience methods (15.06.2007)
Published in Journal of neuroscience methods (15.06.2007)
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Changes in dorsal root ganglion CGRP expression in a chronic inflammatory model of the rat knee joint: differential modulation by rofecoxib and paracetamol
Staton, Penny C, Wilson, Alex W, Bountra, Chas, Chessell, Iain P, Day, Nicola C
Published in European journal of pain (01.04.2007)
Published in European journal of pain (01.04.2007)
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The discovery of 6 -[2 -(5 -chloro -2 -{[ (2,4 -difluorophenyl )-methyl ]oxy}phenyl ) -1 -cyclopenten -1 -yl ] -2 -pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain
GIBLIN, Gerard M. P, BIT, Rino A, HURST, David N, MICHEL, Anton D, NAYLOR, Alan, NOVELLI, Riccardo, SCOCCITTI, Tiziana, SPALDING, David, TANG, Sac P, WILSON, Alex W, WILSON, Rich, BROWN, Susan H, CHAIGNOT, Hélène M, CHOWDHURY, Anita, CHESSELL, Iain P, CLAYTON, Nicholas M, COLEMAN, Tanya, HALL, Adrian, HAMMOND, Beverley
Published in Bioorganic & medicinal chemistry letters (15.01.2007)
Published in Bioorganic & medicinal chemistry letters (15.01.2007)
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Pyridine-3-carboxamides as novel CB(2) agonists for analgesia
Mitchell, William L, Giblin, Gerard M P, Naylor, Alan, Eatherton, Andrew J, Slingsby, Brian P, Rawlings, Anthony D, Jandu, Karamjit S, Haslam, Carl P, Brown, Andrew J, Goldsmith, Paul, Clayton, Nick M, Wilson, Alex W, Chessell, Iain P, Green, Richard H, Whittington, Andrew R, Wall, Ian D
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
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Journal Article
Pyridine-3-carboxamides as novel CB2 agonists for analgesia
MITCHELL, William L, GIBLIN, Gerard M. P, CLAYTON, Nick M, WILSON, Alex W, CHESSELL, Iain P, GREEN, Richard H, WHITTINGTON, Andrew R, WALL, Ian D, NAYLOR, Alan, EATHERTON, Andrew J, SLINGSBY, Brian P, RAWLINGS, Anthony D, JANDU, Karamjit S, HASLAM, Carl P, BROWN, Andrew J, GOLDSMITH, Paul
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article
Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1 H -pyrrolo[3,2- c ]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a Brain Penetrant 5-Azaindole CB 2 Agonist for the Treatment of Chronic Pain
Giblin, Gerard M. P., Billinton, Andrew, Briggs, Michael, Brown, Andrew J., Chessell, Iain P., Clayton, Nick M., Eatherton, Andrew J., Goldsmith, Paul, Haslam, Carl, Johnson, Matthew R., Mitchell, William L., Naylor, Alan, Perboni, Alcide, Slingsby, Brian P., Wilson, Alex W.
Published in Journal of medicinal chemistry (08.10.2009)
Published in Journal of medicinal chemistry (08.10.2009)
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Journal Article
Pyridine-3-carboxamides as novel CB 2 agonists for analgesia
Mitchell, William L., Giblin, Gerard M.P., Naylor, Alan, Eatherton, Andrew J., Slingsby, Brian P., Rawlings, Anthony D., Jandu, Karamjit S., Haslam, Carl P., Brown, Andrew J., Goldsmith, Paul, Clayton, Nick M., Wilson, Alex W., Chessell, Iain P., Green, Richard H., Whittington, Andrew R., Wall, Ian D.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article
Pyridine-3-carboxamides as novel CB sub(2) agonists for analgesia
Mitchell, William L, Giblin, Gerard MP, Naylor, Alan, Eatherton, Andrew J, Slingsby, Brian P, Rawlings, Anthony D, Jandu, Karamjit S, Haslam, Carl P, Brown, Andrew J, Goldsmith, Paul, Clayton, Nick M, Wilson, Alex W, Chessell, Iain P, Green, Richard H, Whittington, Andrew R, Wall, Ian D
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
Published in Bioorganic & medicinal chemistry letters (01.01.2009)
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Journal Article
Activation of CB 1 and CB 2 receptors attenuates the induction and maintenance of inflammatory pain in the rat
Elmes, Steven J.R., Winyard, Lisa A., Medhurst, Stephen J., Clayton, Nick M., Wilson, Alex W., Kendall, David A., Chapman, Victoria
Published in Pain (Amsterdam) (2005)
Published in Pain (Amsterdam) (2005)
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