Search Results - "WILDUM STEFFEN" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

by Zhou, Zheng, Hu, Taishan, Zhou, Xue, Wildum, Steffen, Garcia-Alcalde, Fernando, Xu, Zhiheng, Wu, Daitze, Mao, Yi, Tian, Xiaojun, Zhou, Yuan, Shen, Fang, Zhang, Zhisen, Tang, Guozhi, Najera, Isabel, Yang, Guang, Shen, Hong C., Young, John A. T., Qin, Ning
Published in Scientific reports (13.02.2017)

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In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

by MARSCHALL, Manfred, STAMMINGER, Thomas, URBAN, Andreas, WILDUM, Steffen, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger, LISCHKA, Peter
Published in Antimicrobial Agents and Chemotherapy (01.02.2012)

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Comprehensive assessment of amino acid substitutions in the trimeric RNA polymerase complex of influenza A virus detected in clinical trials of baloxavir marboxil

Comprehensive assessment of amino acid substitutions in the trimeric RNA polymerase complex of influenza A virus detected in clinical trials of baloxavir marboxil

by Hashimoto, Takashi, Baba, Keiko, Inoue, Kae, Okane, Miyako, Hata, Satoshi, Shishido, Takao, Naito, Akira, Wildum, Steffen, Omoto, Shinya
Published in Influenza and other respiratory viruses (01.05.2021)

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Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model

by Lee, Leo Yy, Zhou, Jie, Koszalka, Paulina, Frise, Rebecca, Farrukee, Rubaiyea, Baba, Keiko, Miah, Shahjahan, Shishido, Takao, Galiano, Monica, Hashimoto, Takashi, Omoto, Shinya, Uehara, Takeki, Mifsud, Edin J, Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Wildum, Steffen, Barclay, Wendy S, Hurt, Aeron C
Published in PLoS pathogens (06.05.2021)

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Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission

Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission

by Lee, Leo Yi Yang, Zhou, Jie, Frise, Rebecca, Goldhill, Daniel H, Koszalka, Paulina, Mifsud, Edin J, Baba, Kaoru, Noda, Takahiro, Ando, Yoshinori, Sato, Kenji, Yuki, Aoe-Ishikawa, Shishido, Takao, Uehara, Takeki, Wildum, Steffen, Zwanziger, Elke, Collinson, Neil, Kuhlbusch, Klaus, Clinch, Barry, Hurt, Aeron C, Barclay, Wendy S
Published in PLoS pathogens (01.04.2020)

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Contribution of Vpu, Env, and Nef to CD4 Down-Modulation and Resistance of Human Immunodeficiency Virus Type 1-Infected T Cells to Superinfection

Contribution of Vpu, Env, and Nef to CD4 Down-Modulation and Resistance of Human Immunodeficiency Virus Type 1-Infected T Cells to Superinfection

by WILDUM, Steffen, SCHINDLER, Michael, MÜNCH, Jan, KIRCHHOFF, Frank
Published in Journal of Virology (01.08.2006)

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Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins

by Sauter, Daniel, Hotter, Dominik, Van Driessche, Benoît, Stürzel, Christina M., Kluge, Silvia F., Wildum, Steffen, Yu, Hangxing, Baumann, Bernd, Wirth, Thomas, Plantier, Jean-Christophe, Leoz, Marie, Hahn, Beatrice H., Van Lint, Carine, Kirchhoff, Frank
Published in Cell reports (Cambridge) (03.02.2015)

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A Phase 2 Randomized Trial Evaluating the Antiviral Activity and Safety of the Direct-Acting Antiviral Bemnifosbuvir in Ambulatory Patients with Mild or Moderate COVID-19 (MOONSONG Study)

A Phase 2 Randomized Trial Evaluating the Antiviral Activity and Safety of the Direct-Acting Antiviral Bemnifosbuvir in Ambulatory Patients with Mild or Moderate COVID-19 (MOONSONG Study)

by Boffito, Marta, Dolan, Eamon, Singh, Karishma, Holmes, William, Wildum, Steffen, Horga, Arantxa, Pietropaolo, Keith, Zhou, Xiao-Jian, Clinch, Barry, Collinson, Neil, Ukachukwu, Vincent
Published in Microbiology spectrum (17.08.2023)

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Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B

Toll-Like Receptor 7 Agonist RG7854 Mediates Therapeutic Efficacy and Seroconversion in Woodchucks With Chronic Hepatitis B

by Wildum, Steffen, Korolowicz, Kyle E, Suresh, Manasa, Steiner, Guido, Dai, Lue, Li, Bin, Yon, Changsuek, De Vera Mudry, Maria Cristina, Regenass-Lechner, Franziska, Huang, Xu, Hong, Xupeng, Murreddu, Marta G, Kallakury, Bhaskar V, Young, John A T, Menne, Stephan
Published in Frontiers in immunology (23.05.2022)

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Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19

Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19

by Bauer, Rebecca N., Teterina, Anastasia, Shivram, Haridha, McBride, Jacqueline, Rosenberger, Carrie M., Cai, Fang, Bao, Min, Tsai, Larry, Gordon, Oliver, Lee, Ivan T., Wallin, Jeffrey J., Porter, Danielle, Juneja, Kavita, Camus, Gregory, Rosas, Ivan O., Wildum, Steffen
Published in Clinical and translational science (01.06.2023)

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Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)

Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)

by Rosas, Ivan O., Bräu, Norbert, Waters, Michael, Go, Ronaldo C., Malhotra, Atul, Hunter, Bradley D., Bhagani, Sanjay, Skiest, Daniel, Savic, Sinisa, Douglas, Ivor S., Garcia-Diaz, Julia, Aziz, Mariam S., Cooper, Nichola, Youngstein, Taryn, Sorbo, Lorenzo Del, Zerda, David J. De La, Ustianowski, Andrew, Gracian, Antonio Cubillo, Blyth, Kevin G., Carratalà, Jordi, François, Bruno, Benfield, Thomas, Haslem, Derrick, Bonfanti, Paolo, van der Leest, Cor H., Rohatgi, Nidhi, Wiese, Lothar, Luyt, Charles Edouard, Bauer, Rebecca N., Cai, Fang, Lee, Ivan T., Matharu, Balpreet, Metcalf, Louis, Wildum, Steffen, Graham, Emily, Tsai, Larry, Bao, Min
Published in EClinicalMedicine (01.05.2022)

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In Vitro and In Vivo Activities of AIC292, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

In Vitro and In Vivo Activities of AIC292, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

by WILDUM, Steffen, PAULSEN, Daniela, THEDE, Kai, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)

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Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model

Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model

by Stannard, Harry L., Mifsud, Edin J., Wildum, Steffen, Brown, Sook Kwan, Koszalka, Paulina, Shishido, Takao, Kojima, Satoshi, Omoto, Shinya, Baba, Keiko, Kuhlbusch, Klaus, Hurt, Aeron C., Barr, Ian G.
Published in Communications biology (28.09.2022)

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Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

by Menne, Stephan, Wildum, Steffen, Steiner, Guido, Suresh, Manasa, Korolowicz, Kyle, Balarezo, Maria, Yon, Changsuek, Murreddu, Marta, Hong, Xupeng, Kallakury, Bhaskar V., Tucker, Robin, Yang, Song, Young, John A.T., Javanbakht, Hassan
Published in Hepatology communications (01.06.2020)

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Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice

Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice

by Priceputu, Elena, Hanna, Zaher, Hu, Chunyan, Simard, Marie-Chantal, Vincent, Patrick, Wildum, Steffen, Schindler, Michael, Kirchhoff, Frank, Jolicoeur, Paul
Published in Journal of Virology (01.05.2007)

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Primary Sooty Mangabey Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2 nef Alleles Modulate Cell Surface Expression of Various Human Receptors and Enhance Viral Infectivity and Replication

Primary Sooty Mangabey Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2 nef Alleles Modulate Cell Surface Expression of Various Human Receptors and Enhance Viral Infectivity and Replication

by MÜNCH, Jan, SCHINDLER, Michael, WILDUM, Steffen, RÜCKER, Elke, BAILER, Nicola, KNOOP, Volker, NOVEMBRE, Francis J, KIRCHHOFF, Frank
Published in Journal of Virology (01.08.2005)

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Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques

Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques

by BRENNER, Matthias, MÜNCH, Jan, TEN HAAFT, Peter, SWIGUT, Tomek, HRECKA, Katarzyna, SKOWRONSKI, Jacek, KIRCHHOFF, Frank, SCHINDLER, Michael, WILDUM, Steffen, STOLTE, Nicole, STAHL-HENNIG, Christiane, FUCHS, Dietmar, MÄTZ-RENSING, Kerstin, FRANZ, Monika, HEENEY, Jonathan
Published in Journal of Virology (01.05.2006)

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Comparison of influenza viral load in nasopharyngeal and midturbinate swabs

Comparison of influenza viral load in nasopharyngeal and midturbinate swabs

by Bernasconi, Corrado, Katugampola, Laurie, Wildum, Steffen
Published in Influenza and other respiratory viruses (01.01.2024)

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In vitro drug combination studies of Letermovir (AIC246, MK-8228) with approved anti-human cytomegalovirus (HCMV) and anti-HIV compounds in inhibition of HCMV and HIV replication

In vitro drug combination studies of Letermovir (AIC246, MK-8228) with approved anti-human cytomegalovirus (HCMV) and anti-HIV compounds in inhibition of HCMV and HIV replication

by Wildum, Steffen, Zimmermann, Holger, Lischka, Peter
Published in Antimicrobial agents and chemotherapy (01.06.2015)

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Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2)

Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2)

by Baker, Jeffrey, Block, Stanley L, Matharu, Balpreet, Burleigh Macutkiewicz, Laura, Wildum, Steffen, Dimonaco, Sophie, Collinson, Neil, Clinch, Barry, Piedra, Pedro A
Published in The Pediatric infectious disease journal (01.08.2020)

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