The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
Weiss, Greta E, Ragotte, Robert J, Quinkert, Doris, Lias, Amelia M, Dans, Madeline G, Boulet, Coralie, Looker, Oliver, Ventura, Olivia D, Williams, Barnabas G, Crabb, Brendan S, Draper, Simon J, Gilson, Paul R
Published in PLoS pathogens (01.09.2023)
Published in PLoS pathogens (01.09.2023)
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Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Williams, Barnabas G., King, Lloyd D. W., Pulido, David, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Ragotte, Robert J., Davies, Hannah, Barrett, Jordan R., McHugh, Kirsty, Rigby, Cassandra A., Alanine, Daniel G. W., Barfod, Lea, Shea, Michael W., Cowley, Li An, Dabbs, Rebecca A., Pattinson, David J., Douglas, Alexander D., Lyth, Oliver R., Illingworth, Joseph J., Jin, Jing, Carnrot, Cecilia, Kotraiah, Vinayaka, Christen, Jayne M., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Skinner, Katherine, Miura, Kazutoyo, Long, Carole A., Higgins, Matthew K., Draper, Simon J.
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies
Alanine, Daniel G.W., Quinkert, Doris, Kumarasingha, Rasika, Mehmood, Shahid, Donnellan, Francesca R., Minkah, Nana K., Dadonaite, Bernadeta, Diouf, Ababacar, Galaway, Francis, Silk, Sarah E., Jamwal, Abhishek, Marshall, Jennifer M., Miura, Kazutoyo, Foquet, Lander, Elias, Sean C., Labbé, Geneviève M., Douglas, Alexander D., Jin, Jing, Payne, Ruth O., Illingworth, Joseph J., Pattinson, David J., Pulido, David, Williams, Barnabas G., de Jongh, Willem A., Wright, Gavin J., Kappe, Stefan H.I., Robinson, Carol V., Long, Carole A., Crabb, Brendan S., Gilson, Paul R., Higgins, Matthew K., Draper, Simon J.
Published in Cell (27.06.2019)
Published in Cell (27.06.2019)
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Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype
Barrett, Jordan R., Pipini, Dimitra, Wright, Nathan D., Cooper, Andrew J.R., Gorini, Giacomo, Quinkert, Doris, Lias, Amelia M., Davies, Hannah, Rigby, Cassandra A., Aleshnick, Maya, Williams, Barnabas G., Bradshaw, William J., Paterson, Neil G., Martinson, Thomas, Kirtley, Payton, Picard, Luc, Wiggins, Christine D., Donnellan, Francesca R., King, Lloyd D.W., Wang, Lawrence T., Popplewell, Jonathan F., Silk, Sarah E., de Ruiter Swain, Jed, Skinner, Katherine, Kotraiah, Vinayaka, Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Minassian, Angela M., Lauffenburger, Douglas A., Miura, Kazutoyo, Long, Carole A., Wilder, Brandon K., Koekemoer, Lizbé, Tan, Joshua, Nielsen, Carolyn M., McHugh, Kirsty, Draper, Simon J.
Published in Cell (05.09.2024)
Published in Cell (05.09.2024)
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Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies
King, Lloyd D.W., Pulido, David, Barrett, Jordan R., Davies, Hannah, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Pattinson, David J., Diouf, Ababacar, Williams, Barnabas G., McHugh, Kirsty, Rodrigues, Ana, Rigby, Cassandra A., Strazza, Veronica, Suurbaar, Jonathan, Rees-Spear, Chloe, Dabbs, Rebecca A., Ishizuka, Andrew S., Zhou, Yu, Gupta, Gaurav, Jin, Jing, Li, Yuanyuan, Carnrot, Cecilia, Minassian, Angela M., Campeotto, Ivan, Fleishman, Sarel J., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Long, Carole A., Miura, Kazutoyo, Ashfield, Rebecca, Skinner, Katherine, Howarth, Mark R., Biswas, Sumi, Draper, Simon J.
Published in Cell reports. Medicine (16.07.2024)
Published in Cell reports. Medicine (16.07.2024)
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Journal Article
The Dual Action of Human Antibodies Specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking Invasion and Inactivating Extracellular Merozoites
Weiss, Greta E, Ragotte, Robert J, Quinkert, Doris, Lias, Amelia M, Dans, Madeline G, Boulet, Coralie, Williams, Barnabas G, Crabb, Brendan S, Draper, Simon J, Gilson, Paul R
Published in bioRxiv (07.02.2023)
Published in bioRxiv (07.02.2023)
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Paper
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Williams, Barnabas G, King, Lloyd Dw, Pulido, David, Quinker, Doris, Lias, Amlia M, Silk, Sarah E, Ragotte, Robert J, Davies, Hannah, Barrett, Jordan R, Mchugh, Kirsty, Rigby, Cassandra A, Alanine, Daniel Gw, Barfod, Lea, Shea, Michael W, Li An Cowley, Dabbs, Rebecca A, Pattinson, David J, Douglas, Alexander D, Lyth, Oliver R, Illingworth, Joseph K, Jin, Jing, Carnot, Cecilia, Kotraiah, Vinayaka, Christen, Jayne M, Noe, Amy R, Macgill, Randall S, King, Crichter, Birkett, Ahsley J, Soisson, Lorraine A, Skinner, Katherine, Miura, Kazutoyo, Long, Carole A, Higgins, Matthew K, Draper, Simon J
Published in bioRxiv (08.02.2024)
Published in bioRxiv (08.02.2024)
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Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies
King, Lloyd D W, Pulido, David, Barrett, Jordan R, Davies, Hannah, Quinkert, Doris, Lias, Amelia M, Silk, Sarah E, Pattinson, David J, Diouf, Ababacar, Williams, Barnabas G, Mchugh, Kirsty, Rodrigues, Ana, Rigby, Cassandra A, Strazza, Veronica, Suurbaar, Jonathan, Rees-Spear, Chloe, Dabbs, Rebecca A, Ishizuka, Andrew S, Zhou, Yu, Gupta, Gaurav, Jin, Jing, Li, Yuanyuan, Carnrot, Cecilia, Minassian, Angela M, Campeotto, Ivan, Fleishman, Sarel J, Noe, Amy R, Macgill, Randall S, C Richter King, Birkett, Ashley J, Soisson, Lorraine A, Long, Carole A, Miura, Kazutoyo, Ashfield, Rebecca, Skinner, Katherine, Howarth, Mark, Biswas, Sumi, Draper, Simon J
Published in bioRxiv (05.01.2024)
Published in bioRxiv (05.01.2024)
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