Primary and Acquired Resistance to Immune Checkpoint Inhibitors in Metastatic Melanoma
Gide, Tuba N, Wilmott, James S, Scolyer, Richard A, Long, Georgina V
Published in Clinical cancer research (15.03.2018)
Published in Clinical cancer research (15.03.2018)
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Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy
Gide, Tuba N., Quek, Camelia, Menzies, Alexander M., Tasker, Annie T., Shang, Ping, Holst, Jeff, Madore, Jason, Lim, Su Yin, Velickovic, Rebecca, Wongchenko, Matthew, Yan, Yibing, Lo, Serigne, Carlino, Matteo S., Guminski, Alexander, Saw, Robyn P.M., Pang, Angel, McGuire, Helen M., Palendira, Umaimainthan, Thompson, John F., Rizos, Helen, Silva, Ines Pires da, Batten, Marcel, Scolyer, Richard A., Long, Georgina V., Wilmott, James S.
Published in Cancer cell (11.02.2019)
Published in Cancer cell (11.02.2019)
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Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade
House, Imran G, Savas, Peter, Lai, Junyun, Chen, Amanda X Y, Oliver, Amanda J, Teo, Zhi L, Todd, Kirsten L, Henderson, Melissa A, Giuffrida, Lauren, Petley, Emma V, Sek, Kevin, Mardiana, Sherly, Gide, Tuba N, Quek, Camelia, Scolyer, Richard A, Long, Georgina V, Wilmott, James S, Loi, Sherene, Darcy, Phillip K, Beavis, Paul A
Published in Clinical cancer research (15.01.2020)
Published in Clinical cancer research (15.01.2020)
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Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study
Long, Georgina V, Atkinson, Victoria, Lo, Serigne, Sandhu, Shahneen, Guminski, Alexander D, Brown, Michael P, Wilmott, James S, Edwards, Jarem, Gonzalez, Maria, Scolyer, Richard A, Menzies, Alexander M, McArthur, Grant A
Published in The lancet oncology (01.05.2018)
Published in The lancet oncology (01.05.2018)
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Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition
Lee, Jenny H., Shklovskaya, Elena, Lim, Su Yin, Carlino, Matteo S., Menzies, Alexander M., Stewart, Ashleigh, Pedersen, Bernadette, Irvine, Malama, Alavi, Sara, Yang, Jean Y. H., Strbenac, Dario, Saw, Robyn P. M., Thompson, John F., Wilmott, James S., Scolyer, Richard A., Long, Georgina V., Kefford, Richard F., Rizos, Helen
Published in Nature communications (20.04.2020)
Published in Nature communications (20.04.2020)
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Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin
Park, Simone L., Buzzai, Anthony, Rautela, Jai, Hor, Jyh Liang, Hochheiser, Katharina, Effern, Maike, McBain, Nathan, Wagner, Teagan, Edwards, Jarem, McConville, Robyn, Wilmott, James S., Scolyer, Richard A., Tüting, Thomas, Palendira, Umaimainthan, Gyorki, David, Mueller, Scott N., Huntington, Nicholas D., Bedoui, Sammy, Hölzel, Michael, Mackay, Laura K., Waithman, Jason, Gebhardt, Thomas
Published in Nature (London) (17.01.2019)
Published in Nature (London) (17.01.2019)
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Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets
Newell, Felicity, Kong, Yan, Wilmott, James S., Johansson, Peter A., Ferguson, Peter M., Cui, Chuanliang, Li, Zhongwu, Kazakoff, Stephen H., Burke, Hazel, Dodds, Tristan J., Patch, Ann-Marie, Nones, Katia, Tembe, Varsha, Shang, Ping, van der Weyden, Louise, Wong, Kim, Holmes, Oliver, Lo, Serigne, Leonard, Conrad, Wood, Scott, Xu, Qinying, Rawson, Robert V., Mukhopadhyay, Pamela, Dummer, Reinhard, Levesque, Mitchell P., Jönsson, Göran, Wang, Xuan, Yeh, Iwei, Wu, Hong, Joseph, Nancy, Bastian, Boris C., Long, Georgina V., Spillane, Andrew J., Shannon, Kerwin F., Thompson, John F., Saw, Robyn P. M., Adams, David J., Si, Lu, Pearson, John V., Hayward, Nicholas K., Waddell, Nicola, Mann, Graham J., Guo, Jun, Scolyer, Richard A.
Published in Nature communications (18.07.2019)
Published in Nature communications (18.07.2019)
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Dynamic Changes in PD-L1 Expression and Immune Infiltrates Early During Treatment Predict Response to PD-1 Blockade in Melanoma
Vilain, Ricardo E, Menzies, Alexander M, Wilmott, James S, Kakavand, Hojabr, Madore, Jason, Guminski, Alexander, Liniker, Elizabeth, Kong, Benjamin Y, Cooper, Adam J, Howle, Julie R, Saw, Robyn P M, Jakrot, Valerie, Lo, Serigne, Thompson, John F, Carlino, Matteo S, Kefford, Richard F, Long, Georgina V, Scolyer, Richard A
Published in Clinical cancer research (01.09.2017)
Published in Clinical cancer research (01.09.2017)
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PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials
Madore, Jason, Vilain, Ricardo E., Menzies, Alexander M., Kakavand, Hojabr, Wilmott, James S., Hyman, Jessica, Yearley, Jennifer H., Kefford, Richard F., Thompson, John F., Long, Georgina V., Hersey, Peter, Scolyer, Richard A.
Published in Pigment cell and melanoma research (01.05.2015)
Published in Pigment cell and melanoma research (01.05.2015)
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Journal Article
CD103 + Tumor-Resident CD8 + T Cells Are Associated with Improved Survival in Immunotherapy-Naïve Melanoma Patients and Expand Significantly During Anti-PD-1 Treatment
Edwards, Jarem, Wilmott, James S, Madore, Jason, Gide, Tuba Nur, Quek, Camelia, Tasker, Annie, Ferguson, Angela, Chen, Jinbiao, Hewavisenti, Rehana, Hersey, Peter, Gebhardt, Thomas, Weninger, Wolfgang, Britton, Warwick J, Saw, Robyn P M, Thompson, John F, Menzies, Alexander M, Long, Georgina V, Scolyer, Richard A, Palendira, Umaimainthan
Published in Clinical cancer research (01.07.2018)
Published in Clinical cancer research (01.07.2018)
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Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity
Newell, Felicity, Wilmott, James S., Johansson, Peter A., Nones, Katia, Addala, Venkateswar, Mukhopadhyay, Pamela, Broit, Natasa, Amato, Carol M., Van Gulick, Robert, Kazakoff, Stephen H., Patch, Ann-Marie, Koufariotis, Lambros T., Lakis, Vanessa, Leonard, Conrad, Wood, Scott, Holmes, Oliver, Xu, Qinying, Lewis, Karl, Medina, Theresa, Gonzalez, Rene, Saw, Robyn P. M., Spillane, Andrew J., Stretch, Jonathan R., Rawson, Robert V., Ferguson, Peter M., Dodds, Tristan J., Thompson, John F., Long, Georgina V., Levesque, Mitchell P., Robinson, William A., Pearson, John V., Mann, Graham J., Scolyer, Richard A., Waddell, Nicola, Hayward, Nicholas K.
Published in Nature communications (16.10.2020)
Published in Nature communications (16.10.2020)
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Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Johansson, Peter A., Brooks, Kelly, Newell, Felicity, Palmer, Jane M., Wilmott, James S., Pritchard, Antonia L., Broit, Natasa, Wood, Scott, Carlino, Matteo S., Leonard, Conrad, Koufariotis, Lambros T., Nathan, Vaishnavi, Beasley, Aaron B., Howlie, Madeleine, Dawson, Rebecca, Rizos, Helen, Schmidt, Chris W., Long, Georgina V., Hamilton, Hayley, Kiilgaard, Jens F., Isaacs, Timothy, Gray, Elin S., Rolfe, Olivia J., Park, John J., Stark, Andrew, Mann, Graham J., Scolyer, Richard A., Pearson, John V., van Baren, Nicolas, Waddell, Nicola, Wadt, Karin W., McGrath, Lindsay A., Warrier, Sunil K., Glasson, William, Hayward, Nicholas K.
Published in Nature communications (15.05.2020)
Published in Nature communications (15.05.2020)
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Negative immune checkpoint regulation by VISTA: a mechanism of acquired resistance to anti-PD-1 therapy in metastatic melanoma patients
Kakavand, Hojabr, Jackett, Louise A, Menzies, Alexander M, Gide, Tuba N, Carlino, Matteo S, Saw, Robyn P M, Thompson, John F, Wilmott, James S, Long, Georgina V, Scolyer, Richard A
Published in Modern pathology (01.12.2017)
Published in Modern pathology (01.12.2017)
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Journal Article
Whole-genome landscapes of major melanoma subtypes
Hayward, Nicholas K., Wilmott, James S., Waddell, Nicola, Johansson, Peter A., Field, Matthew A., Nones, Katia, Patch, Ann-Marie, Kakavand, Hojabr, Alexandrov, Ludmil B., Burke, Hazel, Jakrot, Valerie, Kazakoff, Stephen, Holmes, Oliver, Leonard, Conrad, Sabarinathan, Radhakrishnan, Mularoni, Loris, Wood, Scott, Xu, Qinying, Waddell, Nick, Tembe, Varsha, Pupo, Gulietta M., De Paoli-Iseppi, Ricardo, Vilain, Ricardo E., Shang, Ping, Lau, Loretta M. S., Dagg, Rebecca A., Schramm, Sarah-Jane, Pritchard, Antonia, Dutton-Regester, Ken, Newell, Felicity, Fitzgerald, Anna, Shang, Catherine A., Grimmond, Sean M., Pickett, Hilda A., Yang, Jean Y., Stretch, Jonathan R., Behren, Andreas, Kefford, Richard F., Hersey, Peter, Long, Georgina V., Cebon, Jonathan, Shackleton, Mark, Spillane, Andrew J., Saw, Robyn P. M., López-Bigas, Núria, Pearson, John V., Thompson, John F., Scolyer, Richard A., Mann, Graham J.
Published in Nature (London) (11.05.2017)
Published in Nature (London) (11.05.2017)
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Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma
Long, Georgina V, Wilmott, James S, Capper, David, Preusser, Matthias, Zhang, Yuxiao E, Thompson, John F, Kefford, Richard F, von Deimling, Andreas, Scolyer, Richard A
Published in The American journal of surgical pathology (01.01.2013)
Published in The American journal of surgical pathology (01.01.2013)
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Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model
McKelvey, Kelly J, Hudson, Amanda L, Prasanna Kumar, Ramyashree, Wilmott, James S, Attrill, Grace H, Long, Georgina V, Scolyer, Richard A, Clarke, Stephen J, Wheeler, Helen R, Diakos, Connie I, Howell, Viive M
Published in PloS one (02.04.2020)
Published in PloS one (02.04.2020)
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UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas
Wong, Stephen Q, Waldeck, Kelly, Vergara, Ismael A, Schröder, Jan, Madore, Jason, Wilmott, James S, Colebatch, Andrew J, De Paoli-Iseppi, Ricardo, Li, Jason, Lupat, Richard, Semple, Timothy, Arnau, Gisela Mir, Fellowes, Andrew, Leonard, J Helen, Hruby, George, Mann, Graham J, Thompson, John F, Cullinane, Carleen, Johnston, Meredith, Shackleton, Mark, Sandhu, Shahneen, Bowtell, David D L, Johnstone, Ricky W, Fox, Stephen B, McArthur, Grant A, Papenfuss, Anthony T, Scolyer, Richard A, Gill, Anthony J, Hicks, Rodney J, Tothill, Richard W
Published in Cancer research (Chicago, Ill.) (15.12.2015)
Published in Cancer research (Chicago, Ill.) (15.12.2015)
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Selective BRAF Inhibitors Induce Marked T-cell Infiltration into Human Metastatic Melanoma
WILMOTT, James S, LONG, Georgina V, HOWLE, Julie R, HAYDU, Lauren E, SHARMA, Raghwa N, THOMPSON, John F, KEFFORD, Richard F, HERSEY, Peter, SCOLYER, Richard A
Published in Clinical cancer research (01.03.2012)
Published in Clinical cancer research (01.03.2012)
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Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome
Simpson, Rebecca C., Shanahan, Erin R., Batten, Marcel, Reijers, Irene L. M., Read, Mark, Silva, Ines P., Versluis, Judith M., Ribeiro, Rosilene, Angelatos, Alexandra S., Tan, Jian, Adhikari, Chandra, Menzies, Alexander M., Saw, Robyn P. M., Gonzalez, Maria, Shannon, Kerwin F., Spillane, Andrew J., Velickovic, Rebecca, Lazar, Alexander J., Damania, Ashish V., Mishra, Aditya K., Chelvanambi, Manoj, Banerjee, Anik, Ajami, Nadim J., Wargo, Jennifer A., Macia, Laurence, Holmes, Andrew J., Wilmott, James S., Blank, Christian U., Scolyer, Richard A., Long, Georgina V.
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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