Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy
Le, Kang, Soth, Michael J., Cross, Jason B., Liu, Gang, Ray, William J., Ma, Jiacheng, Goodwani, Sunil G., Acton, Paul J., Buggia-Prevot, Virginie, Akkermans, Onno, Barker, John, Conner, Michael L., Jiang, Yongying, Liu, Zhen, McEwan, Paul, Warner-Schmidt, Jennifer, Xu, Alan, Zebisch, Matthias, Heijnen, Cobi J., Abrahams, Brett, Jones, Philip
Published in Journal of medicinal chemistry (27.07.2023)
Published in Journal of medicinal chemistry (27.07.2023)
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Journal Article
Selective activation of the M₁ muscarinic acetylcholine receptor achieved by allosteric potentiation
Ma, Lei, Seager, Matthew, Wittmann, Marion, Jacobson, Marlene, Bickel, Denise, Burno, Maryann, Jones, Keith, Graufelds, Valerie Kuzmick, Xu, Guangping, Pearson, Michelle, McCampbell, Alexander, Gaspar, Renee, Shughrue, Paul, Danziger, Andrew, Regan, Christopher, Flick, Rose, Pascarella, Danette, Garson, Susan, Doran, Scott, Kreatsoulas, Constantine, Veng, Lone, Lindsley, Craig W, Shipe, William, Kuduk, Scott, Sur, Cyrille, Kinney, Gene, Seabrook, Guy R, Ray, William J
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.2009)
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Journal Article
Enhanced histamine H2 excitation of striatal cholinergic interneurons in l -DOPA-induced dyskinesia
Lim, Sean Austin O, Xia, Rong, Ding, Yunmin, Won, Lisa, Ray, William J, Hitchcock, Stephen A, McGehee, Daniel S, Kang, Un Jung
Published in Neurobiology of disease (01.04.2015)
Published in Neurobiology of disease (01.04.2015)
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Journal Article
Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions
Goodwani, Sunil, Fernandez, Celia, Acton, Paul J, Buggia-Prevot, Virginie, McReynolds, Morgan L, Ma, Jiacheng, Hu, Cheng Hui, Hamby, Mary E, Jiang, Yongying, Le, Kang, Soth, Michael J, Jones, Philip, Ray, William J
Published in International journal of molecular sciences (09.07.2020)
Published in International journal of molecular sciences (09.07.2020)
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Sex-Dependent Liver Gene Expression Is Extensive and Largely Dependent upon Signal Transducer and Activator of Transcription 5b (STAT5b): STAT5b-Dependent Activation of Male Genes and Repression of Female Genes Revealed by Microarray Analysis
Clodfelter, Karl H, Holloway, Minita G, Hodor, Paul, Park, Soo-Hee, Ray, William J, Waxman, David J
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2006)
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2006)
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Journal Article
Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing
Camargo, Luiz Miguel, Zhang, Xiaohua Douglas, Loerch, Patrick, Caceres, Ramon Miguel, Marine, Shane D, Uva, Paolo, Ferrer, Marc, de Rinaldis, Emanuele, Stone, David J, Majercak, John, Ray, William J, Yi-An, Chen, Shearman, Mark S, Mizuguchi, Kenji
Published in PloS one (27.02.2015)
Published in PloS one (27.02.2015)
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Journal Article
Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer’s disease
Beckmann, Adrian, Ramirez, Paulino, Gamez, Maria, Gonzalez, Elias, De Mange, Jasmine, Bieniek, Kevin F., Ray, William J., Frost, Bess
Published in iScience (17.03.2023)
Published in iScience (17.03.2023)
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Journal Article
MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate
Beshore, Douglas C., N. Di Marco, Christina, Chang, Ronald K., Greshock, Thomas J., Ma, Lei, Wittmann, Marion, Seager, Matthew A., Koeplinger, Kenneth A., Thompson, Charles D., Fuerst, Joy, Hartman, George D., Bilodeau, Mark T., Ray, William J., Kuduk, Scott D.
Published in ACS medicinal chemistry letters (12.07.2018)
Published in ACS medicinal chemistry letters (12.07.2018)
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Journal Article
Future-oriented decision-making in Generalized Anxiety Disorder is evident across different versions of the Iowa Gambling Task
Mueller, Erik M, Nguyen, Jennifer, Ray, William J, Borkovec, Thomas D
Published in Journal of behavior therapy and experimental psychiatry (01.06.2010)
Published in Journal of behavior therapy and experimental psychiatry (01.06.2010)
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Journal Article
Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of β-catenin
Gentile, Michael A, Nantermet, Pascale V, Vogel, Robert L, Phillips, Robert, Holder, Daniel, Hodor, Paul, Cheng, Chun, Dai, Hongyue, Freedman, Leonard P, Ray, William J
Published in Journal of molecular endocrinology (01.01.2010)
Published in Journal of molecular endocrinology (01.01.2010)
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Journal Article
Human Gamma Band Activity and Perception of a Gestalt
Keil, Andreas, Muller, Matthias M, Ray, William J, Gruber, Thomas, Elbert, Thomas
Published in The Journal of neuroscience (15.08.1999)
Published in The Journal of neuroscience (15.08.1999)
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Journal Article
A Regulatory Circuit Mediating Convergence between Nurr1 Transcriptional Regulation and Wnt Signaling
Kitagawa, Hirochika, Ray, William J., Glantschnig, Helmut, Nantermet, Pascale V., Yu, Yuanjiang, Leu, Chih-Tai, Harada, Shun-ichi, Kato, Shigeaki, Freedman, Leonard P.
Published in Molecular and Cellular Biology (01.11.2007)
Published in Molecular and Cellular Biology (01.11.2007)
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Journal Article
Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing
Camargo, Luiz Miguel, Zhang, Xiaohua Douglas, Loerch, Patrick, Caceres, Ramon Miguel, Marine, Shane D, Uva, Paolo, Ferrer, Marc, de Rinaldis, Emanuele, Stone, David J, Majercak, John, Ray, William J, Yi-An, Chen, Shearman, Mark S, Mizuguchi, Kenji
Published in PloS one (01.06.2015)
Published in PloS one (01.06.2015)
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Journal Article
LRRTM3 Promotes Processing of Amyloid-Precursor Protein by BACE1 and Is a Positional Candidate Gene for Late-Onset Alzheimer's Disease
Majercak, John, Ray, William J., Espeseth, Amy, Simon, Adam, Shi, Xiao-Ping, Wolffe, Carrie, Getty, Krista, Marine, Shane, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Bartz, Steven, Gates, Adam, Xu, Min, Huang, Qian, Ma, Lei, Shughrue, Paul, Burchard, Julja, Colussi, Dennis, Pietrak, Beth, Kahana, Jason, Beher, Dirk, Rosahl, Thomas, Shearman, Mark, Hazuda, Daria, Sachs, Alan B., Koblan, Kenneth S., Seabrook, Guy R., Stone, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2006)
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