Due to interleukin-6 type cytokine redundancy only glycoprotein 130 receptor blockade efficiently inhibits myeloma growth
Burger, Renate, Günther, Andreas, Klausz, Katja, Staudinger, Matthias, Peipp, Matthias, Penas, Eva Maria Murga, Rose-John, Stefan, Wijdenes, John, Gramatzki, Martin
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Cytotoxic activity of the maytansinoid immunoconjugate B-B4–DM1 against CD138+ multiple myeloma cells
Tassone, Pierfrancesco, Goldmacher, Victor S., Neri, Paola, Gozzini, Antonella, Shammas, Masood A., Whiteman, Kathleen R., Hylander-Gans, Linda L., Carrasco, Daniel R., Hideshima, Teru, Shringarpure, Reshma, Shi, Jialan, Allam, Charles K., Wijdenes, John, Venuta, Salvatore, Munshi, Nikhil C., Anderson, Kenneth C.
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Syndecan-1 antigen, a promising new target for triple-negative breast cancer immuno-PET and radioimmunotherapy. A preclinical study on MDA-MB-468 xenograft tumors
Rousseau, Caroline, Ruellan, Anne Lise, Bernardeau, Karine, Kraeber-Bodéré, Françoise, Gouard, Sebastien, Loussouarn, Delphine, Saï-Maurel, Catherine, Faivre-Chauvet, Alain, Wijdenes, John, Barbet, Jacques, Gaschet, Joëlle, Chérel, Michel, Davodeau, François
Published in EJNMMI research (01.09.2011)
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A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1
Wijdenes, J, Vooijs, W C, Clément, C, Post, J, Morard, F, Vita, N, Laurent, P, Sun, R X, Klein, B, Dore, J M
Published in British journal of haematology (01.08.1996)
Published in British journal of haematology (01.08.1996)
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Expression of Interleukin 13 Receptor in Glioma and Renal Cell Carcinoma: IL13Rα2 as a Decoy Receptor for IL13
Bernard, Jérôme, Treton, Dominique, Vermot-Desroches, Claudine, Boden, Christine, Horellou, Philippe, Angevin, Eric, Galanaud, Pierre, Wijdenes, John, Richard, Yolande
Published in Laboratory investigation (01.09.2001)
Published in Laboratory investigation (01.09.2001)
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Soluble IL-6 Receptor Potentiates the Antagonistic Activity of Soluble gp130 on IL-6 Responses
Muller-Newen, Gerhard, Kuster, Andrea, Hemmann, Ulrike, Keul, Radovan, Horsten, Ursula, Martens, Astrid, Graeve, Lutz, Wijdenes, John, Heinrich, Peter C
Published in The Journal of immunology (1950) (01.12.1998)
Published in The Journal of immunology (1950) (01.12.1998)
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Alleviation of Systemic Manifestations of Castleman's Disease by Monoclonal Anti-Interleukin-6 Antibody
Beck, Joseph T, Hsu, Su-Ming, Wijdenes, John, Bataille, Regis, Klein, Bernard, Vesole, David, Hayden, Katherine, Jagannath, Sundar, Barlogie, Bart
Published in The New England journal of medicine (03.03.1994)
Published in The New England journal of medicine (03.03.1994)
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The myeloma cell antigen syndecan‐1 is lost by apoptotic myeloma cells
Jourdan, Michel, Ferlin, Martine, Legouffe, Eric, Horvathova, Mira, Liautard, Janny, Rossi, Jean FranÇois, Wijdenes, John, Brochier, Jean, Klein, Bernard
Published in British journal of haematology (01.03.1998)
Published in British journal of haematology (01.03.1998)
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Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells
VAN DEN BERG, J. G, ATEN, J, CHAND, M. A, CLAESSEN, N, DIJKINK, L, WIJDENES, J, LAKKIS, F. G, WEENING, J. J
Published in Journal of the American Society of Nephrology (01.03.2000)
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Characterization of monoclonal antibodies directed against trail or trail receptors
Vermot-Desroches, Claudine, Sergent, Elise, Bonnin, Brigitte, Wijdenes, John
Published in Cellular Immunology (01.07.2005)
Published in Cellular Immunology (01.07.2005)
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Studies on the Interleukin-6-type Cytokine Signal Transducer gp130 Reveal a Novel Mechanism of Receptor Activation by Monoclonal Antibodies
Müller-Newen, Gerhard, Küster, Andrea, Wijdenes, John, Schaper, Fred, Heinrich, Peter C.
Published in The Journal of biological chemistry (18.02.2000)
Published in The Journal of biological chemistry (18.02.2000)
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The Immunoglobulin-like Module of gp130 Is Required for Signaling by Interleukin-6, but Not by Leukemia Inhibitory Factor
Hammacher, Annet, Richardson, Rachael T., Layton, Judith E., Smith, David K., Angus, Leecia J.L., Hilton, Douglas J., Nicola, Nicos A., Wijdenes, John, Simpson, Richard J.
Published in The Journal of biological chemistry (28.08.1998)
Published in The Journal of biological chemistry (28.08.1998)
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High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo
Lu, Z Y, Brochier, J, Wijdenes, J, Brailly, H, Bataille, R, Klein, B
Published in European journal of immunology (01.11.1992)
Published in European journal of immunology (01.11.1992)
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Cyclosporin A inhibition of macrophage colony-stimulating factor (M-CSF) production by activated human T lymphocytes
Frétier, Stéphanie, Besse, Arnaud, Delwail, Adriana, Garcia, Martine, Morel, Franck, Leprivey‐Lorgeot, Valérie, Wijdenes, John, Praloran, Vincent, Lecron, Jean‐Claude
Published in Journal of leukocyte biology (01.02.2002)
Published in Journal of leukocyte biology (01.02.2002)
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Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function
Kubach, Jan, Lutter, Petra, Bopp, Tobias, Stoll, Sabine, Becker, Christian, Huter, Eva, Richter, Christoph, Weingarten, Petra, Warger, Tobias, Knop, Jürgen, Müllner, Stefan, Wijdenes, John, Schild, Hansjörg, Schmitt, Edgar, Jonuleit, Helmut
Published in Blood (01.09.2007)
Published in Blood (01.09.2007)
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IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner
Loyon, Romain, Picard, Emilie, Mauvais, Olivier, Queiroz, Lise, Mougey, Virginie, Pallandre, Jean-René, Galaine, Jeanne, Mercier-Letondal, Patricia, Kellerman, Guillaume, Chaput, Nathalie, Wijdenes, John, Adotévi, Olivier, Ferrand, Christophe, Romero, Pedro, Godet, Yann, Borg, Christophe
Published in The Journal of immunology (1950) (01.07.2016)
Published in The Journal of immunology (1950) (01.07.2016)
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Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M
Gu, Zong-Jiang, Wijdenes, John, Zhang, Xue-Guang, Hallet, Marie-Martine, Clement, Claude, Klein, Bernard
Published in Journal of immunological methods (28.03.1996)
Published in Journal of immunological methods (28.03.1996)
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Clinical and biologic effects of anti–interleukin‐10 monoclonal antibody administration in systemic lupus erythematosus
Llorente, Luis, Richaud‐Patin, Yvonne, García‐Padilla, Carlos, Claret, Emmanuel, Jakez‐Ocampo, Juan, Cardiel, Mario H., Alcocer‐Varela, Jorge, Grangeot‐Keros, Liliane, Alarcón‐Segovia, Donato, Wijdenes, John, Galanaud, Pierre, Emilie, Dominique
Published in Arthritis and rheumatism (01.08.2000)
Published in Arthritis and rheumatism (01.08.2000)
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