Metabotropic Glutamate2 Receptors Play a Key Role in Modulating Head Twitches Induced by a Serotonergic Hallucinogen in Mice
Benvenga, Mark J., Chaney, Stephen F., Baez, Melvyn, Britton, Thomas C., Hornback, William J., Monn, James A., Marek, Gerard J.
Published in Frontiers in pharmacology (15.03.2018)
Published in Frontiers in pharmacology (15.03.2018)
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Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)
Johnson, Michael P, Barda, David, Britton, Thomas C, Emkey, Renee, Hornback, William J, Jagdmann, G Erik, McKinzie, David L, Nisenbaum, Eric S, Tizzano, Joseph P, Schoepp, Darryle D
Published in Psychopharmacology (01.04.2005)
Published in Psychopharmacology (01.04.2005)
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The First Total Synthesis of Lipid II: The Final Monomeric Intermediate in Bacterial Cell Wall Biosynthesis
VanNieuwenhze, Michael S, Mauldin, Scott C, Zia-Ebrahimi, Mohammad, Winger, Brian E, Hornback, William J, Saha, Shankar L, Aikins, James A, Blaszczak, Larry C
Published in Journal of the American Chemical Society (10.04.2002)
Published in Journal of the American Chemical Society (10.04.2002)
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IAM chromatography: an in vitro screen for predicting drug membrane permeability
Pidgeon, Charles, Ong, Shaowei, Liu, Hanlan, Qiu, Xiaoxing, Pidgeon, Mary, Dantzig, Anne H, Munroe, John, Hornback, William J, Kasher, Jeffery S
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
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A novel class of AMPA receptor allosteric modulators. Part 1: Design, synthesis, and SAR of 3-aryl-4-cyano-5-substituted-heteroaryl-2-carboxylic acid derivatives
Fernandez, Maria-Carmen, Castaño, Ana, Dominguez, Esteban, Escribano, Ana, Jiang, Delu, Jimenez, Alma, Hong, Eric, Hornback, William J., Nisenbaum, Eric S., Rankl, Nancy, Tromiczak, Eric, Vaught, Grant, Zarrinmayeh, Hamideh, Zimmerman, Dennis M.
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
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A novel class of positive allosteric modulators of AMPA receptors : Design, synthesis, and structure-activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, LY2059346
ZARRINMAYEH, Hamideh, TROMICZAK, Eric, HORNBACK, William J, NISENBAUM, Eric S, ZIMMERMAN, Dennis M, RANKL, Nancy, HO, Ken H, DOMINGUEZ, Esteban, CASTANO, Ana, ESCRIBANO, Ana, FERNANDEZ, Carmen, JIMENEZ, Alma
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
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Molecular Basis for the Resistance of Influenza Viruses to 4-Guanidino-Neu5Ac2en
STASCHKE, KIRK A., COLACINO, JOSEPH M., BAXTER, ANGELA J., AIR, GILLIAN M., BANSAL, ANJU, HORNBACK, WILLIAM J., MUNROE, JOHN E., LAVER, W.GRAEME
Published in Virology (New York, N.Y.) (20.12.1995)
Published in Virology (New York, N.Y.) (20.12.1995)
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Metabotropic Glutamate 2 Receptors Play a Key Role in Modulating Head Twitches Induced by a Serotonergic Hallucinogen in Mice
Benvenga, Mark J, Chaney, Stephen F, Baez, Melvyn, Britton, Thomas C, Hornback, William J, Monn, James A, Marek, Gerard J
Published in Frontiers in pharmacology (2018)
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Published in Frontiers in pharmacology (2018)
Journal Article
Comparative reactivity of 1-carba-1-dethiacephalosporins with cephalosporins
Blaszczak, Larry C, Brown, Raymond F, Cook, Gwendolyn K, Hornback, William J, Indelicato, Joseph M, Jordan, Chris L, Katner, Alan S, Kinnick, Michael D, McDonald, John H
Published in Journal of medicinal chemistry (01.06.1990)
Published in Journal of medicinal chemistry (01.06.1990)
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A novel class of positive allosteric modulators of AMPA receptors: Design, synthesis, and structure–activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1 H-pyrrole-2-carboxylic acid, LY2059346
Zarrinmayeh, Hamideh, Tromiczak, Eric, Zimmerman, Dennis M., Rankl, Nancy, Ho, Ken H., Dominguez, Esteban, Castaño, Ana, Escribano, Ana, Fernandez, Carmen, Jimenez, Alma, Hornback, William J., Nisenbaum, Eric S.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Metabotropic glutamate 2 receptor potentiators : receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s): Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets
JOHNSON, Michael P, BARDA, David, BRITTON, Thomas C, EMKEY, Renee, HORNBACK, William J, JAGDMANN, G. Erik, MCKINZIE, David L, NISENBAUM, Eric S, TIZZANO, Joseph P, SCHOEPP, Darryle D
Published in Psychopharmacologia (2005)
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Published in Psychopharmacologia (2005)
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SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITIES OF 3-THIAZOL-4-YL-1-GARB A-1-DETHIACEPH ALOSPORINS
HORNBACK, WILLIAM J., MUNROE, JOHN E., COUNTER, FRED T.
Published in The Journal of Antibiotics (25.09.1994)
Published in The Journal of Antibiotics (25.09.1994)
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Journal Article
Potent, orally bioavailable HIV-1 protease inhibitors containing noncoded D-amino acids
Munroe, John E., Shepherd, Timothy A., Jungheim, Louis N., Hornback, William J., Hatch, Steve D., Muesing, Mark A., Wiskerchen, MaryAnn, Su, Kenneth S., Campanale, Kristina M., Baxter, Angela J., Colacino, Joseph M.
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
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Journal Article
Ly316340: A potent HIV-1 protease inhibitor containing a high affinity octahydrothienopyridine hydroxyethylamine isostere
Munroe, John E., Hornback, William J., Campbell, Jack B., Ouellette, Michael A., Hatch, Steve D., Muesing, Mark A., Wiskerchen, Mary Ann, Baxter, Angela J., Su, Ken, Campanale, Kristina
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
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Journal Article
Synthesis and pharmacokinetics of potent carbamate HIV-1 protease inhibitors containing novel high affinity hydroxyethylamine isosteres
Hornback, William J., Munroe, John E., Shepherd, Timothy A., Hatch, Steve D., Muesing, Mark A., Wiskerchen, MaryAnn, Colacino, Joseph M., Baxter, Angela J., Su, Kenneth S., Campanale, Kristina M.
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
Published in Bioorganic & medicinal chemistry letters (07.12.1995)
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