Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs
Kris, Mark G, Johnson, Bruce E, Berry, Lynne D, Kwiatkowski, David J, Iafrate, A. John, Wistuba, Ignacio I, Varella-Garcia, Marileila, Franklin, Wilbur A, Aronson, Samuel L, Su, Pei-Fang, Shyr, Yu, Camidge, D. Ross, Sequist, Lecia V, Glisson, Bonnie S, Khuri, Fadlo R, Garon, Edward B, Pao, William, Rudin, Charles, Schiller, Joan, Haura, Eric B, Socinski, Mark, Shirai, Keisuke, Chen, Heidi, Giaccone, Giuseppe, Ladanyi, Marc, Kugler, Kelly, Minna, John D, Bunn, Paul A
Published in JAMA : the journal of the American Medical Association (21.05.2014)
Published in JAMA : the journal of the American Medical Association (21.05.2014)
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Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience
Sholl, Lynette M., Aisner, Dara L., Varella-Garcia, Marileila, Berry, Lynne D., Dias-Santagata, Dora, Wistuba, Ignacio I., Chen, Heidi, Fujimoto, Junya, Kugler, Kelly, Franklin, Wilbur A., Iafrate, A. John, Ladanyi, Marc, Kris, Mark G., Johnson, Bruce E., Bunn, Paul A., Minna, John D., Kwiatkowski, David J.
Published in Journal of thoracic oncology (01.05.2015)
Published in Journal of thoracic oncology (01.05.2015)
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Optimizing the Detection of Lung Cancer Patients Harboring Anaplastic Lymphoma Kinase (ALK) Gene Rearrangements Potentially Suitable for ALK Inhibitor Treatment
ROSS CAMIDGE, D, KONO, Scott A, FLACCO, Antonella, TAN, Aik-Choon, DOEBELE, Robert C, QING ZHOU, CRINO, Lucio, FRANKLIN, Wilbur A, VARELLA-GARCIA, Marileila
Published in Clinical cancer research (15.11.2010)
Published in Clinical cancer research (15.11.2010)
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Oncogene status predicts patterns of metastatic spread in treatment‐naive nonsmall cell lung cancer
Doebele, Robert C., Lu, Xian, Sumey, Christopher, Maxson, DeLee A., Weickhardt, Andrew J., Oton, Ana B., Bunn, Paul A., Barón, Anna E., Franklin, Wilbur A., Aisner, Dara L., Varella‐Garcia, Marileila, Camidge, D. Ross
Published in Cancer (15.09.2012)
Published in Cancer (15.09.2012)
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Antigen-Presenting Intratumoral B Cells Affect CD4 + TIL Phenotypes in Non-Small Cell Lung Cancer Patients
Bruno, Tullia C, Ebner, Peggy J, Moore, Brandon L, Squalls, Olivia G, Waugh, Katherine A, Eruslanov, Evgeniy B, Singhal, Sunil, Mitchell, John D, Franklin, Wilbur A, Merrick, Daniel T, McCarter, Martin D, Palmer, Brent E, Kern, Jeffrey A, Slansky, Jill E
Published in Cancer immunology research (01.10.2017)
Published in Cancer immunology research (01.10.2017)
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Molecular Predictors of Outcome With Gefitinib in a Phase III Placebo-Controlled Study in Advanced Non–Small-Cell Lung Cancer
HIRSCH, Fred R, VARELLA-GARCIA, Marileila, VON PAWEL, Joachim, WATKINS, Claire, FLANNERY, Angela, ELLISON, Gillian, DONALD, Emma, KNIGHT, Lucy, PARUMS, Dinah, BOTWOOD, Nicholas, HOLLOWAY, Brian, BUNN, Paul A, FRANKLIN, Wilbur A, DZIADZIUSZKO, Rafal, THATCHER, Nick, CHANG, Alex, PARIKH, Purvish, PEREIRA, José Rodrigues, CIULEANU, Tudor
Published in Journal of clinical oncology (01.11.2006)
Published in Journal of clinical oncology (01.11.2006)
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Increased EGFR Gene Copy Number Detected by Fluorescent In Situ Hybridization Predicts Outcome in Non–Small-Cell Lung Cancer Patients Treated With Cetuximab and Chemotherapy
HIRSCH, Fred R, HERBST, Roy S, OLSEN, Christine, CHANSKY, Kari, CROWLEY, John, KELLY, Karen, FRANKLIN, Wilbur A, BUNN, Paul A, VARELLA-GARCIA, Marileila, GANDARA, David R
Published in Journal of clinical oncology (10.07.2008)
Published in Journal of clinical oncology (10.07.2008)
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KRAS Mutations and Sensitivity to Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer: Practical Application of Patient Selection
JIMENO, Antonio, MESSERSMITH, Wells A, HIRSCH, Fred R, FRANKLIN, Wilbur A, ECKHARDT, S. Gail
Published in Journal of clinical oncology (01.03.2009)
Published in Journal of clinical oncology (01.03.2009)
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Surgery With or Without Preoperative Paclitaxel and Carboplatin in Early-Stage Non–Small-Cell Lung Cancer: Southwest Oncology Group Trial S9900, an Intergroup, Randomized, Phase III Trial
PISTERS, Katherine M. W, VALLIERES, Eric, CROWLEY, John J, FRANKLIN, Wilbur A, BUNN, Paul A, GINSBERG, Robert J, PUTNAM, Joe B, CHANSKY, Kari, GANDARA, David
Published in Journal of clinical oncology (10.04.2010)
Published in Journal of clinical oncology (10.04.2010)
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Epidermal Growth Factor Receptor Gene and Protein and Gefitinib Sensitivity in Non–Small-Cell Lung Cancer
Cappuzzo, Federico, Hirsch, Fred R., Rossi, Elisa, Bartolini, Stefania, Ceresoli, Giovanni L., Bemis, Lynne, Haney, Jerry, Witta, Samir, Danenberg, Kathleen, Domenichini, Irene, Ludovini, Vienna, Magrini, Elisabetta, Gregorc, Vanesa, Doglioni, Claudio, Sidoni, Angelo, Tonato, Maurizio, Franklin, Wilbur A., Crino, Lucio, Bunn, Paul A., Varella-Garcia, Marileila
Published in JNCI : Journal of the National Cancer Institute (04.05.2005)
Published in JNCI : Journal of the National Cancer Institute (04.05.2005)
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Increased Epidermal Growth Factor Receptor Gene Copy Number Detected by Fluorescence In Situ Hybridization Associates With Increased Sensitivity to Gefitinib in Patients With Bronchioloalveolar Carcinoma Subtypes: A Southwest Oncology Group Study
HIRSCH, Fred R, VARELLA-GARCIA, Marileila, MCCOY, Jason, WEST, Howard, XAVIER, Ana Carolina, GUMERLOCK, Paul, BUNN, Paul A, FRANKLIN, Wilbur A, CROWLEY, John, GANDARA, David R
Published in Journal of clinical oncology (01.10.2005)
Published in Journal of clinical oncology (01.10.2005)
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Characteristics of Lung Cancers Harboring NRAS Mutations
OHASHI, Kadoaki, SEQUIST, Lecia V, YUMEI PAN, SASAKI, Hidefumi, ENGELMAN, Jeffrey A, GARON, Edward B, DUBINETT, Steven M, FRANKLIN, Wilbur A, RIELY, Gregory J, SOS, Martin L, KRIS, Mark G, DIAS-SANTAGATA, Dora, ARCILA, Maria E, LADANYI, Marc, BUNN, Paul A, PAO, William, LOVLY, Christine M, XI CHEN, RUDIN, Charles M, MORAN, Teresa, CAMIDGE, David Ross, VNENCAK-JONES, Cindy L, BERRY, Lynne
Published in Clinical cancer research (01.05.2013)
Published in Clinical cancer research (01.05.2013)
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Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis
HIRSCH, Fred R, VARELLA-GARCIA, Marileila, BUNN, Paul A, DI MARIA, Michael V, VEVE, Robert, BREMNES, Roy M, BARON, Anna E, CHAN ZENG, FRANKLIN, Wilbur A
Published in Journal of clinical oncology (15.10.2003)
Published in Journal of clinical oncology (15.10.2003)
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Interobserver Variation among Pathologists and Refinement of Criteria in Distinguishing Separate Primary Tumors from Intrapulmonary Metastases in Lung
Nicholson, Andrew G., Torkko, Kathleen, Viola, Patrizia, Duhig, Edwina, Geisinger, Kim, Borczuk, Alain C., Hiroshima, Kenzo, Tsao, Ming S., Warth, Arne, Lantuejoul, Sylvie, Russell, Prudence A., Thunnissen, Erik, Marchevsky, Alberto, Mino-Kenudson, Mari, Beasley, Mary Beth, Botling, Johan, Dacic, Sanja, Yatabe, Yasushi, Noguchi, Masayuki, Travis, William D., Kerr, Keith, Hirsch, Fred R., Chirieac, Lucian R., Wistuba, Ignacio I., Moreira, Andre, Chung, Jin-Haeng, Chou, Teh Ying, Bubendorf, Lukas, Chen, Gang, Pelosi, Giuseppe, Poleri, Claudia, Detterbeck, Frank C., Franklin, Wilbur A.
Published in Journal of thoracic oncology (01.02.2018)
Published in Journal of thoracic oncology (01.02.2018)
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Defining a Gene Promoter Methylation Signature in Sputum for Lung Cancer Risk Assessment
SHUGUANG LENG, DO, Kieu, HERMAN, James G, BAYLIN, Stephen B, BYERS, Tim, STIDLEY, Christine A, BELINSKY, Steven A, YINGLING, Christin M, PICCHI, Maria A, WOLF, Holly J, KENNEDY, Timothy C, FESER, William J, BARON, Anna E, FRANKLIN, Wilbur A, BROCK, Malcolm V
Published in Clinical cancer research (15.06.2012)
Published in Clinical cancer research (15.06.2012)
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Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort
BELINSKY, Steven A, LIECHTY, Kieu C, FRANKLIN, Wilbur A, HERMAN, James G, BAYLIN, Stephen B, BUNN, Paul A, BYERS, Tim, GENTRY, Frederick D, WOLF, Holly J, ROGERS, Justin, VU, Kieu, HANEY, Jerry, KENNEDY, Tim C, HIRSCH, Fred R, MILLER, York
Published in Cancer research (Chicago, Ill.) (15.03.2006)
Published in Cancer research (Chicago, Ill.) (15.03.2006)
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A Randomized, Phase II, Biomarker-Selected Study Comparing Erlotinib to Erlotinib Intercalated With Chemotherapy in First-Line Therapy for Advanced Non–Small-Cell Lung Cancer
HIRSCH, Fred R, KABBINAVAR, Fairooz, RUSK, Jason, FRANKLIN, Wilbur A, VARELLA-GARCIA, Marileila, BUNN, Paul A, ROSS CAMIDGE, D, EISEN, Tim, MARTINS, Renato, SCHNELL, Fredrick M, DZIADZIUSZKO, Rafal, RICHARDSON, Katherine, RICHARDSON, Frank, WACKER, Bret, STERNBERG, David W
Published in Journal of clinical oncology (10.09.2011)
Published in Journal of clinical oncology (10.09.2011)
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Increased HER2 Gene Copy Number Is Associated With Response to Gefitinib Therapy in Epidermal Growth Factor Receptor–Positive Non–Small-Cell Lung Cancer Patients
CAPPUZZO, Federico, VARELLA-GARCIA, Marileila, FRANKLIN, Wilbur A, CRINO, Lucid, GAZDAR, Adi F, BUNN, Paul A, HIRSCH, Fred R, SHIGEMATSU, Hisayuki, DOMENICHINI, Irene, BARTOLINI, Stefania, CERESOLI, Giovanni L, ROSSI, Elisa, LUDOVINI, Vienna, GREGORC, Vanesa, TOSCHI, Luca
Published in Journal of clinical oncology (01.08.2005)
Published in Journal of clinical oncology (01.08.2005)
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Genetic Abnormalities of the EGFR Pathway in African American Patients With Non–Small-Cell Lung Cancer
LEIDNER, Rom S, PINGFU FU, HIRSCH, Fred R, VARELLA-GARCIA, Marileila, HALMOS, Balazs, CLIFFORD, Bradley, HAMDAN, Ayad, CHENG JIN, EISENBERG, Rosana, BOGGON, Titus J, SKOKAN, Margaret, FRANKLIN, Wilbur A, CAPPUZZO, Federico
Published in Journal of clinical oncology (20.11.2009)
Published in Journal of clinical oncology (20.11.2009)
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Evolving Concepts in the Pathology and Computed Tomography Imaging of Lung Adenocarcinoma and Bronchioloalveolar Carcinoma
Travis, William D, Garg, Kavita, Franklin, Wilbur A, Wistuba, Ignacio I, Sabloff, Bradley, Noguchi, Masayuki, Kakinuma, Ryutaro, Zakowski, Maureen, Ginsberg, Michelle, Padera, Robert, Jacobson, Francine, Johnson, Bruce E, Hirsch, Fred, Brambilla, Elizabeth, Flieder, Douglas B, Geisinger, Kim R, Thunnisen, Frederik, Kerr, Keith, Yankelevitz, David, Franks, Teri J, Galvin, Jeffrey R, Henderson, Douglas W, Nicholson, Andrew G, Hasleton, Philip S, Roggli, Victor, Tsao, Ming-Sound, Cappuzzo, Federico, Vazquez, Madeline
Published in Journal of clinical oncology (10.05.2005)
Published in Journal of clinical oncology (10.05.2005)
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