4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors
Churcher, Ian, Beher, Dirk, Best, Jonathan D., Castro, José L., Clarke, Earl E., Gentry, Amy, Harrison, Timothy, Hitzel, Laure, Kay, Euan, Kerrad, Sonia, Lewis, Huw D., Morentin-Gutierrez, Pablo, Mortishire-Smith, Russell, Oakley, Paul J., Reilly, Michael, Shaw, Duncan E., Shearman, Mark S., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D.J.
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
Published in Bioorganic & medicinal chemistry letters (15.01.2006)
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Design and Synthesis of Highly Potent Benzodiazepine γ-Secretase Inhibitors: Preparation of (2S,3R)-3-(3,4- Difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]- diazepin-3-yl)butyramide by Use of an Asymmetric Ireland−Claisen Rearrangement
Churcher, Ian, Williams, Susie, Kerrad, Sonia, Harrison, Timothy, Castro, José L, Shearman, Mark S, Lewis, Huw D, Clarke, Earl E, Wrigley, Jonathan D. J, Beher, Dirk, Tang, Yui S, Liu, Wensheng
Published in Journal of medicinal chemistry (05.06.2003)
Published in Journal of medicinal chemistry (05.06.2003)
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A new series of potent benzodiazepine γ-secretase inhibitors
Churcher, Ian, Ashton, Kate, Butcher, John W., Clarke, Earl E., Harrison, Timothy, Lewis, Huw D., Owens, Andrew P., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D.J.
Published in Bioorganic & medicinal chemistry letters (20.01.2003)
Published in Bioorganic & medicinal chemistry letters (20.01.2003)
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Non-invasive detection of hypoglycaemia using a novel, fully biocompatible and patient friendly alarm system
Chen, Mimi, Daly, Mark, Williams, Natt, Williams, Susie, Williams, Candy, Williams, Gareth
Published in BMJ (23.12.2000)
Published in BMJ (23.12.2000)
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Design and Synthesis of Highly Potent Benzodiazepine γ-Secretase Inhibitors: Preparation of (2 S ,3 R )-3-(3,4- Difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy- N -((3 S )-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1 H -benzo[ e ][1,4]- diazepin-3-yl)butyramide by Use of an Asymmetric Ireland−Claisen Rearrangement
Churcher, Ian, Williams, Susie, Kerrad, Sonia, Harrison, Timothy, Castro, José L., Shearman, Mark S., Lewis, Huw D., Clarke, Earl E., Wrigley, Jonathan D. J., Beher, Dirk, Tang, Yui S., Liu, Wensheng
Published in Journal of medicinal chemistry (01.06.2003)
Published in Journal of medicinal chemistry (01.06.2003)
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Journal Article
Design and synthesis of highly potent benzodiazepine γ-secretase inhibitors: Preparation of (2S, 3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-1-methyl-2-o xo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement
CHURCHER, Ian, WILLIAMS, Susie, TANG, Yui S, WENSHENG LIU, KERRAD, Sonia, HARRISON, Timothy, CASTRO, José L, SHEARMAN, Mark S, LEWIS, Huw D, CLARKE, Earl E, WRIGLEY, Jonathan D. J, BEHER, Dirk
Published in Journal of medicinal chemistry (2003)
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Published in Journal of medicinal chemistry (2003)
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An interesting neighbor in Oklahoma
Susie Williams-Allen The Purcell (Okla.) Register
Published in Deseret news (Salt Lake City, Utah : 1964) (13.11.2009)
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Published in Deseret news (Salt Lake City, Utah : 1964) (13.11.2009)
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A New Series of Potent Benzodiazepine γ-Secretase Inhibitors
Churcher, Ian, Ashton, Kate, Butcher, John W., Clarke, Earl E., Harrison, Timothy, Lewis, Huw D., Owens, Andrew P., Teall, Martin R., Williams, Susie, Wrigley, Jonathan D. J.
Published in ChemInform (06.05.2003)
Published in ChemInform (06.05.2003)
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